A5032298491- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Interpreting and Communication in Healthcare
- Dementia and Cognitive Impairment Research
- Medical Imaging and Analysis
- Cardiovascular Health and Risk Factors
- Trauma and Emergency Care Studies
- Optical Imaging and Spectroscopy Techniques
- Wireless Body Area Networks
- Pharmacological Effects and Toxicity Studies
- Health, Environment, Cognitive Aging
- Traffic and Road Safety
- Indigenous Health, Education, and Rights
- Neonatal and fetal brain pathology
- Photoacoustic and Ultrasonic Imaging
- Cervical Cancer and HPV Research
- Diet and metabolism studies
- Dental Health and Care Utilization
- Aging, Elder Care, and Social Issues
- Health and Lifestyle Studies
- Epilepsy research and treatment
- Neurobiology of Language and Bilingualism
South Western Sydney Local Health District
2022-2025
UNSW Sydney
2022-2025
The Royal Melbourne Hospital
2019-2024
University of Otago
2024
The University of Melbourne
2019-2024
Camden and Campbelltown Hospitals
2024
Monash University
2022-2024
Alfred Health
2021-2024
The University of Western Australia
2024
Instituto Nacional do Câncer
2023
<h3>Importance</h3> Intravenous thrombolysis with tenecteplase improves reperfusion prior to endovascular thrombectomy for ischemic stroke compared alteplase. <h3>Objective</h3> To determine whether 0.40 mg/kg of safely before vs 0.25 in patients large vessel occlusion stroke. <h3>Design, Setting, and Participants</h3> Randomized clinical trial at 27 hospitals Australia 1 New Zealand using open-label treatment blinded assessment radiological outcomes. Patients were enrolled from December...
Background: Indigenous Peoples have been reported to experience higher rates of stroke, poorer access high-quality acute and rehabilitation stroke services, worse post- outcomes compared dominant cultures residing in the same countries. The aim this statement is summarise available evidence on barriers contributing these inequities, effective solutions that deployed tested, present key recommendations advance field. Methods: We conducted a scoping review searching Medline, Embase, CINHAL,...
Rural, remote, and Indigenous stroke patients have worse outcomes than urban Australians. This may be due to lack of timely access expert facilities.We aimed describe the characteristics who underwent aeromedical retrieval for stroke, estimate transfer times, investigate if flight paths corresponded with locations units (SUs) throughout Australia.Prospective review routinely collected Royal Flying Doctor Service (RFDS) data. Patients an RFDS July 2014-June 2018 (ICD-10 codes: I60-I69), were...
Abstract Background Lack of awareness cognitive decline (ACD) is common in late-stage Alzheimer’s disease (AD). Recent studies showed that ACD can also be reduced the early stages. Methods We described different trends evolution over 3 years a cohort memory-complainers and their association to amyloid burden brain metabolism. studied impact at baseline on scores’ between longitudinal changes score. Results 76.8% subjects constantly had an accurate (reference class). 18.95% steadily...
Cardiovascular disease contributes significantly to burden among many Indigenous populations. However, data on stroke incidence in populations are sparse. We aimed investigate what is known of countries with a very high Human Development Index (HDI), locating the research broader context health.
Rationale: The benefit of tenecteplase in the treatment large vessel occlusion (LVO) patients presenting within 24 hours symptom onset remains unclear. Aim: To assess effectiveness and safety tenecteplase, compared to standard care, first with a LVO target mismatch on perfusion CT. Methods Design: “Extending time window for Tenecteplase by Effective Reperfusion peNumbrAL tissue Large Vessel Occlusion” (ETERNAL-LVO) trial is prospective, randomized, open-label, blinded endpoint, phase 3,...
Stroke is the second most common cause of death and remains a persistent health challenge globally. Due to its highly time-sensitive nature, earlier stroke treatments should be enforced for improved patient outcome. The mobile unit (MSU) was conceptualized implemented deliver diagnosis treatment in ultra-early time window (<1 h) pre-hospital setting has shown clinically effective. However, due geographical challenges, rural communities are still unable receive timely intervention, as...
Mobile stroke units (MSUs) equipped with a CT scanner are increasingly being used to assess and treat patients' prehospital thrombolysis transfer them the most appropriate hospital for ongoing care thrombectomy when indicated. The effect of MSUs in both reducing time reperfusion treatment improving patient outcomes is now established. There an opportunity improve efficacy provided by MSU. Tenecteplase potent plasminogen activator, which may have benefits over standard lytic alteplase....
BACKGROUND: Most estimates of stroke incidence among Aboriginal and Torres Strait Islander (hereinafter Aboriginal) Australians are confined to single regions include small sample sizes. We aimed measure compare in non-Aboriginal residents across central western Australia. METHODS: Whole-population multijurisdictional person-linked data from hospital death datasets were used identify admissions stroke-related deaths (2001–2015) Western Australia, South the Northern Territory. Fatal...
Background Mobile stroke units have been shown to deliver faster patient care and improve clinical outcomes. However, costs associated with staffing limit their use densely populated cities. Using the Melbourne mobile unit, we aim evaluate safety, timeliness, resource efficiency of a telemedicine model, where neurologist assesses remotely, via telemedicine, compared an onboard model. We hypothesize that, without compromising model will provide timely superior efficiency. Methods prospective,...
Vessel Plus is an open acccess journal, which publishes articles related to vascular diseases, including acute respiratory distress syndrome, aneurysm, atherosclerosis, hypertension, stroke, peripheral or pulmonary etc.
Introduction In acute stroke, identifying early changes (parenchymal hypodensity) on non-contrast CT (NCCT) can be challenging. We aimed to identify whether the accuracy of clinicians in detecting hypodensity ischaemic stroke patients a is improved with use an Artificial Intelligence (AI) based, automated detection algorithm (HDT) using MRI-DWI as gold standard. Methods The study employed case-crossover within-clinician design, where 32 were tasked lesions NCCT scans for five priori selected...
Mortality from stroke remains high in Australia, especially for patients located outside the metropolitan cities. This is because they have limited access to specialized facilities optimal treatment. Mobile units capability take CT scanners out patient however current commercial scanner designs are large and heavy. As such, this paper aims design develop a lightweight use mobile unit (either road-based or air-based ambulance) bring healthcare solution rural remote areas. We used engineering...
Cardiovascular disease is the most common cause of death and disability in indigenous communities but limited prospective data exist about stroke.To estimate difference stroke recognition, risk factors, treatment rates outcomes between non-indigenous peoples admitted to Wagga Rural Referral Hospital (WWRRH) over a 5-year period with suspected acute stroke.All strokes presenting 33 peripheral hospitals within Murrumbidgee Local Health District (MLHD) were transferred WWRRH prospectively...
Background and AimQuantifying stroke incidence mortality is crucial for disease surveillance health system planning. Administrative data offer a cost-effective alternative to "gold standard" population-based studies. However, the optimal methodology establishing deaths from administrative remains unclear. We aimed determine method identifying stroke-related in datasets as fatal component of incidence, comparing counts derived using underlying all causes death (CoD).MethodUsing...
Aboriginal and Torres Strait Islander Indigenous Australians are not adequately screened or treated for cardiovascular disease,1Calabria B Korda RJ Lovett RW et al.Absolute disease risk lipid-lowering therapy among Australians.Med J Aust. 2018; 209: 35-41Crossref PubMed Scopus (35) Google Scholar, 2Peiris DP Patel AA Cass A al.Cardiovascular management peoples in primary health care settings: findings from the Kanyini Audit.Med 2009; 191: 304-309Crossref (61) Scholar less likely to receive...
Abstract Objective We performed a pilot stroke incidence study, focused on feasibility and inclusion of the CONSIDER reporting guidelines, to model design future population‐based study aiming definitively determine incidence, antecedents, treatment, outcomes. Study Prospective (pilot study). Setting, participants All people aged 15 years or older who lived in postcode‐defined areas South Australia Northern Territory (885 472 people, including 45 127 Aboriginal [5.1%]) diagnosed with for...