Analysis of blood platelets encounters a number different preanalytical issues, which greatly decrease the reliability and accuracy routine clinical analysis.

<p><strong>Aim:</strong> The study aimed to determine the predictive value of retrograde pressure (RP) indicators and cerebral oxygenation in evaluation ischemic brain damage during carotid endarterectomy (CEA).<br /><strong>Methods:</strong> This nonrandomized, prospective pilot included 87 patients with asymptomatic stenosis greater than 70% who underwent under general anesthesia. Brain tolerance ischemia was determined by measuring evaluating RP (∆rSO2)...

NaCl 7.2%/6% hydroxyethyl starch (HES) 200/0.5 (HSH) has shown its beneficial effects in cardiac surgery and immunomodulatory values experiment human studies. However, there is concern regarding detrimental renal of chloride HES the intensive care setting.The objective this study was to evaluate influence HSH on kidney integrity level inflammatory mediators on-pump coronary artery bypass patients.This a single-center, prospective, randomized, single-blind pilot study.This work performed at...

The aim of this study was to test the hypothesis that use inhalational anesthesia leads higher suppression cell-mediated immunity compared total intravenous in patients undergoing kidney cancer surgery under combined low thoracic epidural analgesia and general anesthesia.Patients were randomly allocated either propofol-based (intravenous anesthetic) or sevoflurane-based (volatile group with 10 each group, along both groups. Amounts natural killer (NK) cells, T lymphocytes, lymphocyte...

Background. Immunological and infectious safety of blood components is considered to be a key condition for high-quality transfusion therapy. The progress filtration methods contributes the development validation residual leukocyte control in products. aim study was compare efficiency flow cytometer with hematology analyzer counting leukocytes products Methods. In this study, we compared two analytical instruments 191 plasma samples: (Navios Beckman Coulter) LeukoSure commercial reagent kit...

Background. The aim of study was to test the hypothesis that early enteral nutrition (EN) with calorie-dense and protein rich formula improves energy delivery in critically ill cardiac patients. Methods. Prospective randomized pilot 40 ventilated adult patients undergoing elective surgery use cardiopulmonary bypass receiving inotropic support postoperatively. Patients were receive either standard isocaloric (1000 Kcal/L 38 g/L protein) EN (n = 20) or protein-rich (1300 66.7 20). Results....

Objective: to study the impact of goal-oriented infusion therapy using balanced salt solution, 4% succinylated gelatin, and 6% hydroxyethyl starch 130/0.42 solution on pulmonary extravascular water levels in coronary heart disease patients operated under extracorporeal circulation. Materials methods. A prospective, randomized, single-blind clinical investigating was conducted patents The hemodynamic target global end-diastolic volume index which maintained range from 680 850 ml/m2. Pulmonary...

Abstract We propose a calibration‐free method to determine the number of receptors per cell, as well direct and reverse reaction rate constants for single receptor. The is based on analysis temporal evolution cells mean fluorescent intensity measured by flow cytometer during ligand–receptor (antigen–antibody) binding under conditions their comparable concentrations. developed kinetic approach accounting both delay between dilution measurement practical duration itself. was applied thenumber...

We examined 324 patients with various oncological diseases (157 prostate cancer, 54 - lung 47 uterine 42 cervical cancer and 24 breast cancer) 391 relatively healthy donors. investigated the frequency of key polymorphisms folate metabolism genes (MTHFR: 677 C>T (Ala222Val); MTHFR: 1298 A>C (Glu429Ala); MTR: 2756 A>G (Asp919Glu); MTRR: 66 (Ile22Met)). Analysis revealed no differences in all gene alleles between All genotypes cycle were not associated risk for development diseases.

We present in this paper results of assessment functional state right ventricular (RV) myocardium 38 patients with acute pulmonary embolism (PE) before and after endovascular recanalization arteries supplemented thrombolytic therapy. According to echocardiography data RV dysfunction was detected 60.5% cases, while an elevated concentration brain natriuretic peptide (BNP) blood plasma observed all patients. None the had level troponin I. An increased BNP normal PE indicative a hidden due its...

A pilot double-blind, placebo-controlled, randomized study The aim of this was to evaluate the efficiency perioperative administration glutamine preserve intestinal integrity in patients undergoing cardiac surgery. 24 scheduled for elective coronary artery bypass surgery under cardiopulmonary were included prospective, randomized, double-blind placebo controlled study. 12 receive (20% solution N(2)-L-alanyl-L-glutamine) 0.4 g/kg a day, while remaining received an equivalent dose (0.9% NaCl)....

Abstract Background This study was conducted to test the hypothesis that phosphocreatine (PCr), administered intravenously and as cardioplegia adjuvant in patients undergoing cardiac surgery with prolonged aortic cross clamping cardiopulmonary bypass (CPB) time, would decrease troponin I concentration after surgery. Methods In this randomized, double-blind, placebo-controlled pilot we included 120 double/triple valve repair/replacement under department of a tertiary hospital. The treatment...

Goal of the study: to identify predictors continuous hospital stay in adult patients with acquired valvular disease, operated hypothermic and normothermic cardiopulmonary bypass due definitive repair disease. Materials methods: 140 who had surgical treatment disease use were randomly divided into two similar groups where bypasses used. Peri-operative concentration NT-proBNP, clinical course post-operative period, morbidly mortality assessed. Results. No confident difference was observed...

научный биометрический журнал, который знакомит читателя с клиническими рекомендациями и особенностями применения лекарственных вакцинных средств у детей, предоставляет исчерпывающую информацию о воздействии на плод, проводимых в

Purpose. This study was aimed at examining the infl uence of thrombophilic conditions on pulmonary embolism (PE) and effi cacy thrombolytic therapy. Materials methods. The effects haemostatic disorders frequency recurrent PE, phlebothrombosis inferior vena cava thrombosis were studied in 70 patients with acute massive PE. Results. Hematogenic thrombophilia detected 25,7 % patients. It found that fi lter observed more frequently hematogenic than unknown etiology. Conclusions. proved...

Background and aims: In pediatric cardiac surgery, early sepsis diagnosis assessment of severity is extremely difficult, due to the nature postoperative period these special group patients. The use routine biomarkers such a procalcitonin C-reactive protein levels has several limitations in infants after surgery with CPB. Aims: goal was study sensitivity specificity, positive negative prognostic value neutrophil?D64-index as an diagnostic marker neonates cardiopulmonary bypass (CPB). Methods:...

Purpose. Make a comparative assessment of supportive methods myocardial revascularization in ischemic heart disease patients with low left ventricular ejection fraction (<35 %) conducted under CPB cardioplegic cardiac arrest and on beating combined intraoperative use IABP or levosimendan. Materials methods. The study included 90 coronary artery <35 %, which was performed CABG normothermic CPB. Patients were randomized into 4 groups: IABP+CP (CPB cardioplegia IABP) (n=30), IABP+CPB (beating...