A5037006422- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Nanoparticle-Based Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Essential Oils and Antimicrobial Activity
- Electrohydrodynamics and Fluid Dynamics
- Insect Pest Control Strategies
- RNA Interference and Gene Delivery
- Surfactants and Colloidal Systems
- Graphene and Nanomaterials Applications
- Drug Solubulity and Delivery Systems
- Proteins in Food Systems
- Inhalation and Respiratory Drug Delivery
- Microfluidic and Capillary Electrophoresis Applications
- Nanoparticles: synthesis and applications
- Bee Products Chemical Analysis
- Healthcare and Venom Research
- Enzyme Catalysis and Immobilization
- Insect and Pesticide Research
- Nanocomposite Films for Food Packaging
- Wound Healing and Treatments
- Curcumin's Biomedical Applications
- Advanced Nanomaterials in Catalysis
- Bone Tissue Engineering Materials
- Conducting polymers and applications
North Khorasan University of Medical Sciences
2018-2025
Tehran University of Medical Sciences
2015-2024
University of North Sumatra
2023
Hamdard University
2022
Ilam University
2018
Biotechnology Research Center
2012-2014
Islamic Azad University, Ahvaz Branch
2013
Medical Technologies (Czechia)
2010-2011
University of Bradford
2008-2011
University of Groningen
2009
Abstract The current study aimed to enhance the efficacy of peripheral nerve regeneration using an electrically conductive biodegradable porous neural guidance conduit for transplantation allogeneic Schwann cells (SCs). was produced from polylactic acid (PLA), multiwalled carbon nanotubes (MWCNTs), and gelatin nanofibrils (GNFs) coated with recombinant human erythropoietin‐loaded chitosan nanoparticles (rhEpo‐CNPs). PLA/MWCNTs/GNFs/rhEpo‐CNPs had porosity 85.78 ± 0.70%, contact angle 77.65...
The present study has examined the effects of ZnO and TiO2 nanoparticles (40–70 nm range) in presence absence UVA light human sperm lymphocytes dark (D), after pre-irradiation with UV (PI) simultaneous irradiation (SI). For both nanoparticles, percentage reduction head DNA was greater for PI SI samples compared treated dark. However regard to photogenotoxicity, exhibited no significant differences when results were compared, except at lowest concentration case TiO2. lymphocytes, responses...
The structure and dynamics of a single molecule the nonionic surfactant polysorbate 80 (POE (20) sorbitan monooleate; Tween 80®) as well micelle comprising sixty molecules in water have been investigated by molecular simulation. In its free state samples almost entire conformational space. is compact exhibits prolate ellipsoid shape, with surface being dominated polar terminal groups POE chains. radius gyration was 26.2 Å. physical radius, determined from both atomic density, about 35...
A nanoemulsion drug delivery system was developed to increase the oral bioavailability of mebudipine as a calcium channel blocker with very low profile. The impact nano-formulation on pharmacokinetic parameters in rats investigated. Nanoemulsion formulations containing ethyl oleate, Tween 80, Span polyethylene glycol 400, ethanol and deionized water were prepared using probe sonicator. optimum formulation evaluated for physicochemical properties, such particle size, morphology stability....
In this paper, doping of europium (Eu) and gadolinium (Gd) as high-Z elements into zinc oxide (ZnO) nanoparticles (NPs) was designed to optimize restricted energy absorption from a conventional radiation therapy by X-ray. Gd/Eu-doped ZnO NPs with size 9 nm were synthesized chemical precipitation method. The cytotoxic effects Eu/Gd-doped determined using MTT assay in L929, HeLa, PC3 cell lines under dark conditions well exposure ultraviolet, X-ray, γ radiation. Doped at 20 μg/mL concentration...
Eugenol is the main constituent of clove oil with anti-inflammatory properties. In this work, for first time, O/W nanoemulsion eugenol was designed evaluation effects as a topical delivery system. Topical formulations containing 1%, 2% and 4% well system 0.5% piroxicam were prepared. Further to physicochemical examinations, such determination particle size, polydispersity index, zeta potential physical stability, activity examined in carrageenan-induced paw edema rats. The optimum...
Background: The aim of this study was to prepare curcumin nanoemulsion (CR-NE) solve the problems associated with poor water solubility and low bioavailability CR test its efficiency in treatment acute chronic toxoplasmosis mouse models. Materials methods: CR-NE 1% prepared using spontaneous emulsification by soybean as oil phase; a mixture Tween 80 85 surfactant; ethanol cosurfactant distilled water. Particle size zeta potential NE were assessed Nano-ZS90 dynamic light scattering. Stability...
Cyclosporine A (CsA) is known as a neuroprotective agent against cerebral ischemia/reperfusion (I/R) in animal models. However, the significant therapeutic effects of CsA have been observed high systemic doses or manipulating blood-brain barrier, resulting side and toxicity. As liposome nanocarriers developed for efficient delivery peptide proteins, liposomal (Lipo-CsA) could improve injuries. In this study, formulation (CsA at dose 2.5 mg/kg) was prepared to assess brain injury outcomes 90...
Silk fibroin/chitosan/ZnO/
Core/shell<sc>l</sc>-ascorbic acid/poly(vinyl alcohol)–chitosan (ASC/PVA–CS) nanofibers were successfully prepared utilizing coaxial electrospinning and their characteristics compared with monolithic blend PVA–CS–ASC nanofibers.
In this study, we investigated whether ZnO coating on Ag nanoparticles (NPs) tunes electron flux and hole figuration at the metal–semiconductor interface under UV radiation. This effect triggers photoactivity generation of reactive oxygen species from Ag@ZnO NPs, which results in enhanced cytotoxic effects apoptotic cell death human breast cancer cells (MDA-MB231). context, upregulation cascade proteins (i.e., Bax/Bcl2 association, p53, cytochrome c, caspase-3) along with activation...
Mesoporous silica nanoparticles (MSNs) have ideal characteristics as next generation of controlled drug delivery systems. In this study, a MSN-based nanocarrier was fabricated and gold nanoparticle (GNP)-biotin conjugates were successfully grafted onto the pore outlets prepared MSN. This bioconjugate served capping agent with peptide-cleavable linker sensitive to matrix metalloproteinases (MMPs), which are overexpressed extracellular proteolytic enzymes in cancerous tissue. The nanocarriers...