In this study, the 10-year cardiovascular risk associated with comorbid sleep disorders (insomnia disorder, obstructive apnea syndrome, and COMISA [comorbid insomnia apnea]) was investigated for patients major depression. To enable our analysis, 607 depression were selected from data register of Sleep Unit. High considered present when Framingham Risk Score ≥10%. The has been assessed using logistic regression analyzes. is significant (40.4%) in After successive introduction different...

Several studies have investigated the prevalence and risk factors of insomnia in subjects with obstructive sleep apnea syndrome. However, few for syndrome sufferers. Thus, aim this study was to examine moderate severe a large sample Data from 1311 sufferers who were recruited research database laboratory Erasme Hospital analysed. An apnea-hypopnea index ≥15 events per hour used as cut-off score Logistic regression analyses conducted clinical demographic The our 13.88%. Multivariate logistic...

Given the limited data available, aim of this study was to examine 10-year cardiovascular disease (CVD) risk associated with comorbid insomnia disorder and its specific subtypes in apnoeic individuals. Data from 1104 individuals recruited database Erasme Hospital Sleep Laboratory were analysed. Only a Framingham Risk Score ≥10% included group at moderate-to-high CVD risk. Logistic regression analyses conducted Moderate-to-high present 59.6% our sample. After adjustment for main confounding...

Due to the few studies available, this study aimed investigate 10-year risk for cardiovascular disease (CVD) associated with COMISA (co-morbid insomnia and sleep apnea) in hypertensive subjects. Clinical data of 1009 subjects extracted from Sleep Laboratory database were analyzed. Framingham Risk Score ≥ 10% was used as a cut-off identify high CVD. The association between CVD investigated using logistic regression analyses. 65.3% our sample presented After controlling major confounding...

Our aim is to verify empirically the existence of a major depressed subgroup with similar polysomnographic pattern as primary insomnia, including at rapid eye movement sleep level. The data from 209 untreated individuals (30 normative, 84 insomnia sufferers, and 95 patients objective insomnia) who were recruited retrospectively Erasme hospital database studied for whole night thirds night. Primary sufferers exhibit both (excess wake after onset, deficit in slow-wave sleep/rapid sleep,...

Given the conflicting data available in literature, this study aimed to investigate impact of obstructive sleep apnea syndrome (OSAS) on macular vascular density (VD) and perfusion (PD).

Several studies have investigated the prevalence and risk factors of depression in subjects with obstructive sleep apnea syndrome. However, few for syndrome major depression. The aim this study was to examine moderate severe a large sample individuals Data from 703 recruited research database laboratory Erasme Hospital were analysed. An apnea-hypopnea index ≥15 events per hour used as cut-off score Logistic regression analyses conducted clinical demographic is 13.94%. Multivariate logistic...

The aim of the present study was to investigate risk nonremission following electroconvulsive therapy (ECT), as associated with borderline personality disorder, in individuals major depression context contradictory data available literature.We analyzed demographic and clinical from 210 who were treated ECT. Study participants recruited medical records database Psychiatry Department at Erasme Hospital. Only remission, demonstrated during systematic psychiatric interview performed end ECT (ie,...

Abstract Aims Glioblastoma (GBM) is the most common and lethal malignant brain tumor in adults. Glioma stem cells (GSCs) are implicated this poor prognosis radio(chemo‐)resistance. We have previously demonstrated that among potentially highly specific GSC markers oligodendrocyte lineage transcription factor 2 (OLIG2) appears to be cyclin D2 (CCND2) only one related cell cycle regulation. The purpose of work was investigate clinical significance evolution OLIG2 CCND2 protein expression GBM....

In the general population, co-morbid insomnia and sleep apnoea (COMISA) is associated with higher risk of cardiovascular diseases (CVD). However, despite a high prevalence COMISA in type 2 diabetics, no study has investigated its potential implication negative outcome this particular subpopulation. The aim was therefore to examine CVD diabetics.Data from 471 diabetics recruited clinical database Erasme Hospital laboratory were analysed. Only SCORE index ≥5% included group at CVD. Logistic...

There is evidence for a particular relationship between low-grade inflammation (LGI) and intermittent hypoxia (IH) related to obstructive sleep apnoea syndrome (OSAS). However, despite the potential deleterious cardiovascular consequences associated with this LGI in hypertensive patients, few studies have investigated impact of IH OSAS on CRP levels subpopulation. In total, 1404 patients were selected retrospectively from Sleep Laboratory database. ≥3 mg/L but <10 used as cut-offs...

Given the limited data in literature, aim of this study was to investigate association between type 2 diabetes and anhedonic subtype major depression hypertensive individuals. Demographic polysomnographic from 323 individuals recruited database Erasme Hospital Sleep Laboratory were analysed. Only with a diagnosis according diagnostic criteria American Diabetes Association at admission included "diabetes group". Logistic regression analyses used The rate 18.9% our sample After adjusting for...