A5002538753- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Transplantation: Methods and Outcomes
- Multiple and Secondary Primary Cancers
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Palliative Care and End-of-Life Issues
- Asthma and respiratory diseases
- Global Cancer Incidence and Screening
- Radiomics and Machine Learning in Medical Imaging
- Inhalation and Respiratory Drug Delivery
- Economic and Financial Impacts of Cancer
- Health Systems, Economic Evaluations, Quality of Life
- Medical Imaging and Pathology Studies
- Renal Transplantation Outcomes and Treatments
- Ferroptosis and cancer prognosis
- Lung Cancer Research Studies
- Colorectal Cancer Treatments and Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cancer survivorship and care
- Tracheal and airway disorders
- Advances in Oncology and Radiotherapy
- COVID-19 and healthcare impacts
- Esophageal Cancer Research and Treatment
- Infection Control and Ventilation
Ludwig-Maximilians-Universität München
1997-2025
German Center for Lung Research
2018-2025
LMU Klinikum
2021-2025
Medical University of Graz
2025
München Klinik
2023
Areté Associates (United States)
2023
Immungenetics (Germany)
2022
Universität Ulm
2022
Helmholtz Zentrum München
2016-2020
Max Planck Institute for Molecular Genetics
2002
With the great advances in thoracic surgery, radical excision for pulmonary carcinoma has become a relatively safe and frequent operation, offering to patient new hope of cure.However, if results operative treatment are be accurately assessed, ordinary gross pathology must carefully fully recorded, it is little use comparing survival rates unless attention paid not only different histological types growth, but also anatomical factors such as location, size, site origin, which can seriously...
Abstract Treatment with single agent immune checkpoint inhibitors (ICIs) has tremendously changed second line therapy in NSCLC. However, there are still no reliable biomarkers predicting response and survival this group of patients. PD-L1 revealed to be a correlating, but perfect marker. Therefore, we sought investigate prospective study, whether inflammation status cytokine profile could serve as additional guiding treatment decision for ICIs 29 stage IV NSCLC patients receiving PD-1...
Evaluation of pulmonary function impairment after COVID-19 in persistently symptomatic and asymptomatic patients all disease severities characterisation risk factors.Patients with confirmed SARS-CoV-2 infection underwent prospective follow-up testing blood gas analysis during steady-state cycle exercise 4 months acute illness. Pulmonary (PFI) was defined as reduction below 80% predicted DLCOcSB, TLC, FVC, or FEV1. Clinical data were analyzed to identify factors for impaired function.76...
Molecular matching is a new approach for virtual histocompatibility testing in organ transplantation. The aim of our study was to analyze whether the risk de novo donor‐specific HLA antibodies (dnDSA) after lung transplantation (LTX) can be predicted by molecular algorithms (MMA) and their combination. In this retrospective we included 183 patients undergoing LTX at center from 2012–2020. We monitored dnDSA development 1 year. Eplet mismatches (epMM) using HLAMatchmaker were calculated...
Evaluating patients and treatment decisions in a multidisciplinary tumor board has led to better quality of care longer survival cancer patients. The aim this study was evaluate recommendations for thoracic oncology regarding guideline adherence transferal into clinical practice.We evaluated the at Ludwig-Maximilians University (LMU) Hospital Munich between 2014 2016. We compared patient characteristics guideline-adherent non-guideline-adherent recommendations, as well transferred...
Introduction Acute rejection is a significant risk factor for developing chronic lung allograft dysfunction. Current monitoring tools, transbronchial biopsies and HLA antibody determination, have limitations in detecting acute rejection. This study aims to explore the potential utility of donor-derived cell-free DNA (ddcfDNA) as non-invasive biomarker transplant recipients (LTR). Methods We developed molecular method based on digital droplet PCR determine total amount proportion ddcfDNA....
Aim To investigate central and peripheral nervous system activity muscle oxygenation in athletes during repeated-sprint exercise normoxia normobaric hypoxia.
BackgroundDocetaxel alone or in combination with ramucirumab nintedanib is recommended as second-line treatment metastatic non-small cell lung cancer (NSCLC) patients after progression on first-line platinum-base chemotherapy immune-checkpoint inhibitors (ICI). The purpose of our study was to compare the toxicity profile and efficacy docetaxel paclitaxel- pemetrexed-platinum ICI.Patients und MethodsMetastatic NSCLC treated pemetrexed paclitaxel-platinum without ICI were included...
In patients with COPD, it has not been comprehensively assessed whether the predictive value of comorbidities for mortality differs between men and women. We therefore aimed to examine sex differences COPD in regard prognosis by classifying into a comorbidome related extrapulmonary disorders pulmorbidome, referring pulmonary disorders. The study population comprised 1044 women 1531 diagnosis from COSYCONET, among them 2175 GOLD grades 1-4 400 at risk. Associations were studied using Cox...
Background Although lung cancer is most commonly diagnosed in elderly patients, evidence about tumor-directed therapy patients sparse, and it unclear to what extent this affects treatment care. Our study aimed discover potential disparities care between those under 65 years of age. Methods We studied claims from 13 283 German with 2009 who survived for at least 90 days after diagnosis. classified as "non-elderly" (≤ 65), "young-old" (65–74), "middle-old" (75–84), "old-old" (≥ 85). compared...
The occurrence of abnormal clumps epithelial cells in fibrotic lesions the lung has been long recognized.Pagel (1926) reviewed earlier references and gave first adequate description these bronchiectasis.He considered that they were metaplastic rather than neoplastic nature related to bronchiectasis.In contrast, Bert Fischer (1910) regarded their case as having origin an embryonic rest.Since then, however, inter- pretation significance varied considerably.They have either atypical...
LactobaciUus delbrueckii, strain 730 (ATCC 9649), is representative of a large group lactic acid bacteria that more fastidious in its nutri- tional requirements than are those organisms (e.g., LactobaciUs arabinosus, Strepcocus faecalis) commonly used for assay vitamins and amino acids.Previous nutritional investiga- tions with this organism (McNutt Snell, 1950; Kitay et al., 1950) showed it to require pyridoxamine phosphate, thymidine, an unsaturated fatty oleic acid) growth medium supplied...
Journal Article The tissue responses of the rat to implanted ivalon, etheron, and polyfoam plastic sponges Get access J B Walter, Walter Department Pathology, Royal College Surgeons England, Lincoln's Inn Fields, London, W.C.2, England Search for other works by this author on: Oxford Academic Google Scholar L G Chiaramonte British Surgery, Volume 52, Issue 1, January 1965, Pages 49–54, https://doi.org/10.1002/bjs.1800520112 Published: 08 December 2005
The novel coronavirus SARS-CoV-2 has caused a global COVID-19 pandemic, leading to worldwide changes in public health measures. In addition the sector (lockdowns, contact restrictions), hospitals modified care minimize risk of infection and mobilize resources for patients. Our study aimed assess impact these measures on access behaviour patients with thoracic malignancies. Thoracic oncology were surveyed October 2020 using paper-based questionnaires ambulatory services tumor-directed therapy...