Chengxiang Yang

ORCID: 0000-0003-4297-5810
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About
Contact & Profiles
Research Areas
  • Rock Mechanics and Modeling
  • Landslides and related hazards
  • Anesthesia and Sedative Agents
  • Pain Mechanisms and Treatments
  • Anesthesia and Neurotoxicity Research
  • Anesthesia and Pain Management
  • Cancer, Stress, Anesthesia, and Immune Response
  • Geotechnical and Geomechanical Engineering
  • Geotechnical Engineering and Analysis
  • Tunneling and Rock Mechanics
  • Healthcare and Venom Research
  • Botulinum Toxin and Related Neurological Disorders
  • Nausea and vomiting management
  • Geomechanics and Mining Engineering
  • Ion channel regulation and function
  • Grouting, Rheology, and Soil Mechanics
  • Cancer Treatment and Pharmacology
  • Airway Management and Intubation Techniques
  • Geophysical Methods and Applications
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Blood transfusion and management
  • Soil and Unsaturated Flow
  • Nerve injury and regeneration
  • Cardiac Ischemia and Reperfusion
  • Plant-based Medicinal Research

Northeastern University
2010-2024

National Taipei University of Technology
2024

Dalian University of Technology
2023

First People's Hospital of Foshan
2010-2020

Institute of Rock and Soil Mechanics
2020

Sichuan Agricultural University
2016

North China University of Technology
2014

Foshan Hospital of TCM
2008-2013

CPC Heilongjiang Provincial Committee Party School
2011

Curtin University
2010

To analyze and predict the mechanical behaviors of deep hard rocks, some key issues concerning rock fracturing mechanics for excavations are discussed. First, a series apparatuses methods have been developed to test properties rocks under high true triaxial stress paths. Evolution mechanisms stress-induced disasters in excavations, such as spalling, cracking, massive roof collapse, large deformation rockbursts, recognized. The analytical theory process masses, including three-dimensional...

10.1016/j.jrmge.2021.12.003 article EN cc-by-nc-nd Journal of Rock Mechanics and Geotechnical Engineering 2021-12-23

Neuropathic pain (NP) is caused by damage to the nervous system, resulting in aberrant pain, which associated with gene expression changes sensory pathway. However, molecular mechanisms are not fully understood. A non-coding Ribose Nucleic Acid (ncRNA) an RNA molecule that translated into a protein. NcRNAs involved many cellular processes, and mutations or imbalances of repertoire within body can cause variety diseases. Although ncRNAs have recently been shown play role NP pathogenesis,...

10.3389/fnmol.2017.00091 article EN cc-by Frontiers in Molecular Neuroscience 2017-04-03

This study aimed to elucidate the role of T-type calcium channels in nociceptive signal transmission at spinal level. The chronic compression dorsal root ganglion (CCD) rat model was adopted. Three doses (50, 100 and 200 microg groups Mib50, Mib100 Mib200, respectively) specific Ca2+ channel inhibitors mibefradil (Mib) or normal saline (NS) were intrathecally administered on 5th day after CCD had been established. paw withdrawal latency from a noxious thermal stimulus mechanical threshold...

10.1159/000276981 article EN Pharmacology 2010-01-01

TRESK gene recombinant adenovirus (109 IU/ml), which has been constructed successfully in our previous study, was implemented through an intrathecal injection. The fact that the method can effectively upregulate expression of mRNA dorsal root ganglia spared nerve injury rats verified. We also investigated role attenuating tactile allodynia and thermal hyperalgesia rats. Spared to sciatic induced persistent allodynia, but had no effect on hyperalgesia. Intrathecal injection (25 µl) into...

10.1097/wnr.0b013e32835d8431 article EN Neuroreport 2013-01-22

Based on genetic algorithm and programming, a new evolutionary is developed to evolve mathematical models for predicting the behavior of complex systems. The input variables are property parameters systems, which include geometry, deformation, strength parameters, etc. On other hand, output system responses, such as displacement, stress, factor safety, To improve efficiency evolution process, two-stepped approach adopted; two steps structure parameter optimization steps. In step, family...

10.1061/(asce)0887-3801(2004)18:2(145) article EN Journal of Computing in Civil Engineering 2004-03-16
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