A5004449717- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Health and Disease Prevention
- Cancer-related molecular mechanisms research
- Peripheral Artery Disease Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Technology Adoption and User Behaviour
- Ferroptosis and cancer prognosis
- Digital Marketing and Social Media
- Gallbladder and Bile Duct Disorders
- RNA modifications and cancer
- Advanced Computational Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Bladder and Urothelial Cancer Treatments
- Heat Transfer and Boiling Studies
- Spinal Fractures and Fixation Techniques
- Pancreatic and Hepatic Oncology Research
- Neurofibromatosis and Schwannoma Cases
- Radiomics and Machine Learning in Medical Imaging
- Circular RNAs in diseases
Capital Medical University
2018-2025
University of Virginia
2025
Sarasota Memorial Hospital
2025
Xi'an Jiaotong University
2025
First People's Hospital of Yunnan Province
2025
Kunming University of Science and Technology
2025
Beijing Microelectronics Technology Institute
2023-2024
Cardiff University
2024
Central South University
2010-2024
Beijing Friendship Hospital
2024
Purpose – With recent advances in internet technologies, of things (IoT) technology is having an increasing impact on our daily lives, and beginning to offer interesting advantageous new services. The current research aims develop test integrative model factors determining consumers' acceptance IoT technology. Design/methodology/approach Based (TAM), the authors proposed that consists three (perceived usefulness, perceived ease use, trust); one social context factor (social influence); two...
Purpose – Users' continuance intention is vital to the future of mobile social networking service (SNS) with rapid development and intensive competitions among its providers. The purpose this research identify factors affecting SNS users' intention. Design/methodology/approach Data from an online survey administered 228 users are used test model through use structural equation modelling. Findings results show that flow, perceived usefulness satisfaction determine SNS. Moreover, authors found...
Cerebral ischemia-reperfusion (I/R) injury is a major cause of early complications and unfavorable outcomes after endovascular thrombectomy (EVT) therapy in patients with acute ischemic stroke (AIS). Recent studies indicate that modulating microglia/macrophage polarization subsequent inflammatory response may be potential adjunct to recanalization. Annexin A1 (ANXA1) exerts potent anti-inflammatory pro-resolving properties models cerebral I/R injury. However, whether ANXA1 modulates...
Importance Prior trials of extracranial-intracranial (EC-IC) bypass surgery showed no benefit for stroke prevention in patients with atherosclerotic occlusion the internal carotid artery (ICA) or middle cerebral (MCA), but there have been subsequent improvements surgical techniques and patient selection. Objective To evaluate EC-IC symptomatic ICA MCA, using refined operator Design, Setting, Participants This was a randomized, open-label, outcome assessor–blinded trial conducted at 13...
Virtual travel communities (VTCs) are now popular and influential venues for tourism information sharing. With the increasing number of VTCs low switching cost, it is challenging to retain existing users encourage their continued participation. Despite importance user retention survival, little research attention has been devoted understanding members’ participation behavior. The purpose this study test a new model VTC beliefs, attitudes, continuance behaviors, by integrating system success...
BackgroundThere is a lack of comprehensive profile assessment on complete blood count (CBC)-derived systemic-inflammatory indices, and their correlations with clinical outcome in patients anterior circulation acute ischemic stroke (AIS) who achieved successful recanalization by endovascular thrombectomy (EVT).MethodsPatients AIS caused large vessel occlusion (AIS-LVO) were retrospectively screened from December 2018 to 2022. Systemic-inflammatory indices including ratios...
Rationale: The Chemical Optimization of Cerebral Embolectomy (CHOICE) trial suggested that the administration intra-arterial alteplase after successful endovascular thrombectomy (EVT) may improve neurological outcomes in patients with acute ischemic stroke due to large vessel occlusion (AIS-LVO) anterior circulation. However, use adjunctive following EVT posterior circulation remains unexplored. Aims: This study aims investigate efficacy and safety for AIS-LVO Sample Size: To detect an...
Abstract A malformed tumour vascular network provokes the nutrient‐deprived microenvironment (TME), which conversely activates endothelial cell (EC) functions and stimulates neovascularization. Emerging evidence suggests that flexible metabolic adaptability of cells helps to establish a symbiosis among various subpopulations in fluctuating TME. In this study, authors propose novel link between bladder cancer (BCa) ECs nutrient‐scarce TME, BCa‐secreted glutamine‐fructose‐6‐phosphate...
Endothelial dysfunction is a key proponent of pathophysiological process traumatic brain injury (TBI). We previously demonstrated that extracellular vesicles (EVs) released from injured brains led to endothelial barrier disruption and vascular leakage. However, the molecular mechanisms this EV-induced (endotheliopathy) remain unclear. Here, we enriched plasma EVs TBI patients (TEVs), detected high mobility group box 1 (HMGB1) exposure 50.33 ± 10.17% TEVs number HMGB1+TEVs correlated with...
Current techniques of knowledge management have some common defects in efficiency, scalability, and applicability. Knowledge graph provides a new way for is more flexible method. Considering the specific features crop diseases pest data, this paper analyzed classified key methods technology field recent years. We introduced definition connotation knowledge, current construction method it was detail from four aspects: representation, extraction, fusion, reasoning. Furthermore, application...
Abstract This article aims to examine the influence of green strategic alliances (GSA) on both radical and incremental innovation through effects supply chain integration (GSCI). A theoretical model was proposed evaluated using structural equation modeling. 37‐item questionnaire created assess relationships, a total 303 valid responses were obtained from sample industrial service companies in China. The findings indicate that GSA have positive impact GSCI, thus, innovation. study also...
Changes in matrix metalloproteinase (MMP)-2, MMP-9, inflammation, blood coagulation factors and intestinal mucosal permeability patients with active ulcerative colitis (UC) were investigated. A total of 50 UC treated our hospital from January 2016 to December 2018 selected as the group, whereas normal subjects receiving physical examination control group. Venous was drawn detect content early predictors, C‑reactive protein (CRP), follistatin‑like 1 (FSTL1) D‑dimer serum. The disease activity...
Globally, hepatocellular carcinoma (HCC) is one of the most common causes cancer-associated mortalities. It has a high rate metastasis and recurrence, which predict poor prognosis. G-protein-coupled receptor (GPCR)-kinase interacting protein-1 (GIT1) multifunctional scaffold protein that mediates progression various tumors. Studies have correlated GIT1 with HCC, however, these correlations not been fully elucidated. Therefore, we aimed at evaluating expression in HCC tissues cells, to...
Abstract Objective To develop a computed tomography (CT) radiomics-based interpretable machine learning (ML) model to preoperatively predict human epidermal growth factor receptor 2 (HER2) status in bladder cancer (BCa) with multicenter validation. Methods In this retrospective study, 207 patients pathologically confirmed BCa were enrolled and divided into the training set ( n = 154) test 53). Least absolute shrinkage selection operator (LASSO) regression was used identify most...
This study investigated the role of integrin-linked kinase (ILK) in neuronal apoptosis induced by cerebral ischemia‒reperfusion injury (CIRI) and its interaction with a circRNA (0000964) miR-758-3p. Using vivo vitro rat models, we clarified how ILK regulates during CIRI. Our findings revealed that expression is upregulated response to CIRI modulated (0000964)/miR-758-3p axis. provides new insights into molecular mechanisms suggests potential therapeutic targets reduce apoptosis. A model was...
<h3>ABSTRACT</h3> <h3>BACKGROUND AND PURPOSE:</h3> This study explores the impact of stenosis degree on outcomes stenting compared with medical therapy alone in patients symptomatic intracranial artery stenosis. <h3>MATERIALS METHODS:</h3> Patients a transient ischemic attack or nondisabling stroke, attributed to 70 99% major artery, were included. The patient cohort was drawn from China Angioplasty and Stenting for Symptomatic Intracranial Severe Stenosis (CASSISS) Aggressive Medical...