A5032578391- Pituitary Gland Disorders and Treatments
- Diabetes Treatment and Management
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Diabetes Management and Research
- Thyroid Disorders and Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Growth Hormone and Insulin-like Growth Factors
- Health Literacy and Information Accessibility
- Meningioma and schwannoma management
- Adrenal and Paraganglionic Tumors
- Sexual Differentiation and Disorders
- Glioma Diagnosis and Treatment
- Vitamin D Research Studies
- Metabolism and Genetic Disorders
- Regulation of Appetite and Obesity
- Diabetes Management and Education
- Adipose Tissue and Metabolism
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Disease and Adiposity
- Chronic Disease Management Strategies
- Sympathectomy and Hyperhidrosis Treatments
- Natural Antidiabetic Agents Studies
- Nuclear Structure and Function
- Adrenal Hormones and Disorders
King Fahd Medical City
2017-2024
King Faisal Specialist Hospital & Research Centre
2024
University of British Columbia
2024
Alfaisal University
2024
King Fahad Specialist Hospital
2024
Saudi Heart Association
2024
Shaikh Khalifa Medical City
2020
Maternity and Children's Hospital
2020
University Medical Center Groningen
2020
University of Groningen
2020
OBJECTIVE Type 2 diabetes is associated with insulin resistance and skeletal muscle mitochondrial dysfunction. We have found that subjects early-onset type show incapacity to increase Vo2max in response chronic exercise. This suggests a defect Here, we explored the nature of mechanisms involved. RESEARCH DESIGN AND METHODS Muscle biopsies were collected from young diabetic obese control before after acute or exercise protocols, expression genes and/or proteins relevant function was measured....
This study determined the prevalence and risk factors for diabetic peripheral neuropathy (DPN), painful DPN foot ulceration (DFU) in patients with type 2 diabetes secondary healthcare Qatar, Kuwait Kingdom of Saudi Arabia. Adults aged 18-85 years were randomly enrolled from healthcare, underwent clinical metabolic assessment. was evaluated using vibration perception threshold neuropathic symptoms Diabetic Peripheral Neuropathy Douleur Neuropathique 4 questionnaire. A total 3,021 individuals...
Construction workers (CW) are at increased risk for a range of chronic diseases. We screened 983 CW diabetes and cardiometabolic risk. The age was 18–64 years, with mean 36.3 years. Self-reported questionnaires, Finnish score fasting blood tests were collected the workplace. unadjusted prevalence pre-diabetes type 2 mellitus 3.6% 1.2%, respectively; 21% had metabolic syndrome (MetS). majority either overweight (48.3%) or obese (21.8%). In regression model, remained strongest predictor...
Abstract Background Congenital generalized lipodystrophy (CGL) is a rare inherited disease characterized by near-total absence of adipose tissue and associated with organ system abnormalities severe metabolic complications. Here, we have analyzed the characteristics largest CGL cohort from Middle East North Africa (MENA) who not received lipodystrophy-specific treatment. Methods was diagnosed clinically treating physicians through physical assessment supported genetic analysis, fat loss...
Objectives: This study aimed to assess the correlation between glycated hemoglobin A1 (HbA1c), time in range (TIR), and glycemic management indicator (GMI) patients with both type 1 diabetes (T1D) 2 (T2D) who were using a flash glucose monitoring (FGM) device (FreeStyle Libre; Abbott Diabetic Care, Witney, UK). Methods: was retrospective that looked at T1D T2D FreeStyle Libre users' LibreView database period January 2020 June 2022. The conducted department King Fahad Medical City (KFMC)...
We have previously reported that immigrants in Ireland poorer glycemic control compared with a matched population of Irish patients. This may be associated poor diabetes self-care and low health literacy.To compare the profile non-Irish-national patients i.e. immigrant (IM) (IR) attending hospital clinic to evaluate differences literacy between two cohorts.We studied self-management 52 randomly selected type 2 48 Irish/Caucasian Rapid Estimate Adult Literacy Medicine (REALM) was used assess...
<h3>Objectives:</h3> To identify the prevalence of health literacy among adult Saudi with type 2 diabetes mellitus (T2DM) patients and determine clinical factors that are associated scores including glycemic control. <h3>Method:</h3> A cross-sectional study included 249 T2DM (99 males 150 females) who visited Diabetes Clinic Endocrine Center at King Fahad Medical City, Riyadh, Arabia between September 2017 January 2018. The short test Functional Health Literacy in Adults (Arabic version) was...
Thyroid function tests (TFTs) changes in obese people have been studied with increasing interest, however, studies inconsistent hence it remains poorly understood. We compared the TFTs of morbidly euthyroid Saudi subjects non-obese controls and then we examined influence leptin, adiponectin, insulin resistance on TFTs.Fifty-five attending bariatric surgery clinic 52 age-and gender-matched were recruited. measured body weight, BMI, composition, thyroid-stimulating hormone (TSH), Free T4...
Abstract Background Plurihormonal pituitary adenomas are a unique type of that secrete two or more hormones normally associated with separate cell types have different immunocytochemical and ultrastructural features. Although they represent 10–15% all tumors, only small fraction plurihormonal clinically multiple hormones. The most common hormone combinations secreted by growth hormone, prolactin, one glycoprotein hormonal symptom is acromegaly (50%). aim this case report to bring awareness...
Introduction & Objective: Diabetes is a major public health problem, in 2021, affect 537 million adults, and it estimated to 643 adults by 2030, associated with 6.7 adult deaths 2021(1). The Usefulness of Many non-insulin therapies has been investigated type-1 diabetes like Metformin, Sodium-Glucose co-transporter-2 inhibitors. Recent evidence on Semaglutide early Type-1 shows promising effect. study aimed determine whether Glucagon-Like Peptide-1 Receptor agonist (GLP-1) added Insulin...
Abstract Background Adjunctive treatment with sodium-glucose co-transporters 2 inhibitors (SGLT2- I) has been successfully used in patients type 1 diabetes mellitus (T1DM) recent years to improve glycemic control and reduce body weight without increasing the risk of hypoglycemia; however, there is a scarcity evidence for real-world experience their use T1DM Saudi patients. The purpose this study was evaluate efficacy safety empagliflozin as off-label adjunctive therapy T1DM. Methods This...
Type 1 diabetes mellitus (T1DM) is characterized by autoimmune destruction of insulin-producing pancreatic beta (β-) cells. Previous studies suggested an imbalance between and pro- anti-inflammatory cytokines exacerbates T1DM development.We aimed to test the hypothesis that patients with carry a higher frequency regulatory genes associated low levels interleukin-4 (IL-4), its receptor (IL-4R), interleukin-10 (IL-10).Accordingly, we compared frequencies five different single nucleotide...
Resistance to thyroid hormone-beta (RTHbeta) is a rare inherited syndrome characterized by variable reduced tissue responsiveness the intracellular action of triiodothyronine (T3), active form hormone. The presentation RTHbeta quite and mutations in hormone receptor beta (THR-B) gene have been detected up 90% patients. proband was 34-year-old Jordanian male who presented with intermittent palpitations. His function tests (TFTs) showed discordant profile high free T4 (FT4) at 45.7 pmol/L...
Abstract Type 1 diabetes (T1D) is an autoimmune disease characterized by progressive destruction of insulin‐producing pancreatic beta cells. This multifactorial has a strong genetic component associated with the human leukocyte antigens (HLA) and non‐HLA regions. In this study, we compared frequencies HLA‐DRB1 alleles single‐nucleotide polymorphisms (SNPs) genes coding for: toll‐like receptors (TLRs), tumour necrosis factor (TNF), interleukin‐1 (IL‐1), receptor type (IL‐1R1), antagonist...
Congenital adrenal hyperplasia (CAH) consists of variable disorders sex determination and differentiation. 17α-hydroxylase deficiency (17OHD) is an uncommon form those disorders, which typically characterized by hypertension, hypokalemia, failure puberty, ambiguous genitalia. The enzyme encoded the CYP17A1 gene it required for synthesis cortisol steroids. affected females with 17OHD usually present primary amenorrhea delayed are associated hypertension hypokalemia while male patients might...
Introduction & Objectives: Diabetic retinopathy(DR) is associated with significant visual impairment and quality of life in people living diabetes, however, studies on the prevalence risk factors from Saudi Arabia have been inconsistent, hence aim this was to define prevalence, predictors DR a large sample subjects type 1 diabetes (T1DM) T2DM. Methods: This cross-sectional study that included both T2DM T1DM (if duration &gt; 5 years) who attended clinics at King Fahad Medical City...