A5100858331- Cancer-related molecular mechanisms research
- Wheat and Barley Genetics and Pathology
- Plant Disease Resistance and Genetics
- Genetic Mapping and Diversity in Plants and Animals
- Circular RNAs in diseases
- Air Quality Monitoring and Forecasting
- Natural Language Processing Techniques
- Neurogenesis and neuroplasticity mechanisms
- Environmental Toxicology and Ecotoxicology
- Aquatic Ecosystems and Phytoplankton Dynamics
- Antimicrobial Peptides and Activities
- Marine Biology and Environmental Chemistry
- Heavy metals in environment
- Ecology and Conservation Studies
- Topic Modeling
- Water Quality and Pollution Assessment
- Asthma and respiratory diseases
- Plant-Microbe Interactions and Immunity
- Radioactivity and Radon Measurements
- Atmospheric chemistry and aerosols
- Physiological and biochemical adaptations
- demographic modeling and climate adaptation
- Postharvest Quality and Shelf Life Management
- Lipid metabolism and biosynthesis
- Atmospheric aerosols and clouds
Sun Yat-sen University
2025
Hebei Academy of Agriculture and Forestry Sciences
2013-2024
Hebei Science and Technology Department
2024
Shandong University of Traditional Chinese Medicine
2022-2024
Tongji University
2020
Tongji Hospital
2020
University of Ottawa
1999-2017
Sichuan University
2016
West China Hospital of Sichuan University
2016
Zhejiang Environmental Monitoring Center
2016
Recent research, such as BitNet, is paving the way for a new era of 1-bit Large Language Models (LLMs). In this work, we introduce LLM variant, namely BitNet b1.58, in which every single parameter (or weight) ternary {-1, 0, 1}. It matches full-precision (i.e., FP16 or BF16) Transformer with same model size and training tokens terms both perplexity end-task performance, while being significantly more cost-effective latency, memory, throughput, energy consumption. More profoundly, 1.58-bit...
Foxtail millet (Setaria italica) is a drought-resistant, barren-tolerant grain crop and forage. Currently, it has become new model plant for cereal crops biofuel grasses. Although two reference genome sequences were released recently, comparative genomics research on foxtail still in its infancy. Using the Solexa sequencing technology, we performed re-sequencing one important Landrace, Shi-Li-Xiang (SLX). Compared with sequences, following genetic variation patterns identified: 762,082 SNPs,...
Inhibitors of HIV protease have been shown to antiapoptotic effects in vitro, yet whether these are seen vivo remains controversial. In this study, we evaluated the impact inhibitor (PI) nelfinavir, boosted with ritonavir, models nonviral disease associated excessive apoptosis. mice Fas-induced fatal hepatitis, Staphylococcal enterotoxin B-induced shock, and middle cerebral artery occlusion-induced stroke, demonstrate that PIs significantly reduce apoptosis improve histology, function,...
Braak and Del Tredici have proposed that typical Parkinson disease (PD) has its origins in the olfactory bulb gastrointestinal tract. However, role of system insufficiently been explored pathogeneses PD Alzheimer (AD) laboratory models. Here, we demonstrate applications a new method to process mouse heads for microscopy by sectioning, mounting, staining whole skulls ('holocranohistochemistry'). This technique permits visualization from nasal cavity mitral cells dopamine-producing...
Abstract Background The use of electronic cigarettes (ECIGs) is increasing, but the impact ECIG-vapor on cellular processes like inflammation or host defense are less understood. aim present study was to compare acute effects traditional (TCIGs) and ECIG-exposure defense, inflammation, activation cell lines primary differentiated human airway epithelial cells (pHBE). Methods We exposed pHBEs several TCIG-smoke ECIG-vapor. Epithelial barrier integrity were determined. transcriptome compared...
Infertility is a global reproductive-health problem, and diminished ovarian reserve (DOR) one of the common causes female infertility. Long noncoding RNAs (lncRNAs) are crucial regulators numerous physiological pathological processes in humans. However, whether lncRNAs involved development DOR remains to be elucidated.Ovarian granulosa cells (OGCs) extracted from infertile women with normal (NOR) were subjected high-throughput sequencing. Comprehensive bioinformatics analysis was conducted...
Foxtail millet (Setaria italica) is an important food and fodder grain crop that grown for human consumption. Production of this species affected by several plant diseases, such as rust. The cultivar Shilixiang has been identified resistant to the foxtail rust pathogen, Uromyces setariae-italicae. In order identify signaling pathways genes related plant's defense mechanisms against rust, was used construct a digital gene expression (DGE) library during interaction with U. study, we...
Background: Heavy drinking can increase heart rate and blood glucose, induce hypoxic tolerance, impair brain cognitive functions, alter gene expressions. These phenomena may occur even in response to small dose of ethanol exposure or during its withdrawal. Objectives: To evaluate whether persistent low concentrations affect organism function the expressions ion channels. Methods: Daphnids were randomized receive placebo 300 min, 2 mM 240 min then 60 min. Heart rate, glucose levels,...
<title>Abstract</title> Long non-coding RNAs (lncRNAs) play an important role in ovarian aging by affecting the biological functions of granulosa cells (GCs) through multiple mechanisms. The lncRNA NEAT1 is significantly downregulated ovaries; however, exact regulatory mechanism has not been elucidated. In current study, we aimed to investigate effects GC during and explore its therapeutic potential. We observed that expression GCs older patients with diminished reserve (DOR), which closely...
Sequential extraction was used to characteristic the heavy metals (Cd, Cr, Zn, Cu, Ni and Pb) trace element (As) studied in these urban dusts. The ratio of average total content (F1+F2+F3+F4+R) corresponding background value Beijing soil decreased order Cd>Pb>Cu>Zn>Ni>Cr>As. For fraction distribution, residual form predominated among for Ni, Cr Pb. Oxidizable leading Cd Cu second dominated Zn Ni. results Risk assessment code (RAC) showed medium environmental risk found...