A5063473925- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiovascular and Diving-Related Complications
- Acute Myocardial Infarction Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Antiplatelet Therapy and Cardiovascular Diseases
- Vascular Procedures and Complications
- Aortic Disease and Treatment Approaches
- Peripheral Artery Disease Management
- Cardiovascular Disease and Adiposity
- Venous Thromboembolism Diagnosis and Management
- Healthcare Systems and Public Health
- Cardiac and Coronary Surgery Techniques
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Kawasaki Disease and Coronary Complications
- Breast Cancer Treatment Studies
- Acute Ischemic Stroke Management
- Coronary Artery Anomalies
- Cancer Risks and Factors
- Cardiac Structural Anomalies and Repair
- Rheumatoid Arthritis Research and Therapies
- Cardiac tumors and thrombi
National Medical Research Center of Cardiology
2018-2024
Moscow Clinical Scientific Center
2024
Ministry of Health of the Russian Federation
2023
Institute of Experimental Cardiology
2012-2022
State Research Center of the Russian Federation
2019
Federal State Budgetary Institution Russian Scientific Center of Roentgenoradiology
2018
Erasmus University Rotterdam
2017
Background: Left atrial appendage occlusion with WATCHMAN has emerged as viable alternative to vitamin K antagonists in randomized controlled trials. Evaluating real-life clinical outcomes fibrillation patients receiving the left closure technology was designed collect prospective multicenter of thromboembolic events, bleeding, and mortality for implanted a routine daily practice. Methods: One thousand twenty implant procedure were prospectively followed 47 centers. indication based on...
Background: Left atrial appendage closure is an established therapy in patients with fibrillation. Although device-related thrombosis (DRT) relatively rare, it potentially linked to adverse events. As data on DRT characteristics, outcome, and treatment regimen are scarce, we aimed assess these questions a multicenter approach. Methods: One hundred fifty-six the diagnosis of after left were included multinational EUROC-DRT registry. Baseline characteristics clinical echocardiographic data....
Improvements in drug-eluting stent design have led to a reduced frequency of repeat revascularisation and new biodegradable polymer coatings may allow shorter duration dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI).The Improved Drug-Eluting for All-comers Left Main (IDEAL-LM) study aims investigate long-term clinical outcomes implantation platinum-chromium everolimus-eluting (BP-PtCr-EES) followed by 4 months DAPT compared durable cobalt-chromium...
Continuous improvements in stent technology make percutaneous coronary intervention (PCI) a potential alternative to surgery selected patients with unprotected left main artery (uLMCA) disease. The optimal duration of dual antiplatelet therapy (DAPT) these remains undetermined, and addition, new designs using bioabsorbable polymer might allow shorter DAPT.IDEAL-LM is prospective, randomized, multicenter study that will enroll 818 undergoing uLMCA PCI. Patients be randomized 1:1 fashion...
Distal coronary artery embolism (DCAE) is a serious complication of percutancous intervention (PCI). causes significant reduction or even blockage myocardial perfusion, despite the fact that blood flow in occluded segment infarct-related restored. According to various sources, incidence distal embolization associated with PCI about 25%. Various techniques, both invasive and non-invasive, have been developed for identifying embolism. DCAE during prevented help different devices, among which...
Background. Despite the enormous benefits of radial access, this route is associated with a risk artery occlusion (RAO). Objective. We compared incidence RAO in patients undergoing transradial coronary angiography and intervention after short versus prolonged hemostasis protocol. Also we assessed efficacy rescue 1-hour ipsilateral ulnar compression if was observed hemostasis. Material Methods. Patients referred for elective procedures were eligible. After 6 F sheath removal, randomized to (3...
А clinical case of a young patient with recurrent ischemic strokes is presented. The problems diagnostic embolic are discussed. We set out the algorithm for identifying patients, in whom patent foramen ovale most probable cause stroke. Detailed consideration imaging methods possibility included. Hypothesis source cardioembolism from Recommendations secondary prevention stroke, associated ovale, provided. also considered issues antithrombotic treatment.
Purpose. This multicenter, prospective registry evaluated the comparative safety and efficacy of left atrial appendage occlusion (LAAO) using Watchman device (WD) Amplatzer Cardiac Plug (ACP) in patients with nonvalvular fibrillation (NVAF) real-world clinical practice Russia. Methods. The study included data from 200 consecutive NVAF ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"><mn>66.8</mn><mo>±</mo><mn>7.8</mn></math> years, 44.5% female, median CHA2DS2VASc 4, HAS-BLED 3)...
Purpose: to compare rates of access site complications at early (after 4 hours) and traditional 24 removal a compression bandage after diagnostic transradial (TR) coronary angiography (CA) in patients not receiving anticoagulants. Materials methods. We included into this study 392 (mean age 63±8.7 years, 62.8% men) who underwent angiography. Patients were divided 2 groups. In group 1 (n=221) was removed from puncture hours procedure with subsequent control radial artery patency using...
The volume of the left atrium is one key factors associated with both development primary atrial fibrillation and its progression. Open communication considered as a factor predisposing to dilation remodeling heart cavities. We present clinical case endovascular closure an open oval window in patient persistent form AF, moderately reduced ventricular ejection fraction, who had previously undergone radiofrequency ablation, manifestations failure. A 58-year-old was hospitalized November 2019...
The article discusses aspects of the restoration psychoemotional sphere in patients suffering a stroke associated with an open foramen ovale, who underwent endovascular occlusion at stationary stage. It was revealed that due to their negative social perceptions recovery after stroke, they are afraid return active lifestyle treatment. possibility introducing consultative conversations correction create positive way life for which will contribute sphere, is considered.
Aim. To study 12-month dynamics of residual shunt (RS) closure after endovascular patent foramen ovale (PFO) closure. Material and methods. We analyzed the data 80 patients who underwent PFO at Chazov National Medical Research Center for Cardiovascular Diseases in period 2018-2023. All a full range examinations accordance with current clinical guidelines. The severity RS immediately occluder implantation, as well 1, 6 12 months post-intervention assessment was based on transesophageal...
Purpose of the study. To study effect prophylactic antibiotic therapy on course postoperative period in patients undergoing endovascular closure patent foramen ovale (PFO). Material and methods. The included 276 who were submitted to PFO. follow-up duration was 12 months. Depending divided into 2 groups - those did not receive received (115 161 patients, respectively). Results. Cephalosporins prescribed as therapy, presence allergic reactions they replaced by glycopeptides. In total, 1 drugs...
Aim. To study the effect of endovascular closure patent foramen ovale (PFO) on severity symptoms migraine attacks in patients with a history aura. Materials and Methods. We analyzed data 74 aura who underwent PFO for period from 2018 to 2022 at E.I. Chazov National Medical Research Center Cardiology. All examinations that complied clinical recommendations. The presence was determined through patient interview, previous hospital history, confirmed by neurologist. assessed using MIDAS...
INTRODUCTION: Platypnea is defined as initiation or worsening of dyspnea when a patient moves from supine to sitting standing position. This condition usually accompanied by orthodeoxia, rather rapidly (within 2–3 minutes) developing hypoxemia triggered this change in posture. review focuses on the pathophysiological mechanisms, diagnostic approaches and methods surgical treatment platypnea–orthodeoxia syndrome (POS) such cardiac pathology patent foramen ovale (PFO). AIM: To conduct an...
Introduction . In order to prevent thrombotic complications after endovascular closure of patent foramen ovale (PFO), dual antiplatelet therapy (DAPT) is prescribed with a switch acetylsalicylic acid monotherapy. These drugs increase the risk bleeding, while early withdrawal can lead recurrent ischemic stroke (IS) and transient attack (TIA). The effective safe duration DAPT has not been accurately established due small evidence base. Aim To compare efficacy safety long-term shortened (AAT)...
Background. Administration of antiplatelet therapy (APT) is the basis for prevention thrombotic complications after endovascular closure patent foramen ovale (PFO). The 2018 European consensus document on management patients with PFO recommended long-term APT. Dual was prescribed 6 months followed by acetylsalicylic acid (ASC) monotherapy up to 5 years. Subsequent clinical trials demonstrated a trend towards shorter APT due risk ASC-associated bleeding. In 2022, SCAI society limiting...
Aim. To study the in-hospital outcomes of patients with residual shunt (RS) through occluder and identify predictors its formation after endovascular patent foramen ovale (PFO) closure. Material methods. We analyzed data 276 who underwent PFO closure for period 2018-2023 at Chazov National Medical Research Center. All a scope examinations that complied clinical recommendations. RS in postoperative was assessed based on Transesophageal echocardiogram bubble study. Univariate regression...