A copper-catalyzed method for the synthesis of imidazo[1,2-a]pyridines with aminopyridines and nitroolefins using air as oxidation agent in a one-pot procedure has been developed. In this process, reaction appears to be very general suitable construction variety imidazo[1,2-a]pyridines.

A straightforward method for the synthesis of polysubstituted pyrroles was achieved easily from oxidative cyclization beta-enamino ketones or esters and alkynoates catalyzed by CuI in presence O(2).

A direct method has been developed for iodine-mediated thiolation of naphthols/naphthylamines and arylsulfonyl hydrazides through the formation C-S bond cleavage S-N/S-O bonds. In this transformation, a range valuable thioethers are easily achieved in moderate to good yields.

An efficient method for the direct synthesis of substituted quinolines from anilines and aldehydes through C-H functionalization, C-C/C-N bond formation, C-C cleavage has been developed. The is simple practical employs air as an oxidant.

We report the conjugated polymer P(tBu-CBP) as a host with high triplet energy (ET 2.53 eV) and suitable HOMO (5.3 LUMO (2.04 levels. Upon doping green red emission Ir-complexes, it gives devices luminous external quantum efficiencies for (23.7 cd/A, 6.57%) (5.1 4.23%), respectively, low turn-on voltage (3 V). For both devices, are higher than those of corresponding same backbone P(3,6-Cz) by factor 4, even though latter has an ET (2.6 slightly that former. The results reflect that, in...

An efficient method for the Pd-catalyzed regioselective C-2 arylation of quinolines is presented. Reactions various substituted and unactivated arenes have been conducted under mild conditions. The result shows good product yields 2-arylquinolines, which are highly useful building blocks synthesis bioactive alkaloid natural products drug molecules.

A direct method for the synthesis of substituted indolizines by means I2-mediated oxidative tandem cyclization via C-N/C-C bond formation was developed. Various aromatic/aliphatic enolizable aldehydes and 2-pyridylacetates/acetonitrile/acetone proceeded smoothly in this transformation, desired products were generated moderate to good yields.

A variety of ways to synthesize imidazo[1,2-<i>a</i>]pyridines have been reported and many approaches are devoted the functionalization imidazo[1,2-<i>a</i>]pyridines. However, use a denitration reaction in synthesis has not reported. We report here iron-catalyzed 3-methyl-2-arylimidazo [1,2-<i>a</i>] pyridine derivatives from aminopyridines 2-methyl-nitroolefins. The procedure, using FeCl₂ as catalyst, is simple inexpensive. Various functional groups tolerated provide products...

Abstract An iron(III)‐catalyzed one‐pot three‐component cross‐coupling nitration reaction of 2‐aminopyridines, aldehydes and nitroalkanes, straightforwardly forms imidazo[1,2‐ a ]pyridine derivatives is described in this report. The system shows good functional‐group tolerance proceeds smoothly moderate to yields.

An I2-promoted, metal-free domino protocol for one-pot synthesis of 1,3,4-oxadiazoles has been developed via oxidative cleavage C(sp2)–H or C(sp)–H bonds, followed by cyclization and deacylation. In this reaction, the use K2CO3 as a base is found to be an essential factor in C–C bond cleavage. This procedure proceeded smoothly moderate high yields with good functional group compatibility.

Abstract A novel and efficient protocol for the C‐2 selective olefination of pyridines via a palladium‐catalyzed oxidative cross‐coupling reaction has been developed. wide range olefin substrates including acrylic ester, styrene, acrylamide are compatible. The products highly useful building blocks synthesis bioactive alkaloid natural drug molecules.

Indole is a ubiquitous structural motif with important applications in many areas of chemistry. Given this, simple and efficient Ru(ii)-catalyzed synthesis indole via intermolecular annulation N-aryl-2-aminopyridines sulfoxonium ylides was proposed accomplished. Excellent selectivity good functional group tolerance this transformation were observed. This protocol provides easy access to wide variety useful indoles the presence commercially available [Ru(p-cymene)Cl2]2 catalyst. A possible...

A concise and efficient protocol for PhI(OAc)₂ oxidation halogenation of quinoline at the C5 position was developed, affording desired remote C–H activation products in moderate to excellent yields.

Abstract A new iron(III)‐catalyzed synthesis of β‐oxo sulfones is described that employs vinylarenes and readily available dimethyl sulfoxide (DMSO) with hydrazine oxygen as the oxidant. The reaction tolerates various functional group substituents on vinylarene substrates to afford in moderate good yields. cleavage formation C–S bond are key steps this transformation.

Abstract A facile, metal‐free protocol has been developed for the remote trifluoromethylation of 8‐aminoquinoline scaffolds on C5 position, which is difficult to functionalize. In this method, 8‐aminoquinolineamides reacted with an inexpensive and commercially available CF 3 source (Langlois reagent) give a wide range trifluoromethylated aminoquinolineamides.

A direct method for the synthesis of 1,3,4-triarylpyrroles was achieved easily from cyclization α-amino carbonyl compounds and aldehydes catalyzed by I2. Various substituted groups can be employed, this reaction proceed smoothly in moderate to good yields.

A novel one-pot three-component synthesis of 3-nitro-2-arylimidazo[1,2-a]pyridines has been easily achieved with 2-aminopyridines, aromatic aldehydes, and MeNO2, is catalyzed by CuBr under air. The procedure, using air as an oxidative agent, simple, low cost, sustainable. Various functional groups are tolerated in this reaction system, it proceeds well moderate to good yields. Detailed facts importance specialist readers published "Supporting Information". Such documents peer-reviewed, but...

A novel iodine-mediated oxidative tandem cyclization reaction of simple enaminones has been developed for the synthesis substituted furopyridines through C-C/C-N/C-O bond formation in a one-pot procedure. Substituted are obtained moderate to good yield. In addition, I- and Br-substituted have successfully produced by electrophilic substitution N-iodo- or N-bromosuccinimide.

A conversion of pyridines and enamides for the synthesis 3-bromo-imidazo[1,2-a]pyridines was developed by copper-mediated aerobic oxidative coupling in a one-pot manner. This procedure tolerates various functional groups affords series under mild conditions.

Abstract A novel and selective method for the simple copper‐catalyzed α‐amination of α‐aminocarbonyl compounds to afford 2‐amino‐2‐iminocarbonyl 2‐amino‐2‐oxocarbonyl is reported. This transformation achieved by C( sp 3 )−H N−H bond oxidative cross‐coupling C−N cleavage. reaction system has a broad scope, providing facile pathway α‐functionalization α‐amino ketones. magnified image