A5100639196- Food Quality and Safety Studies
- Meat and Animal Product Quality
- Probiotics and Fermented Foods
- Listeria monocytogenes in Food Safety
- Nutrition, Health and Food Behavior
- Food Safety and Hygiene
- Natural product bioactivities and synthesis
- Microbial Inactivation Methods
- Education and Learning Interventions
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- Healthcare Education and Workforce Issues
- Gut microbiota and health
- Health and Wellbeing Research
- Protein Hydrolysis and Bioactive Peptides
- Identification and Quantification in Food
- Salmonella and Campylobacter epidemiology
- MicroRNA in disease regulation
- Genomics, phytochemicals, and oxidative stress
- Fibroblast Growth Factor Research
- Glutathione Transferases and Polymorphisms
- Metal-Organic Frameworks: Synthesis and Applications
- Muscle Physiology and Disorders
- Extracellular vesicles in disease
- Diverse Scientific Research Studies
Kangwon National University
2017-2025
Seoul National University
2024
Yeungnam University
2020-2023
Chungbuk National University
2007-2023
Konkuk University
2009-2016
National Veterinary Research and Quarantine Service
2009-2011
Korea Fisheries Resources Agency
2010
United States Food and Drug Administration
2005
University of Bonn
2004
Structures of the human lysosomal K + channel transmembrane protein 175 (TMEM175) in open and closed states revealed a novel architecture lacking canonical selectivity filter motif present previously known structures. A hydrophobic constriction composed four isoleucine residues was resolved pore proposed to serve as gate state, confer ion state. Here, we achieve higher-resolution structures employ molecular dynamics simulations analyze conducting properties putative demonstrating that it is...
Abstract Background Acute lung injury (ALI), including its most severe form, acute respiratory distress syndrome (ARDS), is a common cause of hypoxemic failure. Although clinical characteristics have been well characterized, the relevant mechanism remains unclear. An imbalance in autophagy leads to alveolar remodeling and triggers pathogenesis ARDS. In this study, we assessed therapeutic efficacy STAT1 inhibitor fludarabine (Fluda) ALI. C57BL6 mice were exposed lipopolysaccharide (LPS),...
Abstract Zr‐based metal–organic frameworks (MOFs) were modified with pendant tetrazole ligands for proton conductivity studies. Although tetrazolate coordinated to metal cations have been widely utilized construct MOFs or porous coordination polymers, date, the use of uncoordinated groups in has limited. In this study, a benzene‐1,4‐dicarboxylic acid (BDC‐N 4 ) was synthesized and used prepare UiO‐66 MOF using mixed‐ligand strategy. The tetrazole‐functionalized UiO‐66‐N compared containing...
Obesity is a major risk factor for metabolic syndrome and serious health concern worldwide. Various strategies exist to treat prevent obesity, including dietary approaches using bioactive ingredients from natural sources.This study aimed investigate the anti-obesity effect of whole-plant Allium macrostemon (also called as long-stamen chive) extract (AME) potential new functional food.C57BL/6N mice were divided into three groups fed either control diet (CD), high-fat (HFD), or HFD with AME...
The purpose of this study is to investigate the effect Agrimonia pilosa Ledeb. extract (APLE) on lipopolysaccharide‐ (LPS‐) induced cell damage in hepatocytes with a focus antioxidant and anti‐inflammatory activities. Total activities APLE itself were analyzed phytochemical analysis was performed. Moreover, inhibitory effects LPS‐induced oxidative stress inflammation assessed human HepG2 hepatocytes. found exert α , ‐diphenyl‐ β ‐picrylhydrazyl (DPPH),...
A rapid and specific PCR assay for the simultaneous detection of Listeria monocytogenes, Escherichia coli O157:H7, Bacillus cereus, Salmonella spp., Staphylococcus aureus in foods was developed to reduce time increase sensitivity. Multiplex this study produced only actA, fliC, hbl, invA, ileS amplicons, but did not produce any non-specific amplicon. The primer sets successfully amplified target genes multiplex without or additional bands on other strains. assays also some from five...
Sarcopenia is a progressive muscle disease characterized by the loss of skeletal mass, strength, function, and physical performance. Since code was assigned, attention has been focused on natural products that can protect against atrophy. Cibotium barometz (Cibotium Rhizome) used as an herbal medicine for treatment bone or joint diseases in Asian countries. However, no studies have identified mechanism action Rhizome atrophy related to sarcopenia at site myotubes. The aim this study...
본 연구는 65세 이상의 노인을 대상으로 만성통증과 사회적지지가 노인의 우울과 자살의도에 미치는 영향을 파악하고자 연구되었다. 연구대상은 복지관을 이용하는 만성통증이 있는 자료수집기간은 2014년 4월 20일부터 5월 20일까지 시행하였고, 최종 178부를 자료를 분석하였다. 수집된 자료는 SPSS를 이용하여 실수와 백분율, 평균과 표준편차, t-test, ANOA, 상관관계, 다중회귀분석을 하였다. 연구분석 결과 만성통증은 유의한 정적 상관관계가 나타났으며 사회적지지는 부적 나타났다. 또한, 미치며 우울에 영향 가장 강력한 변수로 확인되었다. 있어서 높을수록 자살의도는 높아지고 낮을수록 자살의도가 높아지는 결과를 나타냈다. 따라서 자살을 예방하기 위해 가족과 사회적 관심과 사회적지지 서비스 개발이 필요하며만성통증을 경감시켜 줄 수 다양한 프로그램 개발과 중재가 필요하다. This research is aged 65 or older with chronic pain and...