A5071868978- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Anesthesia and Neurotoxicity Research
- Neonatal and Maternal Infections
- Mechanical Circulatory Support Devices
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Neonatal Respiratory Health Research
- Cardiac and Coronary Surgery Techniques
- Airway Management and Intubation Techniques
- Hemodynamic Monitoring and Therapy
- Infective Endocarditis Diagnosis and Management
- Voice and Speech Disorders
- Nosocomial Infections in ICU
- Neurotransmitter Receptor Influence on Behavior
- Cardiac Valve Diseases and Treatments
- Pneumothorax, Barotrauma, Emphysema
- Bacterial Identification and Susceptibility Testing
- Cardiac Arrhythmias and Treatments
- Vascular anomalies and interventions
- Treatment of Major Depression
- Infrared Thermography in Medicine
- Diphtheria, Corynebacterium, and Tetanus
- Central Venous Catheters and Hemodialysis
- Cardiovascular and Diving-Related Complications
- Human Health and Disease
Peoples' Friendship University of Russia
2023-2025
National Medical and Surgical Center named after N.I. Pirogov
2024
Medicina
2023
Meshalkin National Medical Research Center
2011-2020
Scientific Research Institute of Biochemistry
2005
Corticosteroids are widely used in pediatric cardiac surgery to blunt systemic inflammatory response and reduce complications; nevertheless, their clinical efficacy is uncertain.To determine whether intraoperative administration of dexamethasone more effective than placebo for reducing major complications mortality during surgery.The Intraoperative Dexamethasone Pediatric Cardiac Surgery was an investigator-initiated, double-blind, multicenter randomized trial that involved 4 centers China,...
Relevance. Healthcare-associated infections (HAIs) are a significant problem in intensive care units. They contribute to increased mortality, lengthen hospital stays and increase treatment-related costs. The aim of the study was evaluate effectiveness reducing microbial background cross-transmission pathogenic microorganisms associated with provision medical units surgical systemic use Alpha‑06A pulsed ultraviolet system “Areal” device (Scientific Production Enterprise «Melitta», Russia)....
The volume of the left atrium is one key factors associated with both development primary atrial fibrillation and its progression. Open communication considered as a factor predisposing to dilation remodeling heart cavities. We present clinical case endovascular closure an open oval window in patient persistent form AF, moderately reduced ventricular ejection fraction, who had previously undergone radiofrequency ablation, manifestations failure. A 58-year-old was hospitalized November 2019...
Providing medical care based on a patient-centered medicine model supposes close collaboration with patients and their families partnership. The development of action plan aimed implementation comfortable conditions for the child during surgery anesthesia, considering his needs age characteristics, is topical issue in pediatrics. This article provides an organizational anesthesia child-friendly environment covers all main stages patient's stay hospital.
BACKGROUND: Currently, more and laser surgeries are performed in pediatric ophthalmology. Expansion of indications for vision correction children entails the increase number patients poses new specific tasks anesthesiology. Solution these problems is currently at stage active clinical search. AIM: To propose a safe, reproducible controllable method anesthesiological support ophthalmic which would ensure complete immobility eyeball during intervention patient’s rapid awakening after surgery....
The objective was to present the experience of airway management algorithm in patients with different localization stenosis during circular tracheal resection. Materials and methods. retrospective analysis included 84 grade II cicatricial who underwent resection at period from 2018 2023. were divided into two groups: group 1 long-segment 2 short-segment (39 45 patients, respectively). age 43 years [28–55] versus 48 [35–61] (p = 0.19). groups comparable terms main parameters: gender, ratio...
INTRODUCTION: Pelizeaus–Merzbacher disease is an orphan disorder caused by a mutation in the PLP1 gene, linked with X chromosome. Its incidence 1.4–1.9 per 100 thousand people general population. The hereditary leukodystrophy which predominantly affects central nervous system (CNS) and characterized sharp decrease or absence of myelin sheaths white matter areas CNS. Impaired neuromuscular conduction, reduced muscle tone may lead to scoliotic spinal deformation including that very severe...
This review addressed the issues of strategies for diagnosis and management patients undergoing acute aortic dissection complicated by abdominal malperfusion syndromes. These complications remain a common unresolved task following surgery. The clinical course accompanied ischaemia syndrome are com Abdominal as complication type A dissection.Received 26 August 2019. Revised 11 November Accepted 12 2019.Funding: study did not have sponsorship.Conflict interest: Authors declare no conflict interest.
The objective: to assess the accuracy of cardiac output measurement by ultrasonic monitor ( USCOM ) versus echocardiography ECHO in children after surgery. Subjects and methods: A prospective observational trial was conducted (288 patients were assessed for eligibility, data from 88 analyzed). Cardiac measured . Results. age 305 ± 177 days. , 1.310 0.605 [1.182; 1.438] L/m in, while one made 1.298 0.608 [1.169; 1.427] in. ANOVA demonstrated no statistically significant difference p = 0.89)....
Background and aims: In pediatric cardiac surgery, early sepsis diagnosis assessment of severity is extremely difficult, due to the nature postoperative period these special group patients. The use routine biomarkers such a procalcitonin C-reactive protein levels has several limitations in infants after surgery with CPB. Aims: goal was study sensitivity specificity, positive negative prognostic value neutrophil?D64-index as an diagnostic marker neonates cardiopulmonary bypass (CPB). Methods:...
Sepsis and its consequences continue to be a major cause of morbidity mortality in the intensive care unit (ICU). The evidence that endogenous mediators actually mediate an individual response infection has led development different approaches assess impact each person on course disease. role genetic background susceptibility human inflammatory amplitude are determined by variability genes encoding which produced during inflammation. Pro-and anti-inflammatory reactions influence outcomes...
Currently gram-negative bacteria are recognized as the most problematic pathogens. The authors studied incidence of bacteremia caused by microflora and its sensitivity to antibiotics in patients who underwent cardiac surgery. We analyzed results blood tests over a period 5 years, from 2007 2011. During this period, 216 strains were identified. Enterobacteria accounted for 57.4% (124) structure flora, while 42.6% (92) glucose non-fermentative bacteria. prevailing pathogens detected when...
Klebsiella pneumoniae is one of the leading agents nosocomial infections (NI). In Russia, third in frequency gram-negative pathogen NI. For a long time major clinically relevant mechanisms acquired resistance to K. multidrug caused by extended spectrum -lactamase production (ESBL). Carbapenems show greatest action ESB. However, now there exist registered strains K.pneumoniae resistant carbapenems. connection with this 2008 we conducted prospective study on young children being treated at...
Aim. To evaluate the results of vacuum therapy and closed irrigation drainage (CID) technique for treatment postoperative sternomediastinitis in infantsMethods. This single-institution retrospective study included 69 patients diagnosed with from 2008 to 2018. Patients were divided into two groups: those treated using vacuum-assisted closure (VAC; n = 29) CID (n 40). After propensity score matching, a total 25 infants each group.Results. Age, gender, weight, body surface area, Risk Adjustment...
97 neonates were included in this prospective observational study. While using the exclusion criteria, two groups without demographic differences formed: first group 35 patients with blood loss greater than 10 ml/kg 4 hours postoperatively, second one consisted of 46 who did not have such loss. Hemostatic standard tests and thromboelastography performed before surgery, immediately after surgery 24 it. As a result, detailed description changes hemostasis perioperative period newborns CHD was...
BACKGROUND: Surgeries to correct scoliotic spinal deformity (posterior corrective transpediculocorporal fusion) are classified as highly traumatic, accompanied by significant blood loss, and require reliable venous access. Central vein catheterization is an important part of patient management a successful safe procedure.
 AIM: To evaluate the effectiveness ultrasound navigation during central in patients with severe super-severe deformity.
 MATERIALS AND METHODS: A single-center...
Background . Brain neuroimaging studies provided information about the neurobiological effects of narcotic substances, and established mechanisms their systematic use, as well important subjective experience behavior people with drug addiction, including struggle for recovery. Until recently, five main methods brain were considered – structural magnetic resonance imaging (MRI), functional MRI (fMRI), spectroscopy (MRS), positron emission tomography (PET) single-photon computed (SPECT). These...
Background. Methamphetamine negatively affects microglia, reducing the reuptake of dopamine, which leads to neurotoxicity and an increase in brain temperature. In order monitor dynamics cerebral temperature, radiothermographs that register thermal radiation deep tissues head (MR thermometry) can be used. The purpose research: study temperature balance acute methamphetamine poisoning.Materials methods. All groups consisted dextral (right-handed) males. control group (group I) included 30...