- Breast Cancer Treatment Studies
- Breast Implant and Reconstruction
- Advanced Breast Cancer Therapies
- Digital Radiography and Breast Imaging
- Medical Imaging Techniques and Applications
- Breast Lesions and Carcinomas
- Cancer Treatment and Pharmacology
- Reconstructive Surgery and Microvascular Techniques
- Radiomics and Machine Learning in Medical Imaging
- Cancer Diagnosis and Treatment
- AI in cancer detection
- Global Cancer Incidence and Screening
- Digital Imaging in Medicine
- Tissue Engineering and Regenerative Medicine
- Cancer Genomics and Diagnostics
- HER2/EGFR in Cancer Research
- Head and Neck Cancer Studies
- Lung Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Male Breast Health Studies
- BRCA gene mutations in cancer
- Tattoo and Body Piercing Complications
- Cancer Risks and Factors
- Advances in Oncology and Radiotherapy
- Cancer survivorship and care
University Hospital Foundation
2025
Prince Philip Hospital
2014-2024
University of Bristol
2024
Hywel Dda University Health Board
2018-2023
First Hospital of Jilin University
2011
Jilin University
2011
Henry Ford Hospital
2011
Délégation Centre-Est
2008
Tumour gene expression analysis is useful in predicting adjuvant chemotherapy benefit early breast cancer patients. This study aims to examine the implications of routine Oncotype DX testing UK. Women with oestrogen receptor positive (ER+), pNO or pN1mi were assessed for and subsequently offered testing, changes decisions recorded. A subset patients completed questionnaires about their uncertainties regarding pre- post-testing. All asked complete a diary medical interactions over next 6...
Abstract Purpose UK NICE guidelines recommend axillary node clearance (ANC) should be performed in all patients with biopsy-proven node-positive breast cancer having primary surgery. There is, however, increasing evidence such extensive surgery may not always necessary. Targeted dissection (TAD) an effective alternative low-volume nodal disease who are clinically negative (cN0) but have abnormal nodes detected radiologically. This survey aimed to explore current management of this group...
Treatment of early breast cancer in older women is usually not guideline concordant owing to lack routine evaluation their potential frailty. We assessed the feasibility and impact a self-administered geriatric assessment on decision-making process aged 65 above treated UK District General Hospital.One hundred one patients, above, with stage, non-metastatic were prospectively recruited between Dec-2018 March-2021. Patients metastatic cancer, previous history dementia excluded. All patients...
Background: The goal of breast conserving surgery is to achieve complete excision the tumor with adequate surgical margins, while preserving natural shape and appearance breast. This a retrospective study which compared operative outcomes in oncoplastic (OPS; n=54) versus standard wide local (WLE; n=265) populations. A total 319 consecutive patients were included study. primary size tumor, weight specimen margin clearance. secondary patient satisfaction, recurrence rates time. Methods:...
Abstract Introduction: The incidence of breast cancer in the under 40-year-old age group is approximately 7% (Anders et al., 2009). Studies suggests that management Breast adolescent and young women more challenging, with this under-represented clinical trials. We investigated outcomes a cohort 98 patients seen between 2013 2023 Hywel Dda NHS University Health Board, Wales, UK. Methods: A retrospective review was performed. Demographic, surgical outcome data for 40 years collated analysed....
Abstract Introduction: The addition of adjuvant chemotherapy to hormonal therapy is recommended for patients with lymph node-positive (LN+ve), estrogen receptor positive (ER+), HER2-ve early breast cancer, despite the fact that many women will remain disease-free even if they do not receive chemotherapy. Therefore, a number LN+ EBC may be unnecessarily exposed toxicities no treatment benefit. In UK, Oncotype DX® Recurrence Score (RS) by NICE routine testing in ER+ HER2-ve, node negative...
We present a case of wound dehiscence in patient with clinical features herpes zoster.A 44 year old woman, history recurrent zoster infection, presented to the accident and emergency department extrusion left sided tear-drop shaped euro-silicone breast implant from an surgical scar. A month prior admission, this had developed unilateral crops vesicles along scar which was apposing her infra-mammary fold. This preceded by fatigue neuralgia. Histology revealed acute inflammation related...
Background: Estimating the size and volume of breast preoperatively is an important step in surgical planning for many procedures such as immediate implant-based reconstructions reduction mammoplasties. Breast estimation helps appropriate implant selection preoperatively. Objectives: The aim this study was to objectively evaluate weight by automatic volumetric assessment digital tomosynthesis (DBT) using Quantra™ 2.2 Density Assessment Software (Hologic Inc., Marlborough, Massachusetts,...
To explore the long-term outcome of patients who underwent Oncotype DX® testing. The relationship between RS, adjuvant treatments received, and clinical outcomes across entire range RS results are reported.10-year Kaplan-Meier estimates for distant recurrence/BC-specific survival (BCSS) in this cohort. analysis included 439 patients. follow-up time ranged from 14 to 142 months. All analyses were performed using SPSS v20.More than half had low (<18) (55.6%) 15.3% ≥ 31. Chemotherapy use was...