A5101008981- Polymer composites and self-healing
- Advanced Polymer Synthesis and Characterization
- Hydrogels: synthesis, properties, applications
- Silicone and Siloxane Chemistry
- Conducting polymers and applications
- Polymer Surface Interaction Studies
- Photochromic and Fluorescence Chemistry
- Marine Sponges and Natural Products
- Nanoparticle-Based Drug Delivery
- Advanced Materials and Mechanics
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Sensor and Energy Harvesting Materials
- Supramolecular Self-Assembly in Materials
- Surface Modification and Superhydrophobicity
- Polyoxometalates: Synthesis and Applications
- Synthesis and properties of polymers
- Nanomaterials for catalytic reactions
- biodegradable polymer synthesis and properties
- Micro and Nano Robotics
- Supramolecular Chemistry and Complexes
- Photopolymerization techniques and applications
- Surfactants and Colloidal Systems
- Marine Biology and Environmental Chemistry
- Photoreceptor and optogenetics research
- Electrochemical sensors and biosensors
Air Force Medical University
2011-2025
Xijing Hospital
2020-2025
Chengdu Organic Chemicals (China)
2013-2024
Chinese Academy of Sciences
2013-2024
University of Chinese Academy of Sciences
2015-2024
Southern Medical University
2024
Nanfang Hospital
2024
Wuhan Institute of Technology
2024
Tongji University
2024
Shenzhen Institutes of Advanced Technology
2021
Multiple-shape memory effects (SME) from dual to quintuple are realized in PMMA/PEG semi-interpenetrating polymer networks containing broadened glass transition and crystalline segments, which provide multi-gradient temperatures an additional melting temperature as for multi-step shape fixation recovery a single cycle. Especially, the quintuple-SME is achieved polymeric material first time.
Abstract Degradable shape memory polymers (SMPs), especially for polyurethane‐based SMPs, have shown great potential biomedical applications. How to reasonably fabricate SMPs with the ideal combination of degradability, reconfigurability, and reprocessability is a critical issue remains challenge medical disposable materials. Herein, poly(urethane‐urea) synergetic triple dynamic covalent bonds reported via embedding polycaprolactone unit into hindered urea bond. The single polymer network...
Because of a large difference in storage modulus below and above the glass transition temperature, poly(acrylic acid-co-methyl methacrylate)/poly(ethylene glycol) (P(AA-co-MMA)/PEG) complexes show shape memory properties with recovery ratio nearly reach 99%. Before testing, it was necessary to determine conformational changes P(AA-co-MMA) gel induced by complexation linear PEG. It found that both concentration molecular weight PEG have strong effect on gel. In such system minimum required...
Abstract Summary: A well‐dispersed gold nanoparticle/poly( N ‐isopropylacrylamide) (PNIPAm) hydrogel nanocomposite with thermoswitchable electrical properties is prepared by the copolymerization of functional Au nanoparticles ‐isopropylacrylamide. It found that conductivity changes two orders magnitude at moderate temperature ( T tran ) upon stimuli. The change reversible during a heating and cooling cycle. Schematic illustration mechanism thermo‐switchable electronic nanoparticle/PNIPAm...
In this paper, polymer nanocapsules embedded with noble metal nanoparticles and showing a good catalytic activity were prepared by novel convenient method.
Abstract Summary: This communication describes a novel kind of PMMA‐PEG semi‐interpenetrating network (semi‐IPN) which shows excellent shape‐memory behavior at two transition temperatures, the T m PEG crystal and g semi‐IPN. Based on reversible order‐disorder crystals below above PEG, large difference in storage modulus semi‐IPN, polymer has recovery ratio 91 99%, respectively. Shape‐memory phenomena PMMA‐PEG2000 magnified image
The water dispersion of poly-N-isopropylacrylamide hybrid nanoparticles exhibited temperature-triggered magnetic separation behaviour: if the temperature switched between below and above 32 °C, could be dispersed into reversibly separated by a field 1.1 T.
Abstract Summary: Magnetic nanoparticles have been prepared by a co‐precipitation method and modified with methacryloxypropyltrimethoxysilane. molecularly imprinted polymer particles suspension polymerization in silicone oil. The possess high affinity to the template molecules are rapidly separated under magnetic field. SEM photograph of MIP particles. magnified image
Rheumatoid arthritis (RA) is an inflammatory and angiogenic disease. However, the molecular mechanisms that promote angiogenesis in RA have not been clearly identified. Our objective was to study role of CD147 determine whether strategy which suppressed might be useful reducing RA.Correlations among expression levels CD147, vascular endothelial growth factor (VEGF), hypoxia-inducible 1α (HIF-1α) were determined by immunohistochemistry staining. fibroblast-like synoviocytes (FLS) cells...
Thermosensitive cross-linked polymer vesicles were formed by self-assembly of block copolymer poly(2-cinnamoylethyl methacrylate)-block-poly(N-isopropylacrylamide) (PCEMA61-b-PNIPAM22) and subsequent photo-cross-linking PCEMA shells. The ability these to load release 4-aminopyridine (Apy), a model compound, is discussed. It found that the can large amount Apy compound at tunable rate depending on temperature. also show satisfactory reversible reproducible thermosensitive characteristics.
Abstract A simple efficient post‐modification route to the fabrication of hybrid gold nanoparticles with poly( N ‐isopropylacrylamide) (PNIPAm) based on click chemistry is described. The PNIPAm was prepared by reversible addition fragmentation chain transfer radical polymerization (RAFT). immobilized onto grafting densities 5.8 chains · nm −2 a reaction. showed temperature responsive phenomenon as changed between 20 and 45 °C. magnified image
Abstract Photoresponsive polymer with azobenzene pendant group (PDMAA‐ co ‐PAPA) was synthesized by radical polymerization of N , ‐dimethylacrylamide (DMAA) and ‐4‐phenylazophenyl acrylamide (PAPA), the characterization inclusion complexes PDMAA‐ ‐PAPA α‐cyclodextrin (α‐CD) were performed FTIR, GPC, 1 H NMR, 2D NOESY, UV–vis spectroscopy. It found that solubility α‐CD in aqueous solution showed tunable property, which could be triggered alternating light irradiation at a certain temperature...
Vascular restenosis is a serious clinical issue initiated and aggravated by macrophage inflammation, with no effective treatments available, in cardiovascular autoimmune diseases. However, the untapped mechanisms new targets that can regulate polarization vascular remain elusive. The research identifies interferon regulatory factor 4 (IRF4) expression as crucial during arterial restenosis. Myeloid-specific Irf4 deficiency overexpression experiments showed IRF4 promoted M2 polarization,...
Chronic obstructive pulmonary disease (COPD) is intricately linked to fibrosis, yet the underlying mechanisms remain unclear. This study investigates whether CH25H/25-hydroxycholesterol (25-HC) promotes fibrosis in COPD by modulating AMPK/STAT6-dependent M2 macrophage polarization. Using GEO datasets and a cigarette smoke-induced mouse model, we analyzed CH25H expression fibrotic pathology. was silenced via adeno-associated virus (AAV)-delivered shRNA. Histopathology, flow cytometry, qPCR,...
A well-dispersed gold nanoparticle–poly-N-isopropylacrylamide (PNIPAm) hydrogel composite with thermo-switchable electrical properties was prepared by the co-polymerization of Au nanoparticles attached vinyl groups NIPAm. The and are characterized TEM, UV-Vis, FTIR, NMR. At same time, conductivity, cyclic voltammetry constant-pontential technique were used to demonstrate composite. It found that show a tunable property changing temperature conductivity changes two orders magnitude at...
A novel route has been developed to prepared beta-cyclodextrin (beta-CD) functionalized magnetic nanoparticles (MNPs). The MNPs were first modified with monotosyl-poly(ethylene glycol) (PEG) silane and then tosyl units displaced by amino-beta-CD through the nucleophilic substitution reaction. monotosyl-PEG was synthesized modifying a PEG diol form corresponding monotosyl-PEG, followed reaction 3-isocyanatopropyltriethoxysilane (IPTS). success of synthesis confirmed (1)H NMR Fourier transform...
In a world where adaptive entities meet chemical oscillators, materials are in autonomic motion and assembly systems completely self-regulated! We review herein the key challenges new trends at interface of fields exhibit autonomous, reversible periodical variation without any external stimuli. Particular attention is paid to design philosophy recently reported actuators self-regulated systems.