A5085750405- Botulinum Toxin and Related Neurological Disorders
- Cerebral Palsy and Movement Disorders
- Stroke Rehabilitation and Recovery
- Myofascial pain diagnosis and treatment
- Facial Nerve Paralysis Treatment and Research
- Neurological disorders and treatments
- Facial Rejuvenation and Surgery Techniques
- Genetic Neurodegenerative Diseases
- Laser Applications in Dentistry and Medicine
- Nerve Injury and Rehabilitation
- Neurological Disorders and Treatments
- Shoulder Injury and Treatment
- Hereditary Neurological Disorders
- Temporomandibular Joint Disorders
- Migraine and Headache Studies
- Cancer Treatment and Pharmacology
- Hip disorders and treatments
- Pediatric Pain Management Techniques
- Dermatologic Treatments and Research
- Acupuncture Treatment Research Studies
- Musicians’ Health and Performance
- Orthodontics and Dentofacial Orthopedics
- Sympathectomy and Hyperhidrosis Treatments
- Musculoskeletal Disorders and Rehabilitation
- Healthcare Systems and Public Health
Saint Petersburg State Pediatric Medical University
1997-2025
Ministry of Health of the Russian Federation
2024
Objective. Multicenter retrospective analysis of the Russian experience in use AbobotulinumtoxinA injections for correction chronic sialorrhea various etiologies children. Material and methods. 608 (from 1 to 5 repeated injections) into salivary glands 226 patients aged 2.0 17.8 years (Me — 5.1 years) with neurological diseases neurodevelopmental disorders 12 centers. Results. In 180 (79.6%), was first drug used correct drooling. 177 (78.3%) children received combined body muscles...
A clinical case of consistent use botulinum toxin type (BTA) and azoximer bovhialuronidase (BA) in a 69-year-old patient who suffered an ischemic stroke (II) with right-sided hemiparesis is presented. BTA (incobotulotoxin) was injected under ultrasound control (ultrasound) into the muscles target pathological patterns at dose 500 units. After 3 weeks, navigation, BA 2 most fibrotic shoulder 3.000 IU (1.500 each). The effectiveness therapy monitored using modified Ashworth scale (MAS),...
Background. The similarity of tremor characteristics in patients with bruxism and muscular dystonia has been noticed clinical practice. During a search scientific databases, it was found that is topic interest but little studied. It similar to its characteristics, this may be confirmation the long discussed hypothesis research form dystonia. Research objective. To analyze compare focal dystonias. Material Methods. In single-center open comparative study on basis Central Institute Botulinum...
To access the efficacy and safety of first Russian botulinum toxin type A (Relatox) as a headache prophylaxis in adult with chronic migraine (CM).The randomized, one-blind, multicenter, active-controlled, parallel-group trial study involved 209 patients CM aged from 19 to 65 years. The were randomized injections - Relatox (n=101) or onabotulinumtoxinA Botox (n=108). duration was 16 weeks, which included five visits every 4 weeks. injected once into seven muscle groups head neck at dose...
Evaluation of the safety and effectiveness Relatox, botulinum toxin type A in patients with focal spasticity (FS) upper limb as a result cerebrovascular accident (CVA) or traumatic brain injury (TBI).
Spasticity treatment is one of the key aspects contemporary cerebral palsy (CP) rehabilitation that influences on effectiveness other methods. The paper presents first Russian document unites recommendations for BTA CP and could be used as guideline multilevel injections. consensus botulinum toxin A (BTA) spastic based international data results national studies. authors describe typical spasticity patterns in upper lower extremities, give recommended intervals (Abobotulinum A) dosages whole...
научный биометрический журнал, который знакомит читателя с клиническими рекомендациями и особенностями применения лекарственных вакцинных средств у детей, предоставляет исчерпывающую информацию о воздействии на плод, проводимых в
Total hip arthoplasty (THA) in school children with secondary arthritis is the least studied treatment orthopedic surgery. The need for THA arises much less often than adults, but a pressing problem. Indications joint replacement at age of 12–17 years include various etiologies such as dysplastic (congenital and paralytic), posttraumatic, infectious allergic (juvenile rheumatoid Bechterew’s disease), postinfectious (osteomyelitis tuberculosis joints joint) associated severe pain,...
Botulinum toxin type A (BTA) has taken a strong place in the rehabilitation of patients with impaired function mimic muscles both acute and late post-paralytic periods. Aim: to highlight main stages development botulinum therapy (BT) treatment dysfunctions Russia. Methods. Published data were searched electronic database Medline (PubMed) eLibrary. Results. The role BT dysfunctions, synkinesis (which can be interpreted clinically as secondary hemifacial spasm), lacrimation, dry eye syndrome,...
One of the modern components complex rehabilitation patients with spasticity is use botulinum toxin type A (BTA) preparations. International experience therapy in children spans more than 30 years. Abobotulinum has been used to treat since 1994. Clinical studies have shown high efficacy abobotulinumtoxin relieving lower and upper extremities cerebral palsy (CP) other disorders, which associated a significant increase muscle tone, thereby increasing motor skills achieving individual patient...
The purpose of the study. To evaluate relationship wakefulness and sleep bruxism with orofacial pain dynamics syndrome after injections botulinum neuroprotein type A. Material methods. A single-center open prospective interventional clinical trial at Central Institute Botulinum Therapy Topical Neurology involved 100 patients (90% women; age 19-39 years) an established diagnosis according to criteria developed by American Academy Sleep Medicine (AASM). Pain intensity was assessed using a...
<h3></h3> Спастичность при детском церебральном параличе — основное препятствие для полноценной локомоции. В основе любого ритмичного движения, в том числе ходьбы, лежит работа генератора центральных паттернов (CPG) нейронных цепей спинном мозге. CPG отсутствие надспинального контроля способен генерировать локомоторные паттерны самостоятельно, что может влиять на способность к перемещению как положительно, так и отрицательно. Выполнение двигательных задач, таких ходьба, бег плавание,...
Background: early treatment using botulinum toxin type A (BTA) postpones or even prevents contractures and osteoarticular deformations and, therefore, surgical interventions in children with cerebral palsy (CP). Expansion of age groups conditions to prescribe BTA is the primary trend current studies. Aim: assess safety efficacy Relatox® aged 2–6 years spastic CP. Patients Methods: this simple blind randomized comparative study (2018–2019) enrolled 100 According protocol, (n=51) reference...