A5022067503- Stress Responses and Cortisol
- Cardiac Health and Mental Health
- Heart Rate Variability and Autonomic Control
- Tryptophan and brain disorders
- Exercise and Physiological Responses
- Obstructive Sleep Apnea Research
- Mindfulness and Compassion Interventions
- Dementia and Cognitive Impairment Research
- Complementary and Alternative Medicine Studies
- Sleep and related disorders
- Blood Pressure and Hypertension Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Neuroscience of respiration and sleep
- Sleep and Wakefulness Research
- Receptor Mechanisms and Signaling
- Heart Failure Treatment and Management
- Health, psychology, and well-being
- Cancer survivorship and care
- Psychological Well-being and Life Satisfaction
- Religion, Spirituality, and Psychology
- Cardiovascular and exercise physiology
- Neuropeptides and Animal Physiology
- Hormonal Regulation and Hypertension
- COVID-19 and Mental Health
- Neuroinflammation and Neurodegeneration Mechanisms
University of California, San Diego
2016-2025
Human Longevity (United States)
2021-2025
University of California San Diego Medical Center
2000-2024
University of San Diego
2022
American Orchid Society
2021
University of Zurich
2010-2020
University Hospital of Zurich
2020
La Jolla Alcohol Research
2009-2019
University of South Florida
2019
ORCID
2019
Background: Although mindfulness meditation interventions have recently shown benefits for reducing stress in various populations, little is known about their relative efficacy compared with relaxation interventions. Purpose: This randomized controlled trial examines the effects of a 1-month versus somatic training as to control group 83 students (M age = 25; 16 men and 67 women) reporting distress. Method: Psychological distress, positive states mind, distractive ruminative thoughts...
Thirty-eight individuals (mean age: 34.8 years old) participating in a 3-month yoga and meditation retreat were assessed before after the intervention for psychometric measures, brain derived neurotrophic factor (BDNF), circadian salivary cortisol levels, pro- anti-inflammatory cytokines. Participation was found to be associated with decreases self-reported anxiety depression as well increases mindfulness. As hypothesized, plasma levels of BDNF magnitude awakening response (CAR) also...
Background: The prevalence of liver disorders and metabolic syndrome has increased among youth. Glyphosate, the most widely used herbicide worldwide, could contribute to development these conditions. Objective: We aimed assess whether lifetime exposure glyphosate its degradation product, aminomethylphosphonic acid (AMPA), is associated with elevated transaminases young adults. Methods: conducted a prospective cohort study (n=480 mother–child dyads) nested case–control (n=60 cases 91...
Abstract Objective : The concept of symptom clusters is relatively new in cancer patients' management. This study, which spanned four cycles chemotherapy, combined three commonly seen pre‐treatment symptoms patients (i.e. sleep disturbances, fatigue and depression) into one cluster, to explore the associations between cluster categories longitudinal profiles these same during chemotherapy. Methods was a prospective study. Seventy‐six women with newly diagnosed stage I–III breast cancer,...
Obstructive sleep apnea (OSA) is associated with recurrent episodes of nocturnal hypoxia and increased risk for development systemic hypertension. Prior studies have been limited, however, in their ability to show reduction blood pressure after continuous positive airway (CPAP) therapy, the effect supplemental oxygen alone on OSA has not evaluated. We performed a randomized, double-blind, placebo-controlled study comparing effects 2 weeks CPAP versus sham-CPAP 24-hour ambulatory 46 patients...
Low-intensity light therapy (LILT) appears to be working through newly recognized photoacceptor systems. The mitochondrial electron transport chain has been shown photosensitive red and near-infrared (NIR) light. Although the underlying mechanisms have not yet clearly elucidated, photostimulation increase ATP production cause transient increases in reactive oxygen species (ROS). In some cells, this process participate reduction/oxidation (redox) signaling. Redox are known involved cellular...
Objective: The literature provides evidence of a strong relationship between greater stress and memory loss, but few studies have examined this with both variables measured over time. authors sought to determine the prospective association subjective objective measures chronic rate decline in cognitively normal mildly impaired older adults. Method: This longitudinal study was conducted at university research center included 61 subjects 41 mild cognitive impairment (ages 65–97). Fifty-two...
To determine whether objective measures of sleep correlate with plasma levels the proinflammatory cytokine interleukin (IL)-6 and procoagulant marker fibrin D-dimer in caregivers patients dementia.Cross-sectional study.Subjects' homes.Sixty-four community-dwelling spousal (69% women, mean age+/-standard deviation 72+/-9) 36 sex-matched noncaregiving controls.All participants underwent in-home full-night polysomnography. Demographic lifestyle factors, depression, diseases, medication that...
<i>Background:</i> Elderly individuals who provide care to a spouse suffering from dementia bear an increased risk of coronary heart disease (CHD). <i>Objective:</i> To test the hypothesis that Framingham CHD Risk Score would be higher in caregivers relative non-caregiving controls. <i>Methods:</i> We investigated 64 providing in-home for their with Alzheimer’s and 41 gender-matched All subjects (mean age 70 ± 8 years, 75% women, 93% Caucasian) had...
Biofield therapies are noninvasive in which the practitioner explicitly works with a client's biofield (interacting fields of energy and information that surround living systems) to stimulate healing responses patients. While practice has existed Eastern Western cultures for thousands years, empirical research on effectiveness is still relatively nascent. In this article, we provide summary state evidence number different clinical conditions. We note specific methodological issues need be...
REPORT insomnia symptoms. 1,2 There is also evidence suggesting that breast cancer patients constitute the subgroup of most at risk for experiencing sleep difficulties. 3,4 In addition to resulting in restless (i.e., increased activity during night), and its treatment may reduce daytime activity.Although data are rather sparse, there some suggest have disturbed circadian rhythms.6][7][8][9] But few examined variables before patients.Some on rhythms be altered even prior initiation...
Background. Curcuma longa (common name: turmeric) and one of its biologically active constituents, curcumin, have received increased clinical attention. Insufficient data exist on the effects curcumin turmeric gut microbiota such studies in humans are lacking. Methods. Turmeric tablets with extract piperine (Bioperine) (n = 6), Bioperine 5), or placebo 3) were provided to healthy human subjects subsequent changes determined by 16S rDNA sequencing. Results. The number taxa detected ranged...
Fatigue and sleep disturbances are two of the most common distressing symptoms cancer patients. A relationship between was reported in symptom cluster studies; however, only subjective measurements were examined studies cross-sectional. In this study women with breast undergoing chemotherapy, we explored longitudinal fatigue measured both subjectively objectively.Prospective study. Data collected at 7 time points: before (baseline) during 3 weeks cycle 1 4 chemotherapy.Ninety-seven newly...
The science of meditation has grown tremendously in the last two decades. Most studies have focused on evaluating clinical effectiveness mindfulness-based interventions, neural and other physiological correlates meditation, individual cognitive emotional aspects meditation. Far less research been conducted more challenging domains to measure, such as group relational, transpersonal mystical, difficult meditation; anomalous or extraordinary phenomena related post-conventional stages...