Synthetic polymer-based antimicrobial materials destroy conventional antibiotic resistant microorganisms. Although these antibacterial polymers imitate the properties of peptides (AMPs), their effect on bacterial cell morphology has not been studied in detail. To investigate change a presence polymer, herein we have designed and synthesized side-chain amino acid-based cationic polymers, which showed efficient activity against Gram-negative (Escherichia coli), as well Gram-positive (Bacillus...

β-Glucosidase (BG) catalyzes the hydrolysis of cellobiose to glucose and is a rate-limiting enzyme in conversion lignocellulosic biomass sugars toward biofuels. Since cost major contributor biofuel economics, we report bioconjugation temperature-responsive polymer with highly active thermophilic β-glucosidase (B8CYA8) from Halothermothrix orenii improving recyclability. The bioconjugate, lower critical solution temperature (LCST) 33 °C withstands high temperatures up 70 °C. Though secondary...

To evaluate the comparative antibacterial activity of leucine-based cationic polymers having linear, hyperbranched, and star architectures containing both hydrophilic hydrophobic segments against Gram-negative bacterium, Escherichia coli (E. coli), herein we performed zone inhibition study, minimum inhibitory concentration (MIC) calculation, bacterial growth experiment. The highest in terms MIC value was found hyperbranched because greater extent functionality, enhancing cell wall...

A single step process of integrating a resonantly tuned silver nanoparticle into photonic crystal nanobeam cavities fabricated by focused ion beam milling is presented. Even though the quality factor reduced 20, emission peak at cavity resonance enhanced 5-fold with respect to without metal nanoparticle. The fluorescence also compared before and after etching away Experimental factors wavelength shifts are found agree reasonably well simulation values. These results promising for future...

The design of a new drug material through modification some well-known antibiotics to combat pathogenic bacteria must include complete understanding matrix regulation because the human body consists primarily three types matrices, that is, solid, semisolid, and liquid, all which have tendency regulate antibacterial efficacy along with bactericidal mechanism several antimicrobial agents. Herein, matrix-dependent action ciprofloxacin-based polymeric hydrogel scaffold was explored against...

We report the comparative antibacterial activity of a polymer–antibiotic conjugate with coupled bioactive (cationic) and biopassive (zwitterionic) functionalities against several biofilm nonbiofilm forming bacterial species in both liquid solid matrices.

Molecular assembly of weakly pi-stacking core-substituted naphthalene diimides (cNDIs) requires the participation strong side-group interactions. Spatial confinement within a micellar core leads to locally elevated concentrations and reduced entropy that drives rapid aggregation, often followed by slower aggregate reorganization. Fast aggregation kinetics self-sorting aggregates.

Polyhedral oligomeric silsesquioxane (POSS) semitelechelic Aβ_17–19 peptide which initiated polymerization of γ-benzyl <sc>l</sc>-glutamate <italic>N</italic>-carboxyanhydride (BLG-NCA) was studied to prepare peptide–polypeptide conjugates with α-helical conformation.

Hydrogels are three-dimensional, hydrophilic, polymeric frameworks, constructed through diverse physical or chemical crosslinks. Recent research focuses on their physiological stimuli sensitivity enhancing bioapplications. Biopolymers with responsiveness to local environment like temperature, pH etc. form the foundation in this regard, around which all major natural processes circulated. Polysaccharides, being most abundant biopolymers and essential constituent of our daily food cereals...

A perturbation theory approach for the analysis of hybrid plasmonic- photonic crystal structures is presented. This allows accurate calculation resonance frequency shift and quality factor change when introducing a resonant plasmonic structure into microcavity. An example shown, agreeing to within 5% with comprehensive finite difference time domain simulations but taking an order magnitude less time. theoretical overcomes challenge poor scaling in computations plasmonic-photonic structures,...

The interfacial proton exchange detected by NMR is shown to provide insights into micellar aggregation process.

A perylene–porphyrin based novel microporous quasi-2D crystalline covalent organic framework (PETA-PAM-COF) shows high surface area and exceptional stability also used as a metal-free electrocatalyst for the hydrogen evolution reaction.

We present the simulation results, fabrication and measurements of a Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> N xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> nanobeam cavity as first step obtaining enhanced single photon emission from quantum emitters in photonic crystal incorporating metal nanoparticle. The is designed to resonate at operating wavelength CdSe dot emitter. use focused ion beam (FIB) milling one process...

A novel traditional fluorophore free bright blue light emitting small organic molecule with aqueous solubility consisting N-substituted maleimide zwitterionic side chain was explored. The combined experimental and theoretical studies revealed that the fluorescence originated due to aggregation of molecules named N-(ethyl sulfobetaine) (M) in solution. It also observed induced emission (AIE) after certain threshold concentration which confirmed by both experiment first principal calculations....

Polysaccharide is one of the most ancient and vast research field among natural sustainable biopolymers they are readily available in nature as an essential component our daily food. Hence, distribution entire into some important factor-based classification like physical structure, stability, solubility become mandatory for clear understanding whole polysaccharide chemistry. In past decades, scientists mainly focused on general laboratory synthesis this with potential applications. Then,...