A5085518937- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Diet and metabolism studies
- Birth, Development, and Health
- Nutrition, Genetics, and Disease
- Agriculture Sustainability and Environmental Impact
- Eating Disorders and Behaviors
- Genetic Associations and Epidemiology
- Liver Disease Diagnosis and Treatment
- Consumer Attitudes and Food Labeling
- Diet, Metabolism, and Disease
- Metabolomics and Mass Spectrometry Studies
- Food Security and Health in Diverse Populations
- Cognitive Abilities and Testing
- Adipose Tissue and Metabolism
- Health and Lifestyle Studies
- Fatty Acid Research and Health
- Health, Environment, Cognitive Aging
- Regulation of Appetite and Obesity
- Bone health and osteoporosis research
- Dietary Effects on Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Assisted Reproductive Technology and Twin Pregnancy
- Diabetes Treatment and Management
- Circadian rhythm and melatonin
Bern University of Applied Sciences
2023-2025
Institute for Molecular Medicine Finland
2009-2025
University of Helsinki
2015-2025
Medical University of Vienna
2019-2024
Leibniz Institute for Prevention Research and Epidemiology - BIPS
2017-2020
Kinokuniya
2019
Cambridge University Press
2019
New York University Press
2019
QIMR Berghofer Medical Research Institute
2019
Hospital Universitário da Universidade de São Paulo
2019
The aim of this study was to determine whether an association exists between children’s and parental dietary patterns (DP), the number shared meals or soft drink availability during strengthens association. In 2013/2014 I.Family cross‐sectionally assessed intakes families from eight European countries using 24‐h recalls. Usual energy food six‐ 16‐year‐old children their parents were estimated based on NCI Method. A total 1662 child–mother 789 child–father dyads included; DP derived cluster...
Overconsumption of dietary sugars, fructose in particular, is linked to cardiovascular risk factors such as type 2 diabetes, obesity, dyslipidemia and nonalcoholic fatty liver disease. However, clinical studies have date not clarified whether these adverse cardiometabolic effects are induced directly by or they secondary weight gain.To assess the (75 g day-1 ), served with their habitual diet over 12 weeks, on fat content other a large cohort (n = 71) abdominally obese men.We analysed...
Abstract Background Childhood obesity is a complex multifaceted condition, which influenced by genetics, environmental factors, and their interaction. However, these interactions have mainly been studied in twin studies evidence from population-based cohorts limited. Here, we analyze the interaction of an obesity-related genome-wide polygenic risk score (PRS) with sociodemographic lifestyle factors for BMI waist circumference (WC) European children adolescents. Methods The analyses are based...
Information on familial resemblance is important for the design of effective family-based interventions. We aimed to quantify correlations and estimate proportion variation attributable genetic shared environmental effects (i.e., familiality) dietary intake variables determine whether they vary by generation, sex, quality, or age children. The study sample consisted 1435 families (1007 mothers, 438 fathers, 1035 daughters, 1080 sons) from multi-center I.Family study. Dietary was assessed in...
OBJECTIVE Impaired incretin response represents an early and uniform defect in type 2 diabetes, but the contributions of genes environment are poorly characterized. RESEARCH DESIGN AND METHODS We studied 35 monozygotic (MZ) 75 dizygotic (DZ) twin pairs (discordant concordant for obesity) to determine heritability glucagon-like peptide 1 (GLP-1) responses oral glucose tolerance test (OGTT) influence acquired obesity GLP-1, glucose-dependent insulinotropic (GIP), YY (PYY) during OGTT or meal...
Abstract Breast cancer is highly prevalent yet a more complete understanding of the interplay between genes and probable environmental risk factors, such as night work, remains lagging. Using discordant twin pair design, we examined association shift work breast risk, controlling for familial confounding. Shift pattern was prospectively assessed by mailed questionnaires among 5,781 female twins from Older Finnish Twin Cohort. Over study period (1990–2018), 407 incident cases were recorded...
The purpose of this study was to investigate the relationship fat mass (FM) and lean (LM) with bone mineral density (BMD) independent genetic effects. We also assessed extent which environmental influences explain associations between these phenotypes. Body composition BMD were measured using dual-energy X-ray absorptiometry in 57 monozygotic 92 same-sex dizygotic twin pairs, aged 23 31 years, chosen represent a wide range intrapair differences body index (BMI; 0 15.2 kg/m(2)). Heritability...
ABSTRACT Introduction Plant‐based dietary patterns may reduce the risk of chronic diseases, but their benefits and risks in younger populations remain unclear due to variations diet quality nutrient adequacy. Robust tools assess adherence these are essential. The aim this study was develop validate three plant‐based propensity (PBDP) scores – overall, healthy unhealthy capture associations with intakes health indicators children, adolescents adults. Methods This cross‐sectional adults used...
Abstract Background Socioeconomic disparities in dietary behaviors are well-known, but underlying mechanisms not fully understood. We investigated whether consumer attitudes toward mediate the relationship between socioeconomic factors and diet quality. Methods This analysis included 4051 adult participants from eight European countries of I.Family study (2013/2014). Dietary intake was assessed using a food frequency questionnaire, quality measured by adherence to recommendations Healthy...
Summary Background and Objectives To examine whether changes in the Mediterranean Diet (MD) or any of its MD food groups modulate genetic susceptibility to obesity European youth, both cross‐sectional longitudinal analyses. Methods For analysis, 1982 participants at baseline, 1649 follow‐up 1 (FU1) 1907 2 (FU2), aged 2–16 years IDEFICS/I.Family studies were considered. design, 1254 included. Adherence was assessed using Score (MDS), high BMI with a polygenic risk score (BMI‐PRS). Multiple...
Abstract Background Lifestyle interventions to prevent paediatric obesity often target family and peer settings; their success is likely depend on the influence that peers families exert children’s lifestyle behaviors at different developmental stages. Objective First, determine whether behavior more closely resembles peers’ or siblings’ behaviors. Secondly, investigate longitudinally behavioral change predicted by of siblings as they grow older. Methods The European prospective...
Meal timing has been associated with metabolic markers in adults, but not children or adolescents. The aim of this study was to investigate associations meal patterns (MTPs) insulin resistance (IR) and triglyceride levels In cross-sectional study, we included 2,195 participants aged 8–15 years from the European I.Family (2013/14). Habitual diet exposures were derived using 24-hr dietary recalls HOMA-IR, HbA1c, triglycerides used as outcome variables. We applied k-means cluster analysis on...
A trend toward greater body size in dizygotic (DZ) than monozygotic (MZ) twins has been suggested by some but not all studies, and this difference may also vary age. We analyzed zygosity differences mean values variances of height mass index (BMI) among male female from infancy to old Data were derived an international database 54 twin cohorts participating the COllaborative project Development Anthropometrical measures Twins (CODATwins), included 842,951 BMI measurements aged 1 102 years....
It is well established that boys are born heavier and longer than girls, but it remains unclear whether birth size in twins affected by the sex of their co-twin. We conducted an individual-based pooled analysis 21 twin cohorts 15 countries derived from COllaborative project Development Anthropometrical measures Twins (CODATwins), including 67,850 dizygotic individuals. Linear regression analyses showed having a co-twin sister were, on average, 31 g (95% CI 18 to 45) 0.16 cm 0.045 0.274)...
Abstract The COllaborative project of Development Anthropometrical measures in Twins (CODATwins) is a large international collaborative effort to analyze individual-level phenotype data from twins multiple cohorts different environments. main objective study factors that modify genetic and environmental variation height, body mass index (BMI, kg/m 2 ) size at birth, additionally address other research questions such as long-term consequences birth size. started 2013 open all twin projects...
There has been an increase in children growing up non-traditional families, such as single-parent and blended families. Children from families have a higher prevalence of obesity poorer health outcomes, but research on the relationship with obesogenic behaviours is limited.