Linda Meta Mobula

ORCID: 0000-0003-4319-2308
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About
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Research Areas
  • Blood Pressure and Hypertension Studies
  • Health Systems, Economic Evaluations, Quality of Life
  • Pharmaceutical Economics and Policy
  • Disaster Response and Management
  • Viral Infections and Outbreaks Research
  • COVID-19 epidemiological studies
  • Healthcare Systems and Reforms
  • Acute Ischemic Stroke Management
  • Chronic Kidney Disease and Diabetes
  • Medication Adherence and Compliance
  • Climate Change and Health Impacts
  • Biotechnology and Related Fields
  • Sodium Intake and Health
  • Global Security and Public Health
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cultural Competency in Health Care
  • COVID-19 diagnosis using AI
  • COVID-19 and healthcare impacts
  • Non-Invasive Vital Sign Monitoring
  • HIV/AIDS drug development and treatment
  • Global Health Workforce Issues
  • Malaria Research and Control
  • Mobile Health and mHealth Applications
  • Cardiovascular Health and Disease Prevention
  • Diabetes Management and Research

World Bank Group
2020-2025

Johns Hopkins University
2013-2022

Johns Hopkins Medicine
2014-2022

United States Agency for International Development
2015-2018

AIDS United
2015

San Francisco General Hospital
2009

The burden of uncontrolled hypertension in Low-and-Middle Income Countries (LMICs) is high, with an increased risk cardiovascular diseases and chronic renal failure these settings.To assess the factors associated blood pressure control a cross-section Ghanaian hypertensive subjects involved on-going multicenter epidemiological study aimed at improving access to treatment.A cross-sectional involving 2,870 participants or without diabetes who were enrolled 5 hospitals Ghana (2 tertiary, 2...

10.1371/journal.pone.0193494 article EN public-domain PLoS ONE 2018-03-19

Abstract The burden of chronic kidney disease (CKD) is rapidly rising in developing countries due to astronomical increases key risk factors including hypertension and diabetes. We sought assess the predictors CKD among Ghanaians with and/or diabetes mellitus a multicenter hospital‐based study. conducted cross‐sectional study Ghana Access Affordability Program (GAAP) involving adults only (HPT), (HPT + DM), (DM) 5 health facilities Ghana. A structured questionnaire was administered collect...

10.1111/jch.13672 article EN Journal of Clinical Hypertension 2019-08-29

The tenth outbreak of Ebola virus disease (EVD) in North Kivu, the Democratic Republic Congo (DRC), was declared 8 days after end ninth EVD outbreak, Equateur Province on August 1, 2018. With a total 3,461 confirmed and probable cases, Kivu second largest that West Africa 2014-2016, observed DRC. This difficult to control because multiple challenges, including armed conflict, population displacement, movement contacts, community mistrust, high density. It took more than 21 months with...

10.4269/ajtmh.20-0256 article EN other-oa American Journal of Tropical Medicine and Hygiene 2020-05-20

As of June 11, 2020, the Democratic Republic Congo (DRC) has reported 4,258 COVID-19 cases with 90 deaths. With other African countries, DRC faces challenge striking a balance between easing public health lockdown measures to curtail spread SARS-CoV-2 and minimizing both economic hardships for large sectors population negative impacts on services infectious noninfectious diseases. The recently controlled its tenth Ebola virus disease (EVD) outbreak, but new EVD outbreak beginning 1, 2020 in...

10.4269/ajtmh.20-0642 article EN other-oa American Journal of Tropical Medicine and Hygiene 2020-06-20

BackgroundThe burden of stroke among hypertensive and diabetic population in sub-Saharan Africa remains high. We sought to identify the risk factors associated with occurrence these high-risk groups.MethodsA prospective cohort study involving adults hypertension or type II diabetes mellitus at 5 public hospitals Ghana who were stroke-free enrollment. Patients followed every 2 months clinic for 18 assessed clinically first ever by physicians. calculated crude incidence rates using a...

10.1016/j.jns.2018.09.018 article EN cc-by Journal of the Neurological Sciences 2018-09-13

Introduction: Community health worker (CHW) interventions improve outcomes of patients from underserved communities, but professionals’ perceptions their effectiveness may impede integration CHWs into care delivery systems. Whether attitudes and skills, such as those related to cultural competence, influence CHWs, is unknown. Methods: A questionnaire was administered providers clinical staff 6 primary practices in Maryland April December 2011. We quantified the associations self-reported...

10.1177/2150131914540917 article EN Journal of Primary Care & Community Health 2014-07-01

Introduction The 10th outbreak of Ebola Virus Disease (EVD) in the Democratic Republic Congo (DRC) 2018–2020 was largest DRC’s history and second worldwide. Different strategic response plans (SRPs) were implemented, eventually stopped after a large scale-up operations with SRP 4, which benefited from all public health measures deployed during SRPs 1-3, upon it developed more holistic approach including community engagement, logistics security. Methods We used modelling to characterise EVD...

10.1136/bmjgh-2024-015822 article EN cc-by-nc-nd BMJ Global Health 2025-04-01

The burden of uncontrolled type-2 diabetes (T2DM) sub-Saharan Africa is high, with an increased risk developing microvascular and macrovascular complications. We sought to identify predictors poor control among Ghanaians T2DM. A cross-sectional study involving 1226 participants T2DM enrolled at five health facilities in Ghana (2 tertiary, 2 district 1 rural hospital). Data on demographics, medical history, lifestyle factors, anti-diabetic medications, treatment adherence were collected....

10.1016/j.tmsr.2018.09.001 article EN cc-by Translational Metabolic Syndrome Research 2018-09-11

Genetic polymorphisms in Plasmodium falciparum are associated with resistance to a number of drugs, but data on their prevalence limited from many areas. We explored the key patients presenting malaria Kinshasa. Prevalences pfcrt K76T; pfmdr1 N86Y; pfdhfr N51I, C59R, and S108N; pfdhps A437G were well above 50% Y184F, N1042D, D1246Y; I164L; K540E low. These results suggest an intermediate level aminoquinoline antifolate antimalarials Kinshasa compared other areas Africa.

10.4269/ajtmh.2009.80.555 article EN American Journal of Tropical Medicine and Hygiene 2009-04-01

Sub-Saharan Africa is currently experiencing a high burden of both chronic kidney disease (CKD) and stroke as result rapid rise in shared common vascular risk factors such hypertension diabetes mellitus. However, no previous study has prospectively explored independent associations between CKD incident occurrence among indigenous Africans. This sought to fill this knowledge gap.A prospective cohort involving Ghanaians adults with or type II mellitus from 5 public hospitals. Patients were...

10.1016/j.jns.2018.11.017 article EN cc-by Journal of the Neurological Sciences 2018-11-15

Abstract There are limited data on factors associated with longitudinal control of blood pressure (BP) among Ghanaians antihypertensive treatment. We sought to evaluate associations between prospective BP and 24 putative within socio‐demographic, biological, organizational domains. This is a cohort study involving 1867 (65%) adults hypertension 1006 (35%) both diabetes mellitus at five public hospitals. Clinic was measured every 2 months for 18 follow‐up. A multivariate logistic regression...

10.1111/jch.13873 article EN Journal of Clinical Hypertension 2020-04-30

<ns5:p>The coronavirus disease 2019 (COVID-19) pandemic has exacerbated health disparities across ethnic and socioeconomic groups. Non-communicable diseases (NCDs) - such as hypertension, diabetes, obstructive lung – are key drivers of this widening gap, because they disproportionately afflict vulnerable populations.</ns5:p><ns5:p> Vulnerable populations with non-communicable diseases, in turn, affected by COVID-19 itself but also at increased risk poor outcomes from those underlying...

10.12688/gatesopenres.13181.1 preprint EN cc-by Gates Open Research 2020-09-09

<ns4:p><ns4:bold>Background:</ns4:bold> There is evidence to suggest that the prevalence of non-communicable diseases (NCDs), in particular cardiovascular and diabetes, are being recognized as forming a substantial proportion burden disease among populations Low- Middle-Income Countries (LMICs). Access treatment likely key barrier control prevention NCD outcomes. Differential pricing, an approach used price drugs based on purchasing power patients different socioeconomic segments, has been...

10.12688/gatesopenres.12797.1 preprint EN cc-by Gates Open Research 2018-02-07

<ns4:p><ns4:bold>Background:</ns4:bold> There is evidence to suggest that the prevalence of non-communicable diseases (NCDs), in particular cardiovascular and diabetes, are being recognized as forming a substantial proportion burden disease among populations Low- Middle-Income Countries (LMICs). Access treatment likely key barrier control prevention NCD outcomes. Differential pricing, an approach used price drugs based on purchasing power patients different socioeconomic segments, has been...

10.12688/gatesopenres.12797.2 preprint EN cc-by Gates Open Research 2018-05-03

Introduction: On November 8, 2013, Super Typhoon Haiyan struck the Philippines, causing a humanitarian emergency.According to World Health Organization, non-communicable diseases (NCDs), also known as chronic diseases, are leading cause of death and disability around world.NCDs kill 38 million people each year.Sixteen NCD deaths occur before age 70; 82% which occurred in low-and middle-income countries.NCDs further exacerbated during crisis, addressing them should be concern any medical...

10.1371/currents.dis.5aaeb105e840c72370e8e688835882ce article EN PLoS Currents 2016-01-01

Although the high case fatality rate (CFR) associated with Ebola virus disease (EVD) is well documented, there are limited data on actual modes of death. We conducted a retrospective, observational cohort study among patients laboratory-confirmed EVD. The were all seen at Eternal Love Winning Africa Treatment Unit in Monrovia, Liberia, from June to August 2014. Our primary objective was describe death our and determine predictors mortality. Data available for 53 EVD, median age 35 years....

10.4269/ajtmh.17-0090 article EN cc-by American Journal of Tropical Medicine and Hygiene 2018-02-06

The 2014–2016 Ebola virus disease (EVD) outbreak in West Africa was of unprecedented magnitude with a total 28,616 suspected, probable, and confirmed cases reported Guinea, Liberia, Sierra Leone. international humanitarian community utilized its expertise rapid response scale up emergency situations to manage threat different from the more common emergencies resulting conflict or natural disaster. Unique multisectoral partnerships forged between traditional public health actors facilitated...

10.1186/s41018-018-0039-2 article EN cc-by Journal of International Humanitarian Action 2018-06-27

aS ince the onset of Ebola outbreak in West Africa February 2014, World Health Organization estimates that more than 370 health care workers have been infected with virus disease (EVD), and 216 since died. 1 During height epidemic, I had unique opportunity working at Case Management Center Eternal Love Winning (ELWA) hospital Monrovia, Liberia.About a third all patients admitted to ELWA were workers. 2 Some these brave individuals worked tirelessly, treating while fully aware they could...

10.9745/ghsp-d-14-00157 article EN cc-by Global Health Science and Practice 2014-10-13

With increasing population displacement and worsening water insecurity after the 2010 earthquake, Haiti experienced a large cholera outbreak. Our goal was to evaluate strengths weaknesses of seven community health facilities’ ability respond surge in cases.Since 2010, Catholic Relief Services (CRS) with number public private donors has been working facilities an effort reduce morbidity mortality from infection. In November 2012, CRS through Centers for Disease Control Prevention (CDC)’s...

10.5055/ajdm.2013.0129 article EN American Journal of Disaster Medicine 2013-09-01

<ns4:p>The global burden of non-communicable diseases (NCDs) is growing, and access to prevention treatment strategies remain limited, especially for those in low- middle-income countries (LMICs).</ns4:p><ns4:p> Novel approaches are needed improve affordability medicines that can treat NCDs LMICs. The Access Affordability Initiative (AAI) a public private partnership aiming availability essential the strengthening health systems. Through this novel initiative prospective cohort patients with...

10.12688/gatesopenres.12798.2 preprint EN cc-by Gates Open Research 2019-12-24

<ns4:p><ns4:bold>Background:</ns4:bold> Access to medicines for hypertension and diabetes mellitus (DM) management is challenging in resource-limited countries. We sought assess whether differential pricing of based on socio-economic status would improve affordability antihypertensive anti-diabetic medications. A quasi-experimental, prospective cohort study was implemented at five Ghanaian health facilities, using differentially priced by three pharmaceutical companies.</ns4:p><ns4:p>...

10.12688/gatesopenres.13044.1 preprint EN cc-by Gates Open Research 2019-08-07

"When Potentially Lifesaving Drugs are Both Experimental and in Very Short Supply: A Clinician's Story from the Front Lines of Battle Against Ebola" published on 05 Aug 2015 by The American Society Tropical Medicine Hygiene.

10.4269/ajtmh.15-0302 article EN American Journal of Tropical Medicine and Hygiene 2015-06-02
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