A5041194050- Lipid Membrane Structure and Behavior
- Heme Oxygenase-1 and Carbon Monoxide
- Connexins and lens biology
- Surfactants and Colloidal Systems
- Analytical Chemistry and Sensors
- Spectroscopy and Quantum Chemical Studies
- Hemoglobin structure and function
- Porphyrin and Phthalocyanine Chemistry
- Lipid metabolism and biosynthesis
- Plasma Applications and Diagnostics
- Heat shock proteins research
- Photodynamic Therapy Research Studies
- Molecular Sensors and Ion Detection
- Mass Spectrometry Techniques and Applications
- Nicotinic Acetylcholine Receptors Study
- Nanopore and Nanochannel Transport Studies
- Muscle metabolism and nutrition
- Nanoplatforms for cancer theranostics
- RNA Interference and Gene Delivery
University of Antwerp
2021-2023
Universidade Federal do ABC
2018-2022
Although the general mechanisms of lipid oxidation are known, chemical steps through which photosensitizers and light permeabilize membranes still poorly understood. Herein we characterized products photooxidation their effects on bilayers, also giving insight into formation pathways. Our experimental system was designed to allow two phenothiazinium-based (methylene blue, MB, DO15) deliver same amount singlet oxygen molecules per second 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine...
The potential of cold atmospheric plasma (CAP) in biomedical applications has received significant interest, due to its ability generate reactive oxygen and nitrogen species (RONS). Upon exposure living cells, CAP triggers alterations various cellular components, such as the cell membrane. However, permeation RONS across nitrated oxidized membranes remains understudied. To address this gap, we conducted molecular dynamics simulations, investigate capabilities modified membranes. This...
Lipid oxidation is associated with several inflammatory and neurodegenerative diseases, but many questions to unravel its effects on biomembranes are still open due the complexity of topic. For instance, recent studies indicated that phase-separated domains can have a significant effect membrane function. It reported domain interfaces "hot spots" for pore formation, underlying mechanisms oxidation-induced phase separation membranes remain elusive. Thus, evaluate permeability coexisting...