Anna K. Dahl Aslan
- Birth, Development, and Health
- Nutritional Studies and Diet
- Geriatric Care and Nursing Homes
- Frailty in Older Adults
- Nutrition and Health in Aging
- Cognitive Abilities and Testing
- Diet and metabolism studies
- Obesity, Physical Activity, Diet
- Health, Environment, Cognitive Aging
- Dementia and Cognitive Impairment Research
- Genetic Associations and Epidemiology
- Health disparities and outcomes
- Aging and Gerontology Research
- Epigenetics and DNA Methylation
- Health Systems, Economic Evaluations, Quality of Life
- Assisted Reproductive Technology and Twin Pregnancy
- Cardiovascular Health and Risk Factors
- Interprofessional Education and Collaboration
- Sleep and Work-Related Fatigue
- Global Health Care Issues
- Nutrition, Genetics, and Disease
- Retirement, Disability, and Employment
- Intergenerational Family Dynamics and Caregiving
- Smoking Behavior and Cessation
- Diabetes, Cardiovascular Risks, and Lipoproteins
University of Skövde
2021-2025
Jönköping University
2014-2024
Karolinska Institutet
2014-2022
King's College London
2021
University of California, Riverside
2021
Southern California University for Professional Studies
2021
University of Southern California
2021
Research Network (United States)
2018
Background: few studies have examined associations of multi-faceted demographic, health and lifestyle factors with long-term change in grip strength performance across the adult lifespan. The aim this study was to examine risk specific parts lifespan (e.g. early midlife, late midlife old adulthood) separately for women men. Methods: data came from longitudinal Swedish Adoption/Twin Study Aging (SATSA). Grip followed 849 participants who were 50–88 years age at baseline. follow-up period...
Objectives:Both physical functioning and cognitive abilities are important for well-being, not least in old age. Grip strength is often considered an indicator of general vitality and, as such, may predict functioning. Few longitudinal studies have examined the relationship between grip cognition, especially where specific been targeted.
Abstract We investigated the heritability of educational attainment and how it differed between birth cohorts cultural–geographic regions. A classical twin design was applied to pooled data from 28 representing 16 countries including 193,518 twins with information on at 25 years age or older. Genetic factors explained major part individual differences in (heritability: a 2 = 0.43; 0.41–0.44), but also environmental variation shared by co-twins substantial (c 0.31; 0.30–0.33). The proportions...
Background: Population-based health registers are potential assets in epidemiological research; however, the quality of case ascertainment is crucial. Objective: To compare dementia, from National Patient Register (NPR) and Cause Death (CDR) with dementia diagnoses six Swedish population based studies. Methods: Sensitivity, specificity, positive predictive value (PPV) identification NPR CDR were estimated by individual record linkage studies ( n = 19,035). Time to detection was using data on...
Although research has shown that sleep disorders are prevalent among people with dementia, the temporal relationship is unclear. We investigated whether atypical characteristics were associated incident dementia while accounting for baseline cognitive functioning. Screening Across Lifespan Twin (SALT) study participants 11,247 individuals from Swedish Registry who at least 65 years (1998-2002). Sleep and functioning assessed via SALT telephone screening interview. Data on diagnoses came...
Background Smokers tend to weigh less than never smokers, while successful quitting leads an increase in body weight. Because smokers and non-smokers may differ genetic environmental family background, we analysed data from twin pairs which the co-twins differed by their smoking behaviour evaluate if association between mass index (BMI) remains after controlling for background. Methods findings The international CODATwins database includes information on BMI measured 1960 2012 156,593...
This study aimed to investigate the association between shift work and incident dementia in two population-based cohorts from Swedish Twin Registry (STR). The STR-1973 sample included 13,283 participants born 1926–1943 who received a mailed questionnaire 1973 that asked about status (ever/never) duration (years) of employment. Screening Across Lifespan (SALT) 41,199 1900–1958 participated telephone interview 1998–2002 night duration. Dementia diagnoses came patient registers. Cox...
For over 100 years, the genetics of human anthropometric traits has attracted scientific interest. In particular, height and body mass index (BMI, calculated as kg/m 2 ) have been under intensive genetic research. However, it is still largely unknown whether how heritability estimates vary between populations. Opportunities to address this question increased recently because establishment many new twin cohorts increasing accumulation data in established cohorts. We started a research project...
Abstract Body mass index (BMI) is associated with cognitive abilities, but the nature of relationship remains largely unexplored. We aimed to investigate bidirectional from midlife through late-life, while considering sex differences and genetic predisposition higher BMI. used data 23,892 individuals European ancestry Health Retirement Study, longitudinal on BMI three established indices: mental status, episodic memory, their sum, called total cognition. To dynamic between we applied dual...
Although evidence indicates that Type II Diabetes is related to abnormal brain aging, the influence of elevated blood glucose on long-term cognitive change unclear. In addition, relationship between diet-based glycemic load and aging has not been extensively studied. The focus this study was investigate in older adults followed for up 16 years. Eight-hundred thirty-eight cognitively healthy aged ≥50 years (M = 63.1, SD 8.3) from Swedish Adoption/Twin Study Aging were Mixed effects growth...
Background/objectives: the association between late-life obesity and cognitive abilities is poorly understood. We studied body mass index (BMI) change in longitudinal population-based study spanning over ninth decade of life. Subjects/methods: total, 475 participants free dementia at baseline from Lothian Birth Cohort 1921 (mean age: 79.1 years, SD: 0.6) were included. Height weight assessed baseline. BMI was calculated as kg/m2. Cognitive age ∼11 years ∼79, ∼83, ∼87 ∼90 years. Results:...
Abstract Background Frailty is a strong predictor of adverse outcomes. However, longitudinal drivers frailty are not well understood. This study aimed at investigating the trajectories index (FI) from adulthood to late life and identifying factors associated with level rate change in FI. Methods An age-based latent growth curve analysis was performed Swedish Adoption/Twin Study Aging (N = 1,842; aged 29–102 years) using data up 15 measurement waves across 27 years. A 42-item FI used measure...
frailty shows an upward trajectory with age, and higher levels increase the risk of mortality. However, it is less known whether shape trajectories differs by age at death or rate change in associated mortality.to assess population to analyse current level index (FI) i.e. most recent measurement person-specific more predictive mortality.3,689 individuals from three population-based cohorts up 15 repeated measurements Rockwood were analysed. The FI assessed stratifying sample into four...
Significance There is a previously well-established relationship between socioeconomic status and cognitive ability. By having access to repeated measures of data across the second part life span, we were able not only study influence childhood social class on mean-level performance, but also change over time. Using reared-apart monozygotic dizygotic twins control sample reared together, studied effects environment cognition in later life. We found an association mean levels longitudinal...
Hospitalisation of nursing home residents might lead to deteriorating health.To evaluate physical and psychological factors associated with hospitalisation risk among residents.Prospective study three years follow-up.Four hundred twenty-nine Swedish residents, ages 65-101 years, from 11 homes in municipalities were followed during years. The participants' status was assessed at baseline. A Cox proportional hazards model used using STATA.Of the 429 participants, 196 (45.7%) hospitalised least...
Abstract Background While a high body mass index (BMI) in midlife is associated with higher risk of dementia, BMI late-life may be lower risk. This study combined genetic designs longitudinal data to achieve better understanding this paradox. Methods We used from 22,156 individuals the Swedish Twin Registry (STR) and 25,698 Health Retirement Study (HRS). The STR sample had information about early adulthood through late-life, HRS age 50 late-life. Survival analysis was applied investigate...
Diabetes has been linked to dementia risk; however, the cognitive trajectories in older adults with diabetes remain unclear. We aimed investigate effect of prediabetes and on among cognitively intact a long-term follow-up study. Within Swedish Adoption/Twin Study Aging, 793 aged ≥50 were identified at baseline followed for up 23 years. Based standardized scores from 11 tests, administered seven follow-ups, four domains (verbal abilities, spatial/fluid, memory, perceptual speed) by...
Objectives The few studies of shift work and late life cognitive functioning have yielded mixed findings. aim the present study is to estimate association between shift-work experience change in performance before after retirement age among older adults who were gainfully employed. Methods Five hundred ninety five participants with no dementia followed up for a mean 17.6 standard deviation (SD) 8.8 years from Swedish population-based sample. Participants had self-reported information on any...
A trend toward greater body size in dizygotic (DZ) than monozygotic (MZ) twins has been suggested by some but not all studies, and this difference may also vary age. We analyzed zygosity differences mean values variances of height mass index (BMI) among male female from infancy to old Data were derived an international database 54 twin cohorts participating the COllaborative project Development Anthropometrical measures Twins (CODATwins), included 842,951 BMI measurements aged 1 102 years....
Hospital readmissions of older persons are common and often associated with complex health problems. The objectives were to analyze risk factors for readmission within 30 days from hospital discharge.A prospective study a multifactorial approach based on the population-based longitudinal Swedish Adoption/Twin Study Aging (SATSA) was conducted. During 9 years follow-up, information hospitalizations, diagnoses obtained national registers. Logistic regression models controlling age sex...
Abstract The COllaborative project of Development Anthropometrical measures in Twins (CODATwins) is a large international collaborative effort to analyze individual-level phenotype data from twins multiple cohorts different environments. main objective study factors that modify genetic and environmental variation height, body mass index (BMI, kg/m 2 ) size at birth, additionally address other research questions such as long-term consequences birth size. started 2013 open all twin projects...