A5103063269- Animal Nutrition and Physiology
- Genetic and phenotypic traits in livestock
- Peroxisome Proliferator-Activated Receptors
- Genetic Mapping and Diversity in Plants and Animals
- RNA Research and Splicing
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
- Genomics and Chromatin Dynamics
- RNA modifications and cancer
- Biochemical Analysis and Sensing Techniques
- Chromosomal and Genetic Variations
- Soybean genetics and cultivation
- Regulation of Appetite and Obesity
- Genetic diversity and population structure
- Soil and Water Nutrient Dynamics
- Plant nutrient uptake and metabolism
- Metabolomics and Mass Spectrometry Studies
- Soil Carbon and Nitrogen Dynamics
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Livestock and Poultry Management
- Potato Plant Research
- Adipose Tissue and Metabolism
- Cholesterol and Lipid Metabolism
- Wastewater Treatment and Nitrogen Removal
- Genomics and Phylogenetic Studies
University of Hong Kong
2023-2025
Henan Institute of Science and Technology
2025
Henan Agricultural University
2014-2024
Huazhong Agricultural University
2024
Ministry of Agriculture and Rural Affairs
2024
Xuzhou Medical College
2024
South China Agricultural University
2023
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2023
Shanghai Jiao Tong University
2022
Hainan University
2022
Liver is an important metabolic organ that plays a critical role in lipid synthesis, degradation, and transport; however, the molecular regulatory mechanisms of metabolism remain unclear chicken. In this study, RNA-Seq technology was used to investigate differences expression profiles hepatic metabolism-related genes associated pathways between juvenile laying hens. The study aimed broaden understanding liver chicken, thereby help improve performance poultry industry. analysis carried out on...
Egg-laying performance is of great economic importance in poultry, but the underlying genetic mechanisms are still elusive. In this work, we conduct a multi-omics and multi-tissue integrative study hens with distinct egg production, to detect hub candidate genes construct molecular networks contributing egg-laying phenotypic differences. We identifiy three as facilitators: TFPI2, which promotes GnRH secretion hypothalamic neuron cells; CAMK2D, FSHβ LHβ pituitary OSTN, granulosa cell...
There are five indigenous chicken breeds in Henan Province, China. These have their own unique phenotypic characteristics terms of morphology, behavior, skin and feather color, productive performance, but genetic basis is not well understood. Therefore, we analyzed the structure, genomic diversity, migration history populations selection signals genes responsible for gamecock phenotypes using whole genome resequencing. The results indicate that native chickens clustered most closely with...
Background Food waste remains a major problem for the world and food security. Despite fact that consumers are significant producers of waste, little research attention has been paid to college students. The present study aimed assess influence factors among Additionally, goal was improve students’ attitudes behaviors through labor education. Methods Through an online questionnaire survey, 407 students from three universities were asked about waste; 27 them randomly selected as object,...
The flat-headed loach (Oreonectes platycephalus) is a small fish inhabiting headwaters of hillstreams southern China. Its local populations are characterized by low genetic diversity and exceptionally high differentiation, making it an ideal model for studying population isolates' persistence adaptive potential. However, the lack Oreonectes reference genomes limits endeavours toward these ambitions. We assembled first haplotype-resolved chromosome-level genome genus using PacBio HiFi Hi-C...
Potential genetic variants associated with chicken egg production traits have been extensively identified, most of which are located in the non-coding regions genome. However, functional really drive egg-laying phenotype change remain elusive. In present study, by integrating previously screened related candidate variants, transcriptome data derived from 16 high- and low-yield Gushi chickens, epigenomic analyses, 22 potential (PFVs) were systematically identified. These PFVs potentially...
The detection and functional characterization of genomic structural variations are important for understanding the landscape genetic variation in chicken. A recently recognized aspect variation, called copy number (CNV), is gaining interest chicken studies. aim present study was to investigate pattern CNVs five characteristic breeds, which will be future studies associating phenotype with genome architecture. Using a commercial 385 K array-based comparative hybridization (aCGH) array, we...
Elongases of very long chain fatty acids (ELOVLs), a family first rate-limiting enzymes in the synthesis long-chain acids, play an essential role biosynthesis complex lipids. Disrupting any ELOVLs affects normal growth and development mammals. Genetic variations are associated with backfat or intramuscular acid composition livestock. However, effects ELOVL gene on breeding selection lipid deposition different tissues still unknown chickens.Genetic variation patterns genetic associations...
Breast muscle growth rate and intramuscular fat (IMF) content show apparent differences between fast-growing broilers slow-growing indigenous chickens. However, the underlying genetic basis of these phenotypic characteristics remains elusive. In this study, we investigate dynamic alterations three-dimensional genome architecture chromatin accessibility in breast across four key developmental stages from embryo to starter chick Arbor Acres (AA) Yufen (YF) The limited breed-specifically...
Abstract Background Estrogen plays an essential role in female development and reproductive function. In chickens, estrogen is critical for lipid metabolism the liver. The regulatory molecular network of chicken liver poorly understood. To identify estrogen-responsive genes functional sites on a genome-wide scale, we determined expression profiles mRNAs, lncRNAs, miRNAs estrogen-treated ((17β-estradiol)) control livers using RNA-Sequencing (RNA-Seq) studied receptor α binding by...
Egg-laying performance is one of the most important economic traits in poultry industry. Commercial layers can lay egg almost every day during their peak-laying period. However, many Chinese indigenous chicken breeds show a relatively low egg-laying rate, even To understand what makes difference production, we compared hypothalamus transcriptome profiles Lushi blue-shelled-egg chickens (LBS), breed with rate and Rhode Island Red (RIR), commercial layer high using RNA-seq. A total 753...
Skeletal muscle development and intramuscular fat (IMF) content, which positively contribute to meat production quality, are regulated by precisely orchestrated processes. However, changes in three-dimensional chromatin structure interaction, a newly emerged mediator of gene expression, during the skeletal IMF deposition have remained unclear. In present study, we analyzed differences content between one-day-old commercial Arbor Acres broiler (AA) Chinese indigenous Lushi blue-shelled-egg...
Few studies have been conducted regarding the biological function and regulation role of gga-miR-221-5p in liver. We compared conservation miR-221-5p among species investigated expression pattern gga-miR-221-5p, validating direct target genes by dual luciferase reporter assay, liver was studied overexpression inhibition. Furthermore, we explored its treatment with estrogen antagonists vivo vitro. The results showed that highly conserved species, expressed all tested tissues significantly...
Long noncoding RNAs (lncRNAs) have emergingly been implicated in mammalian lipid metabolism. However, their biological functions and regulatory mechanisms underlying adipogenesis remain largely elusive chicken. Here, we systematically characterized the genome-wide full-length lncRNAs livers of pre- peak-laying hens, identified a novel intergenic lncRNA, lncHLEF, an RNA macromolecule with calculated molecular weight 433 kDa. lncHLEF was primarily distributed cytoplasm chicken hepatocyte...
Indigenous chicken products are increasingly favored by consumers due to their unique meat and egg quality. However, the relatively poor egg-laying performance largely impacts economic benefits hinders sustainable development of local industry. Thus, excavating key genes effective molecular markers associated with is necessary improve production via genetic selection in indigenous breeds. In present study, comparative hypothalamic transcriptome between pre-laying (15 weeks old) peak-laying...
Cold tolerance at the seed germination stage is a critical trait for tobacco production. However, mechanism of under cold stress largely unknown in tobacco. In this study, we revealed that isopropylmalate synthase gene <italic>NtIPMS</italic> negatively regulates stress. Compared with wild-type (WT) tobacco, and seedling establishment were significantly reduced overexpression lines Physiological assays showed by influencing levels amino acids reactive oxygen species (ROS) The lower...
Modern breeding strategies have resulted in significant differences muscle mass between indigenous chicken and specialized broiler. However, the molecular regulatory mechanisms that underlie these remain elusive. The aim of this study was to identify key genes underlying breast development broiler.Two time-series RNA-sequencing profiles muscles were generated from commercial Arbor Acres (AA) broiler (fast-growing) Chinese Lushi blue-shelled-egg (LS) (slow-growing) at embryonic days 10, 14,...
Ammonia (NH3) emissions should be mitigated to improve environmental quality. Croplands are one of the largest NH3 sources, they must managed properly reduce their while achieving target yields. Herein, we report emissions, crop yield and changes in soil fertility a long-term trial with various fertilization regimes, explore whether can significantly reduced using 4R nutrient stewardship (4Rs), its interaction organic amendments (i.e., manure straw) wheat–maize rotation. Implementing 4Rs 6...
Apela, a novel endogenous peptide ligand for the G-protein-coupled apelin receptor, was first discovered and identified in human embryonic stem cells 2013. Apela has showed some biological functions promoting angiogenesis inducing vasodilatation of mammals by binding but little is known about its expression characteristics regulatory mechanism chicken. In present study, coding sequences chicken cloned. The evolution history potential function were analyzed. Subsequently, spatiotemporal...
Glycoprotein nonmetastatic melanoma protein B (GPNMB) is a vital secreted factor that promotes the occurrence of obesity in mammals. However, effects GPNMB on abdominal fat deposition still unknown chickens. In this study, we looked into genetic and expression association gene with traits chicken, found variation rs31126482 promoter was significantly associated weight (AFW, P < 0.05) percentage (AFP, 0.01). Express profile analysis indicated mainly expressed tissue, its level strongly...