A5049741834- Liver Disease Diagnosis and Treatment
- Connective Tissue Growth Factor Research
- Pancreatitis Pathology and Treatment
- Gut microbiota and health
- Inflammatory Bowel Disease
- GDF15 and Related Biomarkers
- Protease and Inhibitor Mechanisms
- Pancreatic and Hepatic Oncology Research
Medical University of Białystok
2015-2021
Metabolic profiling might be used to identify disease biomarkers. The aim of our study was determine the usefulness untargeted metabolomics analysis detect differences in serum metabolites between newly diagnosed and untreated pediatric patients with Crohn's (CD) or ulcerative colitis (UC) comparison a control group (Ctr). Moreover, we investigated potential inflammatory markers improve noninvasive diagnosis CD UC children. fingerprinting samples estimated liquid chromatography coupled mass...
Mild cognitive impairment (MCI) is often found to be a transitional stage between normal aging and dementia, especially Alzheimer's disease (AD). The associations AD matrix metalloproteinase-9 (MMP-9) were discussed in the literature obtained results are not consistent. However, little known about relationships MCI metalloproteinases. aim of our study was determination MMP-9 cerebrospinal fluid (CSF) patients with mild comparison these levels commonly used biomarker, amyloid beta 1-42...
Epidemiological studies have demonstrated a strong association between cigarette smoking (CS) and chronic pancreatitis (CP); however, the exact mechanisms of this phenomenon remains unknown. The authors previously shown that increased Ras expression activates NF-κB mediated pathway promotes development CP. However, it is unclear whether similar occurs in CS-induced Therefore, aim study was to determine CS increases K-Ras, CP mice exposed repeated episodes acute (AP).C57BL6/cmdb were or sham...