A5017502812- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Corrosion Behavior and Inhibition
- Titanium Alloys Microstructure and Properties
- Magnesium Alloys: Properties and Applications
- Nanoparticles: synthesis and applications
- Anodic Oxide Films and Nanostructures
- Graphene and Nanomaterials Applications
- Electrodeposition and Electroless Coatings
- Aluminum Alloys Composites Properties
- Orthopedic Infections and Treatments
- Laser-Ablation Synthesis of Nanoparticles
- Advanced Drug Delivery Systems
- Metal and Thin Film Mechanics
- High-Temperature Coating Behaviors
- Metallic Glasses and Amorphous Alloys
- Diamond and Carbon-based Materials Research
- Dental materials and restorations
- Boron and Carbon Nanomaterials Research
- Conducting polymers and applications
- Aluminum Alloy Microstructure Properties
- Concrete Corrosion and Durability
- Shape Memory Alloy Transformations
- Bacterial biofilms and quorum sensing
- Nanoparticle-Based Drug Delivery
Delft University of Technology
2013-2024
California Maritime Academy
2019
Gheorghe Asachi Technical University of Iași
1997
Exploiting the synergistic antibacterial behavior of Ag and Cu nanoparticles in self-defending implants.
Abstract Development of synthetic bactericidal surfaces is a drug‐free route to the prevention implant‐associated infections. Surface nanotopographies with specific dimensions have been shown kill various types bacterial strains through mechanical mechanism, while regulating stem cell differentiation and tissue regeneration. The effective ranges required simultaneously achieve both aims are in <200 nm range. Here, nanoscale additive manufacturing (=3D printing) technique called electron...
The antibacterial biofunctionality of bone implants is essential for the prevention and treatment implant-associated infections (IAI). In vitro co-culture models are utilized to assess this study bacteria-host cell interactions at implant interface, aiding our understanding biomaterial immune response against IAI without impeding peri-implant tissue regeneration. This paper reviews existing together with their characteristics, results, clinical relevance. A total 36 studies were found...
Drug delivery systems (DDS) based on poly (lactide-co-glycolide) (PLGA) microspheres and nanospheres have been separately studied in previous works as a means of delivering bioactive compounds over an extended period time. In the present study, two DDS having different sizes PLGA spheres were compared morphology, drug (dexamethasone) loading efficiency release kinetics order to investigate their feasibility with regard production medical combination devices for orthopedic applications. The...
The effects of substrate composition on oxide layer properties following plasma electrolytic oxidation under similar conditions have been evaluated for α-cpTi, α/β-Ti6Al7Nb, β-Ti35Zr10Nb and β-Ti45Nb alloys. All oxidised surfaces revealed enhanced wettability, surface free energy roughness relative to the non-oxidised surfaces. Nevertheless, resultant oxides differed with respect average pore size, pores density, chemistry phase composition. β-titanium alloys developed a larger size lower...
The holy grail of orthopedic implant design is to ward off both aseptic and septic loosening for long enough that the outlives patient. Questing this feasible only if biomaterials possess a list functionalities enable them discharge onerous task permanently replacing native bone tissue. Here, we present rationally designed additive manufacturing (AM) topologically ordered porous metallic biomaterial made from Ti-6Al-4V using selective laser melting packs most (if not all) required into...
Prevention of biomaterial-associated infections (BAI) remains a challenging problem, in particular due to the increased risk resistance development with current antibiotic-based strategies.Metallic orthopaedic devices, such as non-cemented implants, are often inserted under high mechanical stress.These implants cannot be protected by e.g.antibiotic-releasing bone cement or other antimicrobial approaches, use bioactive glass.Therefore, order avoid abrasion during implantation procedures, we...