- Cancer-related molecular mechanisms research
- Nerve Injury and Rehabilitation
- Peripheral Nerve Disorders
- Nerve injury and regeneration
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Heavy metals in environment
- Radiomics and Machine Learning in Medical Imaging
- Acute Kidney Injury Research
- RNA modifications and cancer
- Anesthesia and Neurotoxicity Research
- Healthcare and Venom Research
- Cancer, Hypoxia, and Metabolism
- Lung Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Orthopedic Surgery and Rehabilitation
- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- Cancer, Lipids, and Metabolism
- Electrolyte and hormonal disorders
- Spinal Cord Injury Research
- Venomous Animal Envenomation and Studies
- Cancer-related gene regulation
- Selenium in Biological Systems
Chinese PLA General Hospital
2015-2025
Fudan University
2014-2025
Shanghai Stomatological Hospital
2023-2025
Tongji University
2023-2025
Kunming Medical University
2017-2025
Huashan Hospital
2012-2025
China Agricultural University
2025
Ministry of Agriculture and Rural Affairs
2023-2025
TEDA International Cardiovascular Hospital
2015-2025
Tianjin Medical University
2023-2025
Whole-genome sequencing of 25 metastatic melanomas and matched germline DNA in humans reveals that the highest mutation load is associated with chronic sun exposure, PREX2 gene mutated approximately 14 per cent cases Melanoma a highly cancer, characterized by high lethality rapid development resistance to treatment. rate varies widely, exposure sunlight. — PTEN-interacting protein previously implicated breast cancer 14% cases. Although precise role melanoma remains be elucidated, ectopic...
Abstract Severe COVID-19 disease caused by SARS-CoV-2 is frequently accompanied dysfunction of the lungs and extrapulmonary organs. However, organotropism port virus entry for systemic dissemination remain largely unknown. We profiled 26 autopsy cases from four cohorts in Wuhan, China, determined distribution SARS-CoV-2. was detected multiple organs critically ill patients up to 67 days after symptom onset. Based on pathological features patients, divided into viral intrapulmonary subtypes....
Osteosarcoma is the most common malignant tumor of bone. Recent studies have proven long non-coding RNAs (lncRNAs) play important roles in tumorigenesis and progression cancer. However, few lncRNAs been investigated osteosarcoma. Here, we reported a novel lncRNA, suppressor candidate 7 (TUSC7), was significantly downregulated osteosarcoma tissues compared with paired non-tumor low expression TUSC7 indicated poor survival (HR = 0.313, 95 % confidence interval (CI) 0.092–0.867) patients....
Abstract This study was to develop a radiomics nomogram mainly using wavelet features for identifying malignant and benign early-stage lung nodules high-risk screening. A total of 116 patients with solitary pulmonary (SPNs) (≤ 3 cm) were divided into training set (N = 70) validation 46). Radiomics extracted from plain LDCT images each patient. signature then constructed the LASSO set. Combined independent risk factors, built multivariate logistic regression model. signature, consisting one...
Objective The purpose of this study was to assess the correlation between metabolic score for insulin resistance (METS-IR) index and gallbladder stoneprevalence in US adults, as well age at first stone surgery. Methods A logistic regression analysis, subgroup dose-response curve were computed participants 2017-2018 National Health Nutrition Examination Survey (NHANES) relationship METS-IR prevalence surgery stones. Results This ultimately included 9452 aged >20 years, whom 534...
Periodontitis is intimately associated with the development of various systemic diseases, among which type 2 diabetes mellitus (T2DM) has a bidirectional relationship pathogenesis periodontitis. The objective present work was to investigate role berberine (BBR) in periodontitis T2DM and related mechanisms.
This study was conducted to observe the characteristics of risk factors carpal tunnel syndrome (CTS) in Chinese population. CTS 1,512 outpatients aged 41-70 years were without any other diseases which could cause numbness as a case group, and 4,536 non-CTS control group involved 2013-2014. Both groups received questionnaire another electrical physiological examination. The results showed odds ratio (OR) age is 0.990 (95% CI, 0.984-0.996). OR BMI 1.096 1.077-1.115). smoking 4.862...
This experiment was carried out to investigate the mechanism of action mulberry leaf extract (MLE) in reducing abdominal fat accumulation female broilers. A total 192 one-day-old Arbor Acres (AA) broilers were divided into 4 diet groups, with each group consisting 8 replicates 6 birds per replicate. The diets contained a basal and 3 test supplementation 400, 800, or 1,200 MLE mg/kg, respectively. trial had 2 phases that lasted from 1 21 d 22 56 d, growth performance, deposition, fatty acid...
An increasing body of evidence suggests that ribosomal proteins may have ribosome-independent functions and be involved in various physiological pathological processes. To examine the role protein L34 (RPL34) cancer transformation, we assessed its expression gastric cell lines found it highly expressed. We further used lentivirus-mediated small interfering RNAs (siRNAs) to knockdown RPL34 human line SGC-7901. RNA interference (RNAi)-mediated inhibition SGC-7901 cells significantly suppressed...