- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- CCD and CMOS Imaging Sensors
- Advanced Biosensing Techniques and Applications
- Advanced Chemical Sensor Technologies
- RNA modifications and cancer
- SARS-CoV-2 detection and testing
- Receptor Mechanisms and Signaling
- Electrochemical sensors and biosensors
- Connexins and lens biology
- Botulinum Toxin and Related Neurological Disorders
- Photoreceptor and optogenetics research
- Genetics and Physical Performance
- Renin-Angiotensin System Studies
- Bioinformatics and Genomic Networks
- Machine Learning in Bioinformatics
- Carbon and Quantum Dots Applications
- Computational Drug Discovery Methods
- Retinal Development and Disorders
- Erythrocyte Function and Pathophysiology
- Advanced Nanomaterials in Catalysis
University of Agriculture Faisalabad
2021-2023
National Institute for Biotechnology and Genetic Engineering
2018-2022
Pakistan Institute of Engineering and Applied Sciences
2018-2022
International Islamic University, Islamabad
2012
Brazilian Institute of Geography and Statistics
2012
Paper-based microfluidics is the branch of involving devices made out paper, or other porous membranes, that wick fluids by capillary action. microfluidic have several advantages over conventional including simpler fabrication, lower cost, easier disposal, and ability to operate without pumps supporting equipment. The most common application paper-based in development point-of-care (POC) diagnostic devices, which could eliminate need for costly time-consuming laboratory-based analytical...
In resource-limited settings, the availability of medical practitioners and early diagnostic facilities are inadequate relative to population size disease burden. To address cost delayed time issues in diagnostics, strip-based immunoassays, e.g. dipstick, lateral flow assay (LFA) microfluidic paper-based analytical devices (microPADs), have emerged as promising alternatives conventional approaches. These assays rely on chromogenic agents detect biomarkers. However, limited specificity...
Background: Oculodentodigital syndrome (ODD; OMIM #164200) is a rare autosomal dominant disorder with pleiotropic effects.It caused by mutation in gap junction protein α 1 (GJA1) gene which encodes connexion 43.ODD characterised symptoms i.e. craniofacial, neurologic, limb, ocular abnormalities, syndactyly type III of the hands, phalangeal diffuse skeletal dysplasia, enamel and hypotrichosis.Objectives: To study Molecular Genetics syndrome.Patients/materials methods: Our current includes...
Motivation: Rhodopsin is a visual pigment present in rod cells of retina.It belongs to GPCR family and involves photoisomerization 11-cis-retinal all-trans-retinal isomers, conformational changes rhodopsin signal transduction cascade generate nerve impulse.This signaling pathway has been targeted eliminate the effect mutation (Gly90 Asp) responsible for abnormal activation G-protein without retinal conformations absence light leading congenital night blindness.A theoretical model with...
FrameQR ® code, microfluidic paper-based analytical devices (microPADs), point of care (POC), telehealth, alkaline phosphatase, ALP Microfluidic (microPADs) have significantly strengthened telehealth services by providing on-site disease biomarker screening, with the additional provision colorimetric output quantification image analysis applications.The analyte results can be stored or shared in a centralized database accessible to healthcare professionals for and e-prescription.However,...
In this era of rapidly evolving genetic and non-genetic diseases, in-silico analysis disease related proteins has proven beneficial in identification characterization potential therapeutic targets. present study, angiotensinogen (AGT) was studied for its sequence based ortholog paralogs, structural characterization, mutational analysis, protein interactions evolutionary changes. Sequence studies identified 194 orthologs 36 paralogs AGT. Functional AGT polymorphisms revealed the association...
Owing to unique physical and optical properties, fluorescent carbon dots (C-dots) are used in various biomedical applications. In this study, C-dots have been integrated as sensing agent on paper surface for colorimetric determination of clinically important analytes. Polyacrylamide-based coated C-dips showed visible color change from white brown iron (Fe2+, Fe3+) sample. Moreover, copper (Cu2+) samples significant quenching under UV. Images captured with/without UV were analyzed study the...