- Child and Adolescent Health
- Tracheal and airway disorders
- Human Health and Disease
- Neonatal Respiratory Health Research
- Diabetes and associated disorders
- Foreign Body Medical Cases
- Clinical practice guidelines implementation
- COVID-19 Clinical Research Studies
- Neonatal Health and Biochemistry
- Sepsis Diagnosis and Treatment
- Musicology and Musical Analysis
- Infant Development and Preterm Care
- Historical Influence and Diplomacy
- Impact of Technology on Adolescents
- Bach Studies and Logistics Development
- Complement system in diseases
- Health Sciences Research and Education
- COVID-19 Impact on Reproduction
- Esophageal and GI Pathology
- Diabetes Management and Research
- Neonatal and Maternal Infections
- Otolaryngology and Infectious Diseases
- Diet and metabolism studies
- Lysosomal Storage Disorders Research
- Child Nutrition and Feeding Issues
University of Split
2005-2025
Klinički Bolnički Centar Split
2013-2023
University of Alabama at Birmingham
2022
Society of Critical Care Medicine
2022
Queen's University Belfast
2011-2014
Czech Academy of Sciences, Institute of Ethnology
2014
Abstract ARGONAUTE-2 and associated miRNAs form the RNA-induced silencing complex (RISC), which targets mRNAs for translational degradation as part of RNA interference pathway. Despite essential nature this process cellular function, there is little information on role RISC components in human development organ function. We identify 13 heterozygous mutations AGO2 21 patients affected by disturbances neurological development. Each identified single amino acid result impaired shRNA-mediated...
Objectives: Multicenter data on the characteristics and outcomes of children hospitalized with coronavirus disease 2019 are limited. Our objective was to describe characteristics, ICU admissions, among using Society Critical Care Medicine Discovery Viral Infection Respiratory Illness Universal Study: Coronavirus Disease registry. Design: Retrospective study. Setting: Study (Coronavirus 2019) Patients: Children (< 18 yr) at participating hospitals from February 2020 January 2021....
Background and objectives: Outcomes of neonates diagnosed with esophageal atresia (EA), a rare congenital malformation, vary widely. Due to limited fragmented data globally, major regional centers offer crucial opportunity better understand EA's epidemiology the management. This study aimed address these gaps by determining total birth prevalence early treatment outcomes EA in southern Croatia. Methods: All cases (1991-2020) were retrospectively ascertained from medical documentation at only...
For the countries of southeast Europe, joining European Union would mean a fundamental reassessment beliefs, attitudes, values, and structures developed during 50 years communist regimes.1 This include their healthcare systems training professionals. Medical schools in Europe will need to restructure medical curriculums within unified Europe.2 students have learn modern evidence based medicine,3 for which they not been prepared, mainly because weak research output inadequate education...
Aim To determine the effect of late preterm birth and treatment at intensive care unit (ICU) on school-age children's emotional behavioral problems quality life (QoL).Emotional QoL were investigated in 6-12-year-olds who born University Hospital Center Split period from January 2002 to March 2008. The study included 126 children treated ICU (LP-ICU group), 127 not (LP-non-ICU 131 full-term (FT-ICU group). Emotional difficulties assessed using Child Behavior Checklist. was evaluated with...
Implementation of checklists has been shown to be effective in improving patient safety. This study aims evaluate the effectiveness implementation a checklist for daily care processes into clinical practice pediatric intensive units (PICUs) with limited resources.
Abstract Background Hospitalized patients with SARS-CoV2 develop acute kidney injury (AKI) frequently, yet gaps remain in understanding why adults seem to have higher rates compared children. Our objectives were evaluate the epidemiology of SARS-CoV2-related AKI across age spectrum and determine if known risk factors such as illness severity contribute its pattern. Methods Secondary analysis ongoing prospective international cohort registry. was defined by KDIGO-creatinine only criteria....
Background and objective: There is an increasing risk of type 1 diabetes mellitus (T1D) among children in Croatia. Diabetic ketoacidosis (DKA) the leading cause morbidity mortality with T1D, cerebral edema as most severe complication. Since early recognition leads to a better outcome, it important that patients moderate or DKA are closely monitored treated pediatric intensive care units (PICUs). The aim this study investigate clinical laboratory parameters, well complications PICUs because...
Abstract Background One of the frequently used methods for assessing research trends and impact published scientific literature in a particular discipline is citation analysis. Journals may strive to improve their metrics by choosing manuscripts study designs that are more likely be cited. The aim this was identify 50 most-cited articles field pediatrics, analyze design other characteristics those articles, assess prevalence systematic reviews among them. Methods In December 2017, we...
The aim of this study was to compare the level stress in mothers school-aged children born late preterm and admitted intensive care unit (ICU) with maternal if a child not ICU as well full-term ICU.In retrospective cohort data were gathered via telephone interview mothers. Parenting Stress Index/Short Form used determine Background demographic characteristics, medically relevant variables, tested using chi-square test Kruskal-Wallis test. Logistic regression order identify predictors...
Abstract Rationale: Two clinical cases are reported of envenomation by the nose-horned viper ( Vipera ammodytes ) venom a 9-year-old boy and an 84-year-old woman. Patient concerns: Both patients had been bitten on their extremities such snake in August near Split, town southern Croatia. Diagnoses: Clinical manifestation was severe case boy, being characterized coagulopathy. This only just apparent elderly woman, who suffered extensive local edema hematoma at site bite, together with...
There is limited evidence for therapeutic options pediatric COVID-19 outside of multisystem inflammatory syndrome in children (MIS-C).
Background and Objectives: When the human body is disabled to naturally ingest food through mouth, enteral or parenteral nutritional support should be started. Percutaneous gastrostomy (PEG) a flexible feeding tube that inserted into stomach abdominal wall in patients who will need long-term nutrient intake. The aim of this study analyze clinical characteristic children at time PEG placement as well determine indications, complications outcomes associated with Department Pediatrics...
Abstract Natural cardiac glycosides have positive inotropic heart effects but at high, toxic doses they can cause life-threatening arrhythmias. Here we present the first Croatian case of a 16-year-old girl who attempted suicide by eating dried oleander leaves, which contain natural glycosides, and her treatment with specific antidote. The presented an oedema uvula indicating local toxicity, severe bradycardia, first-degree atrioventricular block, drowsiness, vomiting. Having taken medical...
We assessed the methodological quality and transparency of all national clinical practice guidelines that were published in Croatia up until 2017 explored factors associated with their rating. An in-depth quantitative qualitative analysis was performed using rigorous methodology. evaluated a validated AGREE II instrument four raters; we used multiple linear regressions to identify predictors quality; two focus groups, including guideline developers, further explore development process. The...
Introduction: Like many healthcare providers, Critical Care providers require constant access to digital resources for their work. However, the increasing dependence on mobile phones has given rise "Nomophobia"- fear of being without one's phone. Despite its potential impact, there is a lack research nomophobia among critical care professionals. We aimed investigate prevalence as well magnitude this phobia professionals in settings. Methods: A cross-sectional study was conducted from...
Objective – Burn injuries (BI) are a great threat to children and significant therapeutic challenge. They demand prompt attention avoid infection scarring. The main goal of this paper is analyse the demographic clinical characteristics BI in treated Paediatric Intensive Care Unit (PICU), University Hospital Split (UHS).Patients Methods data patients with admitted PICU from 2010 through 2022 were collected retrospectively medical docu- mentation. subjects analysed stratified into groups...
BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) in children is a rare life-threatening syndrome, characterized by microangiopathic hemolytic anemia, thrombocytopenia with renal dysfunction, neurologic symptoms, and fever. TTP usually caused deficient activity of von Willebrand factor cleaving protease (ADAMTS13), due to either gene mutations or acquired via anti-ADAMTS13 autoantibodies. It can be triggered bone marrow solid organ transplantation, cardiothoracic-, abdominal-, orthopedic...
Atrezija jednjaka je anomalija koja hitnoćom, osjetljivim poslijeoperacijskim vođenjem i potrebom za dugotrajnim liječenjem odskače od ostalih anomalija. Cilj ovog istraživanja odrediti epidemiološke, demografske kliničke karakteristike bolesnika operiranihzbog atrezije te ih usporediti s ostalim relevantnim studijama. U vremenskom razdoblju siječnja 1991. do rujna 2014.retrospektivno su pregledane povijesti bolesti 46-ero operiranih zbog jednjaka. Podatke smo prikupili istraživanjempisanog...