A5034197655- Stroke Rehabilitation and Recovery
- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Dementia and Cognitive Impairment Research
- Intensive Care Unit Cognitive Disorders
- Acute Ischemic Stroke Management
- Functional Brain Connectivity Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neurobiology of Language and Bilingualism
- Traumatic Brain Injury Research
- Psychotherapy Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Cerebral Palsy and Movement Disorders
- Mental Health Treatment and Access
- Mindfulness and Compassion Interventions
- Transcranial Magnetic Stimulation Studies
- Child and Adolescent Psychosocial and Emotional Development
- Multiple Sclerosis Research Studies
- Face Recognition and Perception
- Advanced MRI Techniques and Applications
- Parkinson's Disease Mechanisms and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Digital Mental Health Interventions
- Counseling Practices and Supervision
- Cognitive Functions and Memory
Weill Cornell Medicine
2017-2025
Cornell University
2017-2025
Presbyterian Hospital
2017-2024
New York Hospital Queens
2017-2024
NewYork–Presbyterian Hospital
2017-2024
Mercy University
2021
Foundation for Physical Medicine and Rehabilitation
2021
Boston University
2014-2016
Providence VA Medical Center
2016
Brown University
2016
Early reports and case series suggest cognitive deficits occurs in some patients with COVID-19. We evaluated the frequency, severity, profile of dysfunction recovering from prolonged COVID-19 hospitalization who required acute inpatient rehabilitation prior to discharge. analyzed cross-sectional scores Brief Memory Executive Test (BMET) a cohort N = 57 undergoing rehabilitation, calculating frequency impairment based on neuropsychologist diagnosis by age-normed BMET subtests. In total, 43...
White matter pathways between neurons facilitate neuronal coactivation patterns in the brain. Insight into how these structural and functional connections underlie complex cognitive functions provides an important foundation with which to delineate disease-related changes functioning. Here, we integrate neuroimaging, connectomics, machine learning approaches explore brain connectivity relate cognition. Specifically, evaluate extent predict individual crystallised fluid abilities 415...
Abstract Quantitative susceptibility mapping (QSM), an imaging technique sensitive to brain iron, has been used detect paramagnetic rims of iron-laden active microglia and macrophages in a subset multiple sclerosis (MS) lesions, known as rim+ that are consistent with chronic lesions. Because the potential impact lesions on disease progression tissue damage, investigating their influence disability neurodegeneration is critical establish these course. This study aimed explore relationship...
Importance The frequent occurrence of cognitive symptoms in post–COVID-19 condition has been described, but the nature these and their demographic functional factors are not well characterized generalizable populations. Objective To investigate prevalence self-reported condition, comparison with individuals prior acute SARS-CoV-2 infection who did develop association other individual features, including depressive status. Design, Setting, Participants Two waves a 50-state nonprobability...
To inform how emotions in speech are implicitly processed and registered memory, we compared emotional prosody, semantics, both cues tandem prime decisions about conjoined faces. Fifty-two participants rendered facial affect (Pell, 2005a), indicating whether a target face represented an emotion (happiness or sadness) not (a grimace), after passively listening to happy, sad, neutral utterances. Emotional information from primes was conveyed by: (1) prosody only; (2) semantic (3) combined...
White matter hyperintensities (WMH) represent ischemic white damage in late-life depression (LLD) and are associated with cognitive control dysfunction. Understanding the impact of WMH on structural connectivity gray correlates WMH-related dysconnectivity can provide insight into pathophysiology LLD. We compared burden performance clinical measures patients LLD (N = 44) a group non-depressed older adults 59). used Network Modification (NeMo) Tool to investigate specific regions, how such was...
In the spring of 2020, New York City was an epicenter coronavirus disease 2019 (COVID-19). The post-hospitalization needs COVID-19 patients were not understood and no outpatient rehabilitation programs had been described.To evaluate whether a virtual program would lead to improvements in strength cardiopulmonary endurance when compared with intervention discharged home persistent symptoms.Prospective cohort study.Academic medical center.Between April July 106 symptoms treated. Forty-four...
We examined biological motion perception in Parkinson's disease (PD). Biological is related to one's own motor function and depends on the integrity of brain areas affected PD, including posterior superior temporal sulcus. If deficits exist, they may be specific perceiving natural/fast walking patterns that individuals with PD can no longer perform, correlate disease-related dysfunction.Twenty-six nondemented 24 control participants viewed videos point-light walkers scrambled versions served...
Abstract Parkinson’s disease (PD) has several negative effects on speech production and communication. However, few studies have looked at how patterns in PD contribute to linguistic social impressions formed about patients from the perspective of listeners. In this study, discourse recordings elicited nondemented speakers ( n = 18) healthy controls 17) were presented 30 listeners unaware speakers’ status. separate conditions, rated samples based their speaker or content. Acoustic measures...
Diffusion tensor imaging along perivascular spaces (DTI-ALPS) is a novel MRI method for assessing brain interstitial fluid dynamics, potentially indexing glymphatic function. Failed clearance implicated in Alzheimer’s disease (AD) pathophysiology. We assessed the contribution of age and female sex (strong AD risk factors) to DTI-ALPS index healthy subjects. also first time effect head size. In accord with prior studies, we show reduced aging, men compared women. However, size may be major...
The aims of the study were to describe an interdisciplinary inpatient rehabilitation program for patients recovering from COVID-19 and evaluate functional outcomes.This is analysis retrospective data captured electronic health record admitted unit (N = 106). Rehabilitation approaches are described narratively. Functional gain was evaluated using Activity Measure Postacute Care 6 Clicks, basic mobility daily activities.Interdisciplinary implemented address medical, physical, communication,...
Cognitive impairment is increasingly recognized as a sequela of COVID-19. It unknown how cognition changes and relates to functional gain during inpatient rehabilitation. We administered the Montreal Assessment (MoCA) at admission 77 patients undergoing rehabilitation for COVID-19 in large US academic medical center. Forty-five were MoCA discharge. Functional was assessed by change quality indicator self-care (QI-SC). In full sample, 80.5% exhibited cognitive on admission, which associated...
A thorough understanding of sex-independent and sex-specific neurobiological features that underlie cognitive abilities in healthy individuals is essential for the study neurological illnesses which males females differentially experience exhibit impairment. Here, we evaluate relationships between functional connectivity individual 392 young adults (196 males) from Human Connectome Project. First, establish models comparably predict crystallised females, but only successfully fluid males....
Data regarding the prevalence and phenotype of cognitive impairment in non-alcoholic fatty liver disease (NAFLD) are limited.
Background: Our prior work demonstrated that estimated structural and functional connectomes (eSC eFC) generated using multiple sclerosis (MS) lesion masks artificial intelligence (AI) models can predict disability as effectively SC FC derived from diffusion MRI in MS. The goal of this study was to assess the ability eSC eFC predicting baseline 4-year follow-up cognition MS patients. Methods: One hundred seventy-one patients (age: 42.67 ± 10.41, 74% females) were included. Symbol Digit...
<title>Abstract</title> Our prior work demonstrated that estimated structural and functional connectomes (eSC eFC) generated using multiple sclerosis (MS) lesion masks artificial intelligence (AI) models can predict disability as effectively SC FC derived from diffusion MRI in MS. The goal of this study was to assess the ability eSC eFC predicting baseline 4-year follow-up cognition MS patients. Network Modification tool performed estimate clinical MRI-derived masks. then used an input...