A5061070465- Microbial infections and disease research
- Animal Virus Infections Studies
- SARS-CoV-2 and COVID-19 Research
- Diphtheria, Corynebacterium, and Tetanus
- Veterinary medicine and infectious diseases
- COVID-19 Clinical Research Studies
- Bacteriophages and microbial interactions
- Clostridium difficile and Clostridium perfringens research
- Syphilis Diagnosis and Treatment
- Aquaculture disease management and microbiota
- Reproductive tract infections research
- Mycobacterium research and diagnosis
- SARS-CoV-2 detection and testing
- Pneumonia and Respiratory Infections
- COVID-19 Impact on Reproduction
- Biomarkers in Disease Mechanisms
- Leprosy Research and Treatment
- Mosquito-borne diseases and control
- Cytomegalovirus and herpesvirus research
- Indigenous Health and Education
- Virology and Viral Diseases
- Sex work and related issues
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Bacterial Identification and Susceptibility Testing
Universidade Federal da Bahia
2019-2024
Universidade Federal da Grande Dourados
2016-2022
Hospital Ana Nery
2022
Instituto de Saúde
2020
Ghent University
2012-2014
Universidade Federal de Pelotas
2009-2014
Universidade Federal de Santa Maria
2006
Caseous lymphadenitis (CLA) is a chronic disease that affects small ruminants and causes economic losses in the associated breeding system. The causative agent of CLA Corynebacterium pseudotuberculosis , Gram-positive bacterium exhibits tropism for external internal lymph nodes induces abscess formation host. Bacterial communities often produce biofilm matrix serves various functions, including protection against hostile environmental conditions, antibiotics, host immune response. Although...
Objective: To evaluate the hematological and lymphocyte profiles of individuals with COVID-19, as well to identify ancestral profile through Ancestry Informative Markers from two cities in Northeast region Brazil. Methods: Data 58 COVID-19 who presented mild (39) severe (19) clinical conditions were analyzed. The was identified by immunophenotyping genotyping via PCR qPCR analysis. analyzed descriptive statistics using IBM SPSS Statistics software. study approved Research Ethics Committee...
Mycoplasma hyopneumoniae is the causative agent of enzootic pneumonia and responsible for significant economic losses to pig industry. To better understand mode action a commercial, adjuvanted, inactivated whole cell vaccine influence diversity on efficacy vaccination, we investigated samples from vaccinated non-vaccinated pigs experimentally infected with either low (LV) or highly virulent (HV) M. strain. Non-vaccinated sham-infected control groups were included. Lung tissue collected at 4...
Porcine enzootic pneumonia (PEP), which is caused by the fastidious bacterium Mycoplasma hyopneumoniae, one of most economically important diseases in pig industry worldwide. Commercial bacterins provide only partial protection; therefore, development more efficient vaccines against PEP necessary. In this study, cellular and humoral immune responses elicited DNA recombinant subunit based on P37, P42, P46 P95 antigens M. hyopneumoniae were evaluated after intramuscular inoculation BALB/c...
A colibacilose é a enfermidade entérica de maior impacto na suinocultura, sendo ocasionada por cepas enterotoxigênicas Escherichia coli. Quarenta isolados clínicos suínos com diarréia e 13 ambientais foram analisados quanto ao perfil genotípico, relação genética resistência antimicrobiana. O gene que codifica para toxina Stb foi identificado em 50% dos clínicos, seguido Sta Lt, 35%. Dentre os fatores adesinas pesquisados, F18 encontrada 27,5% das amostras. técnica ERIC-PCR utilizada...
Mycoplasma hyopneumoniae, the etiological agent of swine enzootic pneumonia, is an important pathogen in industry worldwide. Vaccination most cost-effective strategy for controlling and prevention this disease. However, investigations on pathogenicity mechanisms as well current serological detection methods development new recombinant subunit vaccines are hampered by lack known characterized species-specific M. hyopneumoniae antigens. In work, 54 predicted genes encoding proteins with...
Mycoplasma hyopneumoniae is the causative agent of porcine enzootic pneumonia and results in significant economic losses swine production worldwide. Vaccination considered to be most cost-effective strategy for control prevention this disease. However, development new recombinant subunit vaccines often hampered by unusual codon usage bacterium. To express M. proteins heterologous systems such as Escherichia coli, TGA codons that encode tryptophan genes need replaced with TGG codon. In study...
The present field study investigated the efficacy of early Mycoplasma hyopneumoniae vaccination in a farrow-to-finish pig herd with respiratory disease late fattening period due to combined infections M and viral pathogens. Five hundred forty piglets were randomly divided into three groups 180 each: two vaccinated (Stellamune Once) at either 7 (V1) or 21 days age (V2), third group was left non-vaccinated (NV). treatment housed different pens within same compartment during nursery period, but...
Mycoplasma hyopneumoniae is the etiological agent of porcine enzootic pneumonia (EP), which a respiratory disease responsible for huge economic losses in pig industry worldwide. The commercially available vaccines provide only partial protection and are expensive. Thus, development alternatives prophylaxis EP critical improving health. use multiple antigens same immunization may represent promising alternative. In present study, seven secreted proteins M. were cloned, expressed Escherichia...
Enzootic Pneumonia (EP) caused by Mycoplasma hyopneumoniae results in major economic losses to the swine industry. Hence, identification of factors that provide protection against EP could help develop effective vaccines. One such factor provides partial are bacterins. Therefore, aim this study was verify induction antibodies fifteen M. antigens, strongly recognized immune system during natural infection, mice vaccinated with six commercial Each group inoculated one bacterin, and...
There is a scarcity of studies on the prevalence Trichomonas vaginalis (TV) in indigenous populations Brazil. We conducted cross-sectional study between January and December 2018, women living nearby an urban center Midwest region Brazil determined TV. Factors associated with TV infection comparison molecular direct microscopy diagnoses were determined. 241 aged above 18 years participated study. Cervical vaginal brush samples collected to diagnose through polymerase chain reaction (PCR)....
Although the adaptive immune responses to CoronaVac vaccine are known, their dynamics in indigenous communities remain unclear. In this study, we assessed humoral and cellular (Sinovac Biotech Life Sciences, 2021 NCT05225285, Beijing, China), immunized Brazilian individuals.
Current prevention methods for the transmission of Mycobacterium leprae, causative agent leprosy, are inadequate as suggested by rate new leprosy cases reported. Simple large-scale detection M. leprae infection crucial early and disease control. The present study investigates production seroreactivity a recombinant polypeptide composed various protein epitopes. structural physicochemical parameters this construction were assessed using in silico tools. Parameters like subcellular...
This study assessed the seroprevalence of SARS-CoV-2 in 496 asymptomatic individuals from Mato Grosso do Sul, located Dourados, largest periurban indigenous area Brazil, January 25 to February 4, 2021. The volunteers participated before receiving their first dose CoronaVac inactivated vaccine. For screening, blood samples were collected and analyzed using rapid tests enzyme-linked immunosorbent assay (ELISA). We observed varying trends total anti-SARS-CoV-2 antibodies across different...
This cross-sectional observational study that describes the epidemiological data of first year COVID-19 pandemic in Mato Grosso do Sul State, aimed to demonstrate differences between indigenous and non-indigenous populations, characterize confirmed cases according risk factors related ethnicity, comorbidities their evolution verify challenges facing disease Brazil. SIVEP-Gripe E-SUS-VE, a nationwide surveillance database Brazil, from March 2020 2021 state, were used compare survivors...