Ana Raquel Pengelly

ORCID: 0000-0003-4289-3815
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Genetics, Aging, and Longevity in Model Organisms
  • Infant Development and Preterm Care
  • Neurobiology and Insect Physiology Research
  • Circadian rhythm and melatonin
  • Lipid metabolism and biosynthesis
  • Metabolomics and Mass Spectrometry Studies
  • Child Nutrition and Feeding Issues
  • Early Childhood Education and Development

The Francis Crick Institute
2017

Early-life nourishment exerts long-term influences upon adult physiology and disease risk. These lasting effects of diet are well established but the underlying mechanisms only partially understood. Here we show that restricting dietary yeast during Drosophila development can, depending subsequent environment, more than double median lifespan. Developmental acts via a influence production toxic molecules, which term autotoxins, shed into environment shorten lifespan both sexes. Autotoxins...

10.1038/s41467-017-01740-9 article EN cc-by Nature Communications 2017-11-03
Coming Soon ...