Silver screen: The AgNO3-catalyzed carbon phosphorylation of alkenes occurs by an alkene addition/cyclization cascade. Ag+ reacts with Ph2P(O)H to form the crucial active intermediate 1, which promotes reaction. This method requires a cheap, nontoxic silver salt as catalyst and substrates for transformation are simple readily accessible.

A novel and inexpensive method of nontoxic, silver-salt-catalyzed carboazidation arylacrylamides to afford corresponding azide oxindoles is reported. This reaction system exhibits great functional group tolerance. All products form a crucial skeleton for the synthesis various indole alkaloids.

A novel metal-free oxidative carbonitration of alkenes by a nitration and C–H functionalization cascade process has been developed. This methodology provides an efficient way to construct valuable nitro-containing oxindoles.

Silberstreif: Die AgNO3-katalysierte Kohlenstoffphosphorylierung von Alkenen verläuft über eine Additions-Cyclisierungs-Kaskade. Ag+ reagiert mit Ph2P(O)H zur aktiven Zwischenstufe 1, die Reaktion katalysiert. Methode benötigt lediglich ein preiswertes ungiftiges Silbersalz als Katalysator und ist auf einfache, leicht zugängliche Substrate anwendbar.

Oxidative radical addition/cyclization cascade of o-cyanoarylacrylamides with α-keto acids as well aldehydes is reported. This transformation exhibits a wide substrate scope and significant functional group tolerance provides convenient highly efficient access to carbonyl-containing quinoline-2,4(1H,3H)-diones. A possible mechanism for the proposed.

This study comprehensively investigated the catalytic performance of lanthanide rare earth metals (REMs) anchored into Salen for CO 2 RR in terms stability, selectivity, and activity using density functional theory (DFT).

Abstract A copper‐mediated oxidative radical addition/cyclization cascade of o ‐cyanoarylacrylamides with sodium trifluoromethanesulfonate (Langlois’ reagent) has been achieved. The reaction proceeds through addition, cyclization, and imine hydrolysis, in which the cyclization was accomplished by an intramolecular addition carbon to nitrile. This transformation exhibits a wide substrate scope good functional group tolerance, thus providing highly efficient practical access variety...

A copper-catalyzed decarboxylative disulfonylation of alkynyl carboxylic acids with sulfinic in aqueous solution has been developed. The reaction provides a straightforward and practical access to (E)-1,2-disulfonylethenes, which are important building blocks synthetic organic chemistry, exhibits good functional group tolerance excellent stereoselectivity. possible mechanism for the transformation is proposed.

The separation of ethylene glycol (EG) and 1,2-butanediol (1,2-BDO) azeotrope in the synthesis process EG via coal biomass is becoming increasingly commercial environmental importance. Selective adsorption deemed as most promising method because energy savings environment favorability. In this study, we developed an interpretable decision tree (DT) model to facilitate high-throughput screening covalent organic frameworks (COFs) adsorbents for EG/1,2-BDO mixtures, achieving R2 value 0.96....

Azomethine imines as a class of important dipoles have been widely employed in enantioselective 1,3-dipolar cycloaddition reactions. Copper-catalyzed azomethine with alkynes is one the most...

A novel and facile Cu-catalyzed addition/cyclization cascade of o-cyanoarylacrylamide was developed. The process exhibits significant functional group tolerance, provides an efficient straightforward pathway for the synthesis various phosphonylated quinoline-2,4(1H,3H)-diones.

A novel radical [2 + 2 1] cyclization of ortho-cyanoarylacrylamides with dual α-C–H bonds in alkyl nitriles has been developed. The reaction provides new facile and straightforward access to cyano-substituted pyrrolo[3,2-c]quinolines, which are important nitrogen-containing polyheterocycles. possible mechanism for the transformation is proposed.

Abstract A facile, metal‐free protocol has been developed for the remote trifluoromethylation of 8‐aminoquinoline scaffolds on C5 position, which is difficult to functionalize. In this method, 8‐aminoquinolineamides reacted with an inexpensive and commercially available CF 3 source (Langlois reagent) give a wide range trifluoromethylated aminoquinolineamides.

A novel copper-catalyzed decarboxylative oxyalkylation of alkynyl carboxylic acids with ketones and alkylnitriles via direct C(sp3)-H bond functionalization to construct new C-C bonds C-O double was developed. This transformation is featured by wide functional group compatibility the use readily available reagents, thus affording a general approach γ-diketones γ-ketonitriles. possible mechanism proposed.

A photoredox decarboxylative coupling of N-hydroxyphthalimide esters with aldimines is reported for synthesizing α-amino esters. broad scope alkyl radicals generated under visible light irradiation adds to glyoxylate in reliably good excellent yields. Adding inorganic bases such as potassium carbonate significantly enhanced the yields by suppressing umpolung side reaction. The computation study suggests that base facilitates hydrogen atom transfer from radical cation Hantzsch ester...

A direct method for the synthesis of 1,3,4-triarylpyrroles was achieved easily from cyclization α-amino carbonyl compounds and aldehydes catalyzed by I2. Various substituted groups can be employed, this reaction proceed smoothly in moderate to good yields.

A conversion of pyridines and enamides for the synthesis 3-bromo-imidazo[1,2-a]pyridines was developed by copper-mediated aerobic oxidative coupling in a one-pot manner. This procedure tolerates various functional groups affords series under mild conditions.

Quinolines and succinimides play a crucial role in many pharmaceutical natural products. Although sp2 C–H bond addition reactions have been extensively investigated, Co(III)-catalyzed sp3 1,4-addition are relatively unexplored. In this manuscript, an efficient atom-economic protocol for alkylation of 8-methylquinolines with maleimides is presented. The reaction exhibits exceptional reactivity, satisfactory yields, excellent chemo- regioselectivity, tolerates variety functional groups.

Oxidative radical cascade cyclizations of 2-cyano-3-arylaniline derived acrylamides with acetonitrile and <italic>tert</italic>-butyl peroxybenzoate have been developed to construct cyano methyl substituted pyrido[4,3,2-<italic>gh</italic>]phenanthridines.

Free radical carbochloromethylations of ortho-cyanoarylacrylamides and N-(arylsulfonyl)acrylamides have been developed by employing simple alkyl chlorides as the chloromethyl source. The transformations are characterized wide functional group compatibility utilizing readily available reagents, thus providing efficient methods for constructing polychloromethyl-substituted quinoline-2,4-diones α-aryl-β-polychloromethylated amides.