A5052518690- Neurobiology and Insect Physiology Research
- DNA and Nucleic Acid Chemistry
- Metal complexes synthesis and properties
- Surfactants and Colloidal Systems
- Insect Resistance and Genetics
- Insect and Pesticide Research
- Chemical and Physical Properties in Aqueous Solutions
- Thermodynamic properties of mixtures
- Bioactive Compounds and Antitumor Agents
- Ionic liquids properties and applications
- Synthesis and biological activity
- Cancer therapeutics and mechanisms
- Inorganic and Organometallic Chemistry
- Synthesis of Tetrazole Derivatives
- Insect-Plant Interactions and Control
- Invertebrate Immune Response Mechanisms
- Building Energy and Comfort Optimization
- Enzyme function and inhibition
- Advanced NMR Techniques and Applications
- Protein Interaction Studies and Fluorescence Analysis
- Insect Utilization and Effects
- Synthesis and Biological Evaluation
- Analytical Chemistry and Chromatography
- Ferrocene Chemistry and Applications
- Insect Pest Control Strategies
National Institute of Technology Hamirpur
2015-2024
Himachal Pradesh University
2008
Indian Institute of Technology Roorkee
2003-2005
A Simple, convenient and highly efficient I 2 ‐catalysed approach has been unfolded towards the synthesis of fluorescent β‐carboline C‐1(3)‐tethered thiazolo[4,5‐ c ]carbazoles, naphtho[2,1‐ d ]thiazoles benzothiazole derivatives using Kumujian C as a template. This domino strategy proceeds through assembly 1‐formyl‐9 H ‐β‐carbolines, arylamines elemental sulfur via formation one C–N two C–S bonds in single operation. Importantly, methodology was found applicable to acetals also. diversely...
In order to achieve an optimal design, a comprehensive study at the molecular level between drug molecules and biological membranes is required. Investigation using both computational experimental methods on interaction ionic liquid 1-decyl-3-methylimidazolium bromide ([C10MIm][Br]) l-leucine/glycyl-l-leucine was conducted pressure of p = 0.1 MPa temperature that varied from 288.15 318.15 K. The density speed sound for mixtures l-leucine glycyl-l-leucine with water [C10MIm][Br] were...
Mitoxantrone is a promising antitumor drug having considerably reduced cardiotoxicity as compared to anthracyclines. Its binding deoxyhexanucleotides sequence d-(ATCGAT)2 has been studied by proton and phosphorous-31 nuclear magnetic resonance spectroscopy. The stoichiometry reveals that 1:1 2:1 mitoxantrone-d(ATCGAT)2 complexes are formed in solution. Significant upfield shifts 6H/7H, 2H/3H, 11NH, 12NH protons (∼.5 ppm) of mitoxantrone T6NH imino (∼.3 observed. phosphorous resonances do not...
Titanium(II) complexes of composition TiCl_2(L)_2 [where L = 2,2'-bipyridine (bipy), 4,4'-dimethyl-2,2'-bipyridine (bpMe), 4,4'-dimethoxy-2,2'-bipyridine (bpoMe), 6,6'-dimethyl-2,2'-bipyridine (dpMe), adamantylamine (ada)] were prepared by reacting titanium tetrachloride and N-containing bulky ligands in predetermined molar ratios. The synthesized characterized different spectroscopic techniques, viz. UV-visible, FTIR, ^1H NMR, mass spectrometry. stoichiometry the was established their...
Titanium complexes have been synthesized by the reaction between titanium tetrachloride (TiCl4), respective bidentate ligand [4,4' -dimethoxy-2,2' -bipyridine (bpome), 6,6'-dimethyl-2,2'-bipyridine (dpme), 1,2-diaminocyclohexane (dach), 1,10-phenanthroline (phen), and benzoylacetone (bzac)], adamantylamine (ada) in 1 : 2 molar ratios, respectively. The structure of was confirmed using elemental analysis, FTIR, UV-visible, (1)H NMR, mass spectrometry techniques. nanocrystalline nature powder...
Virtual screening of chemical databases has become an integral part ligand design.Docking is one the most important methods in computer assisted screening.If a three dimensional structure target receptor available, along with information regarding nature ligand-binding site, mode; interactions between and can be studied extensively, order to design develop specific new compounds short time period.Juvenile Hormone Analogues, sesqui-terpenoid series compound act as insect growth regulator,...
1, 4 and 5, 8-Positions as well type of functionalities on these positions at anthraquinone-9, 10-dione are proposed to be significant for anticancer activity. Therefore, keeping this into consideration, a series 1-substituted anthraquinone-based compounds designed, synthesized, characterized biologically evaluated The structure synthesized is confirmed by spectroscopic analysis, i.e. 1D (1H 13C) nuclear magnetic resonance (NMR), electrospray ionization-mass spectrometry (ESI-MS) studies...
Abstract In the present study, spectroscopic investigation of pyriproxyfen (PYR) has been carried out using density functional theory and experimental methods. The FT‐IR, 1 H 13 C NMR spectra PYR were recorded, interpreted compared with theoretical spectra. polarizability hyperpolarizabilities are responsible for higher lipophilicity which leads to acute aquatic toxicity molecule. UV‐Visible exhibited presence π π* transition between π‐orbitals phenoxyphenyl pyridyl ring. standard entropy,...
Juvenile hormone (JH) analogs are nowadays in use to control harmful pests. In order develop new bioactive molecules as potential pesticides, we have incorporated different active structural features like sulfonamide, aromatic rings, amide group, and amino acid moiety the base structure. We screened a series of designed novel JH against receptor protein (jhbpGm-2RCK) Galleria mellonella comparison commercial insect growth regulators (IGRs) – Pyriproxyfen (T1) Fenoxycarb (T2). All exhibit...
Juvabione, dehydrojuvabione and their aromatic analogues act as juvenile hormone mimics against diverse strains of insect species. Large numbers modified juvenoids containing the juvabione skeleton, with various structural variations, are synthesized. Some these compounds exhibit a very high degree activity presently in use. In this paper we report comparative molecular docking study synthesized juvabione, natural III synthetic growth regulators (fenoxycarb, S-21149, Compound 1,...