- Salmonella and Campylobacter epidemiology
- Antibiotic Resistance in Bacteria
- Food Safety and Hygiene
- Identification and Quantification in Food
- Vibrio bacteria research studies
- Aquaculture disease management and microbiota
- Listeria monocytogenes in Food Safety
- Pharmaceutical and Antibiotic Environmental Impacts
- Viral gastroenteritis research and epidemiology
- Neonatal and Maternal Infections
- Bacterial biofilms and quorum sensing
- Escherichia coli research studies
- Biosensors and Analytical Detection
- Meat and Animal Product Quality
- Sentiment Analysis and Opinion Mining
- Infection Control and Ventilation
- Antimicrobial Resistance in Staphylococcus
- Consumer Attitudes and Food Labeling
- Irrigation Practices and Water Management
- Conservation, Biodiversity, and Resource Management
- Nutritional Studies and Diet
- Oral microbiology and periodontitis research
- Probiotics and Fermented Foods
- Effects and risks of endocrine disrupting chemicals
- Rice Cultivation and Yield Improvement
National University of Singapore
2017-2025
Nanyang Technological University
2017-2025
Clinical Nutrition Research Centre
2023-2024
Myanmar Oxford Clinical Research Unit
2022-2023
Agri-Food and Veterinary Authority of Singapore
2017-2023
National Environment Agency
2015-2022
Livestock Breeding and Veterinary Department
2021
Singapore General Hospital
2017
Genome Institute of Singapore
2017
Recent research has highlighted the conflict potential of both land deals and climate change mitigation projects, but generally two phenomena are studied separately focus is limited to discrete cases displacement or contested claims. We argue that with a broader "landscape" perspective needed better understand complex social, ecological institutional interactions taking place in sites land-based projects (such as biofuel production forest conservation) large-scale investments (plantations...
There is a need to study the characteristics of outbreaks via Singapore's outbreak surveillance system understand and identify gaps in food safety for targeted policy interventions due increasing trend gastroenteritis consequential increase foodborne-related deaths economic burden on public health systems worldwide. A total 171 were investigated Singapore from January 2018 December 2021. This analyzed annual outbreaks, proportion by implicated sources food, type pathogens identified human...
Antimicrobial resistance (AMR) in Escherichia coli (E. coli) poses a public health concern worldwide. Wild birds and rodents, due to their mobility, are potential vehicles for transmission of AMR bacteria humans. Ninety-six wild birds’ faecal samples 135 rodents’ droppings were collected analysed 2017. Forty-six E. isolates from rodents subjected phenotypic genotypic characterisation. The proportion resistant at least one the antimicrobials tested (80.8%) was significantly higher than that...
As the preparation of salads involves extensive handling and use uncooked ingredients, they are particularly vulnerable to microbial contamination. This study aimed determine safety quality pre-packed salad bar ingredients sold in Singapore, so as identify public health risks that could arise from consuming areas for improvement management food safety. The most frequently encountered organism samples was B. cereus, pasta (33.3%, 10/30). commonly detected L. monocytogenes, particular seafood...
To determine the prevalence and genetic characteristics of ESBL-producing Escherichia coli in retail raw meats from Singapore markets.A total 634 meat (chicken, pork beef) samples were collected markets during June 2017-October 2018. The enriched overnight then incubated on Brilliance™ ESBL Agar. Presumptive isolates confirmed using double-disc synergy test. Confirmed E. sent for WGS bioinformatic analysis was performed.The chicken, beef 51.2% (109/213), 26.9% (58/216) 7.3% (15/205),...
Salmonella Enteritidis is a major foodborne pathogen worldwide. In this study, total of 276 S. enteritidis isolates, collected between 2016 and 2017 from human, food farm/slaughterhouse samples, were studied to enhance the understanding epidemiology human salmonellosis in Singapore. Results showed all isolates belonged either ST1925 (70.3%) or ST11 (29.7%), with being significantly more frequent extra-intestinal chicken isolates. Food most which poultry, highest prevalence resistance...
This study investigated the influence of 'snackification' in Singaporean diets, leading to increased dietary acrylamide exposure. Acrylamide concentrations commonly consumed foods within and outside main meals were measured using liquid chromatography with tandem mass spectrometry (LC-MS/MS). High detected vegetables cooked at high temperatures (ranging from 0.5 478.4 µg/kg) potato-based crackers chips 81.8 2095.8 µg/kg). The estimated total exposure for Singapore population was 0.165 µg/kg...
Abstract Background Escherichia coli sequence type 131 (E. ST131) is a global pandemic clone associated with the rapid dissemination of CTX-M–class extended spectrum β-lactamase (ESBL) genes, conferring resistance to several antibiotic classes, and major cause both healthcare community-acquired extraintestinal pathogenic E. (ExPEC) infections. The drivers ST131 pandemicity are not well-understood. Figure 1. Prospective cohort study enrollment flowchart Methods Between February 2017 November...
The tilapia (Oreochromis) aquaculture industry in Malaysia has expanded rapidly to meet the increasing demand for animal protein. However, this growth is challenged by microbial infections, particularly those caused emerging pathogen Aeromonas dhakensis. This study aimed investigate community composition across four distinct farming systems and assess associated water physicochemical parameters, with a focus on detecting presence of A. dhakensis elucidating its environmental associations....
Abstract We assessed microbial safety and quality of raw fish sold in Singapore during 2015–2016 to complement epidemiologic findings for an outbreak infection with group B Streptococcus serotype III sequence type (ST) 283 associated consumption. Fish-associated ST283 strains included nearly identical (0–2 single-nucleotide polymorphisms) the human strain, as well another distinct clade (57–71 polymorphisms). Our investigations highlight risk contamination freshwater (which are handled...
is ubiquitous in aquatic habitats and can cause life-threatening septicaemia humans. However, limited data are available on their antimicrobial susceptibility testing (AST) profiles. Hence, we aimed to examine AST patterns using clinical (
Staphylococcus aureus contamination of food and contact surfaces is a public health concern given its virulent antimicrobial-resistant properties worldwide. In this study, total 181 MSSA isolates were analyzed for SE genes, antimicrobial resistance patterns, spa types. Overall, 24.9% positive gene detection, with sea being the most prevalent classical (18.8%). The predominant sample sources hand swabs (6/48), meat dishes seb (3/14) seafood sec (2/24). Antimicrobial was also observed at...
Singapore's diarrhoeal notification system is based on specific pathogens. Official data may thus be skewed towards notifiable diseases. Limited information available the profiles of aetiological agents responsible for acute gastroenteritis (AGE) cases, especially among adult population. To understand frequency and distribution potential causative diarrheal disease in Singapore, we screened adults' stool samples collected from a large public hospital. The were 18 diarrheagenic pathogens...
We analyzed the epidemiological distribution of Salmonella serovars in humans, foods, animals and environment as a One-Health step towards identifying risk factors for human salmonellosis. Throughout 2012-2016 period, ser. Enteritidis was consistently predominating serovar attributing to >20.0% isolates humans. Other most common humans include Stanley, Weltevreden, Typhimurium 4,5,12:b:-(dT+). S. also frequent found among from chicken/chicken products (28.5%) eggs/egg (61.5%) during same...
This study investigated the prevalence and occurrence of 3-monochloropropanediol esters (3-MCPDEs) glycidyl (GEs) in domestically commercially prepared food Singapore assessed total dietary exposure for Singaporean population. Minimal impact on formation 3-MCPDEs GEs was observed from domestic cooking methods commonly practiced such as deep frying stir frying. The estimated to population (aged 15 92) 0.982 µg/kg bw/day general consumers 2.212 high (95th percentile), which accounted 49.1%...
We characterised 227 Staphylococcus aureus isolates from retail food and handlers' gloves samples obtained through surveillance risk assessment studies between 2011 2014. Of isolates, five (2.2%) were methicillin-resistant belonged to sequence types ST80 (n = 3) ST6 2). All SCCmec type IV, Panton-Valentine leukocidin (pvl)-negative staphylococcal enterotoxin genes-positive. Resistance azithromycin was found in addition resistance beta-lactams. Our finding of two clinically relevant S. (MRSA)...
Non-typhoidal salmonellosis is a leading cause of foodborne zoonosis. To better understand the epidemiology human salmonellosis, this study aimed to determine prevalence, antimicrobial resistance and sequence types Salmonella in retail food wild birds (proximity humans) Singapore. We analyzed 21,428 cooked ready-to-eat 1,510 residual faecal samples collected during 2010–2015. Thirty-two isolates from were subjected disc diffusion multi-locus typing (MLST). was isolated 0.08% (17/21,428)...