A5016437957- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Eosinophilic Esophagitis
- Asthma and respiratory diseases
- Exercise and Physiological Responses
- Contact Dermatitis and Allergies
- Biomedical and Chemical Research
- Health and Medical Studies
- Urticaria and Related Conditions
- Sports Science and Education
- Probiotics and Fermented Foods
- IL-33, ST2, and ILC Pathways
- Workplace Health and Well-being
Charité - Universitätsmedizin Berlin
2021-2023
Freie Universität Berlin
2022-2023
Humboldt-Universität zu Berlin
2022-2023
Peanut and tree nut allergies are common in childhood often severe nature. The clinical picture shows a wide variety of symptoms.To analyze the distribution symptoms severity during oral food challenges (OFC) children.Analysis 1.013 prospectively recorded, positive OFCs with peanut (n = 607), hazelnut 266), walnut 97), cashew 43). Symptoms were categorized as immediate-type skin, gastrointestinal, upper lower respiratory, cardiovascular symptoms, eczema exacerbation. Symptom treatment...
Abstract Background Up to 8% of all children in industrialized countries suffer from food allergies, whereas with atopic eczema are affected considerably more frequently. In addition, the type and starting time weaning foods seem influence development allergies. However, data interventional studies on controversial. The aim this randomized-controlled clinical trial is investigate, whether an early introduction hen's egg (HE), cow’s milk (CM), peanut (PN), hazelnut (HN) can reduce risk for...
Abstract Background IgE‐mediated food allergy is the result of an aberrant immune response involving interaction a allergen with its specific IgE bound to FcɛRI, high affinity receptor, on mast cells. Allergen‐specific also binds soluble binding factors, but, their expression and role in not well characterized. Here, we assess prevalence relevance factors tolerance. Methods We measured serum levels four that is, galectin‐3, galectin‐9, FcɛRI (sFcεRI) CD23 (sCD23) 67 adults sensitized peanut...
Peanut allergy is a frequent cause of food and potentially life-threatening. Within this interdisciplinary research approach, we aim to unravel the complex mechanisms peanut allergy. As first step were applied in an exploratory manner analysis allergic versus non-allergic controls.
Abstract Background Peanuts (PN) and tree nuts (TN) are among the most frequent elicitors of food allergy can lead to life-threatening reactions. The current advice for allergic patients is strictly avoid offending independently their individual threshold level, whereas sensitized without symptoms should frequently consume (re-)development allergy. aim this trial investigate (I) whether consumption low allergen amounts below may support natural tolerance development (II) what extent regular...
Background: In order to determine tolerance development in hen’s egg (HE) allergic children, international guidelines recommend an oral food challenge after 6-24 months. This study aimed assess whether parents follow this advice and factors that influence their decision. Methods: A follow-up of 158 challenge-proven HE children was performed. Families who did not come a rechallenge were contacted by phone standardized survey relating the current allergy status conducted. Logistic regression...
Background: Allergic diseases are the most prevalent chronic childhood resulting in a massive societal and economic burden for community significant reduction of health-related quality life (HRQoL) affected families. The project CHAMP (CHildhood Allergy tolerance: bioMarkers Predictors) was funded 2017 by German Federal Ministry Education Research. Methods: investigates determinants different allergic from birth to adolescence identify clinically relevant biomarkers predicting onset,...