A5038174945- Photosynthetic Processes and Mechanisms
- Biocrusts and Microbial Ecology
- Protist diversity and phylogeny
- Microbial Community Ecology and Physiology
- Algal biology and biofuel production
- Heat shock proteins research
- DNA Repair Mechanisms
- Metabolomics and Mass Spectrometry Studies
- Plant Stress Responses and Tolerance
- Aquatic Ecosystems and Phytoplankton Dynamics
- Advanced Proteomics Techniques and Applications
- Plant biochemistry and biosynthesis
- Legume Nitrogen Fixing Symbiosis
- Genetics, Aging, and Longevity in Model Organisms
- thermodynamics and calorimetric analyses
- Bacterial Genetics and Biotechnology
- Microbial Fuel Cells and Bioremediation
- Chromium effects and bioremediation
- Amino Acid Enzymes and Metabolism
- Geochemistry and Elemental Analysis
- Enzyme Structure and Function
- Paraquat toxicity studies and treatments
- Hemoglobin structure and function
- Bacterial biofilms and quorum sensing
- Genomics and Phylogenetic Studies
Bhabha Atomic Research Centre
2014-2024
Homi Bhabha National Institute
2015-2024
A proteomic approach was employed to elucidate the response of an agriculturally important microbe, Anabaena sp. strain PCC7120, methyl viologen (MV). Exposure 2 μM MV caused 50% lethality (LD50 ) within 6 h and modified cellular levels several proteins. About 31 proteins increased in abundance 24 decreased abundance, while 55 showed only a minor change abundance. Of these, 103 were identified by MS. Levels involved ROS detoxification chaperoning activities enhanced but that crucial light...
Heat stress caused rapid and severe inhibition of photosynthesis nitrate reduction in nitrate-supplemented cultures the cyanobacterium Anabaena sp. strain L-31, compared to nitrogen-fixing cultures. strains harbour two hsp60 family genes, groEL cpn60, respectively encoding 59 kDa GroEL 61 Cpn60 chaperonin proteins. Of these Hsp60 chaperonins, was strongly induced during heat stress, irrespective nitrogen status cultures, but rapidly repressed degraded heat-stressed or ammonium-supplemented...
Vascular endothelial growth factor (VEGF) is considered as one of the vital factors for angiogenesis, which primarily responsible progress and maintenance new vascular network in tumor. Numerous studies report that inhibition VEGF-induced angiogenesis a potent technique cancer suppression. Recently, RNA interference, especially small interfering (siRNA) signified promising approach to suppress gene expression. However, clinical implementation biological macromolecules such siRNA...
Anabaena sp. PCC 7120 possesses three genes coding for single‐stranded DNA ‐binding ( SSB ) protein, of which ssb1 was a single gene, and ssb2 ssb3 are the first their corresponding operons. Regulation truncated ssb genes, alr0088 alr7559 ), unaffected by N‐status growth. They were negatively regulated SOS ‐response regulatory protein LexA, as indicated (i) binding LexA to box regions , (ii) decreased expression downstream gfp reporter gene in Escherichia coli upon co‐expression LexA....
Single-stranded DNA binding (SSB) proteins are essential for all DNA-dependent cellular processes. Typical SSB have an N-terminal Oligonucleotide-Binding (OB) fold, a Proline/Glycine rich region, followed by C-terminal acidic tail. In the genome of heterocystous nitrogen-fixing cyanobacterium, Anabaena sp. strain PCC7120, alr0088 and alr7579 annotated as coding SSB, but truncated only OB-fold. silico analysis whole PCC7120 revealed presence another ORF 'all4779', hypothetical protein, having...