A5036914421- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Transcranial Magnetic Stimulation Studies
- Dementia and Cognitive Impairment Research
- Treatment of Major Depression
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Neural and Behavioral Psychology Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural dynamics and brain function
- Digital Mental Health Interventions
- Mental Health Treatment and Access
- Stroke Rehabilitation and Recovery
- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- Health, Environment, Cognitive Aging
- Health disparities and outcomes
- Intensive Care Unit Cognitive Disorders
- EEG and Brain-Computer Interfaces
- Schizophrenia research and treatment
- Impact of Technology on Adolescents
- Neurobiology of Language and Bilingualism
- Tryptophan and brain disorders
Cornell University
2016-2025
Weill Cornell Medicine
2017-2025
Columbia University
2022
New York Hospital Queens
2016-2021
NewYork–Presbyterian Hospital
2014-2021
Presbyterian Hospital
2016-2021
Massachusetts General Hospital
2021
Harvard University
2021
Political Research Associates
2021
Mass General Brigham
2021
Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of human brain. However, no reference standards currently exist to quantify individual differences metrics over time, contrast growth charts for anthropometric traits such as height weight
Early reports and case series suggest cognitive deficits occurs in some patients with COVID-19. We evaluated the frequency, severity, profile of dysfunction recovering from prolonged COVID-19 hospitalization who required acute inpatient rehabilitation prior to discharge. analyzed cross-sectional scores Brief Memory Executive Test (BMET) a cohort N = 57 undergoing rehabilitation, calculating frequency impairment based on neuropsychologist diagnosis by age-normed BMET subtests. In total, 43...
Resting-state functional magnetic resonance imaging (fMRI) is widely used in cognitive and clinical neuroscience, but long-duration scans are currently needed to reliably characterize individual differences connectivity (FC) brain network topology. In this report, we demonstrate that multi-echo fMRI can improve the reliability of FC-based measurements. four densely sampled humans, just 10 min data yielded better test-retest than 30 single-echo independent datasets. This effect pronounced...
Article abstract—We examined the pattern of neuroanatomic abnormalities in adults with Down9s syndrome (DS) and cognitive correlates these abnormalities. Specifically, we compared this what would be predicted by hypotheses attributing DS pathology to either premature aging or Alzheimer9s disease. We measured a number brain regions on MRIs 25 subjects: 13 persons phenotype 12 age- sex-matched healthy volunteers. Study participants had no history cardiovascular disease, diabetes, thyroid...
Background Existing treatments for depression are known to have only modest effects, insufficiently targeted, and inconsistently utilized, particularly in older adults. Indeed, adults with impaired cognitive control networks tend demonstrate poor response a majority of existing interventions. Cognitive interventions delivered using entertainment software the potential not target underlying cerebral dysfunction associated depression, but do so manner that is engaging engenders adherence...
Transcranial magnetic stimulation (TMS) is used to treat multiple psychiatric and neurological conditions by manipulating activity in particular brain networks circuits, but individual responses are highly variable. In clinical settings, TMS coil placement typically based on either group average functional maps or scalp heuristics. Here, we found that this approach can inadvertently target different depressed patients due variability their organization. More precise targeting should be...
Importance The frequent occurrence of cognitive symptoms in post–COVID-19 condition has been described, but the nature these and their demographic functional factors are not well characterized generalizable populations. Objective To investigate prevalence self-reported condition, comparison with individuals prior acute SARS-CoV-2 infection who did develop association other individual features, including depressive status. Design, Setting, Participants Two waves a 50-state nonprobability...
Abstract Background Structural abnormalities of the anterior cingulate cortex (ACC) may interfere with interaction cortical and limbic networks involved in emotional regulation contribute to chronic depressive syndromes elderly. This study examined relationship regional volumes treatment remission elderly depressed patients. We hypothesized that patients who failed remit during a 12‐week controlled trial escitalopram would exhibit smaller gray matter than remitted. Methods The participants...
White matter hyperintensities (WMH) represent ischemic white damage in late-life depression (LLD) and are associated with cognitive control dysfunction. Understanding the impact of WMH on structural connectivity gray correlates WMH-related dysconnectivity can provide insight into pathophysiology LLD. We compared burden performance clinical measures patients LLD (N = 44) a group non-depressed older adults 59). used Network Modification (NeMo) Tool to investigate specific regions, how such was...