Jianxiu Wang

ORCID: 0000-0003-4328-4237
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Nanocluster Synthesis and Applications
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Advanced Nanomaterials in Catalysis
  • Biosensors and Analytical Detection
  • Electrochemical sensors and biosensors
  • Protein Interaction Studies and Fluorescence Analysis
  • Pharmaceutical and Antibiotic Environmental Impacts
  • RNA Interference and Gene Delivery
  • Nanoplatforms for cancer theranostics
  • DNA and Nucleic Acid Chemistry
  • Pharmacological Effects and Assays
  • Cellular transport and secretion
  • Sulfur Compounds in Biology
  • Lipid Membrane Structure and Behavior
  • Molecular Sensors and Ion Detection
  • Gas Sensing Nanomaterials and Sensors
  • Microfluidic and Capillary Electrophoresis Applications
  • Protein purification and stability
  • Tea Polyphenols and Effects
  • Advanced Photocatalysis Techniques
  • Quantum Dots Synthesis And Properties
  • Genetics, Aging, and Longevity in Model Organisms
  • Pesticide Residue Analysis and Safety
  • Tryptophan and brain disorders

Changchun University of Science and Technology
2024

Central South University
2008-2020

Changsha University
2014-2019

A simple and sensitive fluorescence method for monitoring the activity inhibition of protein kinase (PKA) has been developed using polycytosine oligonucleotide (dC12)-templated silver nanoclusters (Ag NCs). Adenosine-5′-triphosphate (ATP) was found to enhance Ag NCs, while hydrolysis ATP adenosine diphosphate (ADP) by PKA decreased NCs. Compared existing methods assay, does not involve phosphorylation substrate peptides, which significantly simplifies detection procedures. The exhibits high...

10.1021/ac503492k article EN Analytical Chemistry 2014-12-17

Taking advantage of the protection effect single-stranded DNA oligonucleotides, gold nanoparticles (AuNPs) remain dispersed and retain a red color with addition low concentration salt, while AuNPs would aggregate in presence double-stranded DNA. This difference has been used to design label-free colorimetric sensors for detection. NaCl is most commonly salt induce aggregation AuNPs. In this work, we aimed test if other salts can provide even better sensor performance understand effects...

10.1021/acs.analchem.0c02688 article EN Analytical Chemistry 2020-08-28

Poly-C DNA is highly efficient in etching silver nanoparticles followed by Ostwald ripening at high concentrations, increasing the toxicity of nanoparticles.

10.1039/c8mh01126e article EN Materials Horizons 2018-10-09

Dark tea, rich in nutricines including tea polyphenols and free amino acids, is a kind of post-fermented tea. The potential application against oxidative damage senescence, which drives animal health maintenance disease prevention, has attracted considerable interest. In this study, the effect dark its effects on longevity defense stress was investigated Caenorhabditis elegans ( C. ) model. Under normal conditions, extended lifespan without significant impairment propagation. It also...

10.3389/fvets.2023.1342747 article EN cc-by Frontiers in Veterinary Science 2024-01-05

In this paper, a simple strategy for the sensitive detection of hydroquinone (H2Q) using fluorescent silver nanoclusters (AgNCs) has been developed. presence H2O2 and peroxidase, fluorescence AgNCs was quenched efficiently by phenolic compounds. The mechanism inherent in quenching could be mainly ascribed to formation quinone intermediates via enzyme-catalyzed oxidation Combined with high specificity enzyme, method determine compounds linear relationship ranging from 8.0 × 10−8 3.2 10−6 mol...

10.1039/c2ra21615a article EN RSC Advances 2012-10-30

A simple and efficient method for the fabrication of highly fluorescent platinum nanoclusters (Pt NCs) has been reported in which bovine serum albumin (BSA) serves as a scaffold NaBH<sub>4</sub> reductant.

10.1039/c4ra03917c article EN RSC Advances 2014-01-01

A hybridization chain reaction (HCR)-based DNAzyme fluorescent sensor is demonstrated for <sc>l</sc>-histidine (<sc>l</sc>-His) assays.

10.1039/c9ay00526a article EN Analytical Methods 2019-01-01

Abstract Both affinity capillary electrophoresis (ACE) and fluorescence spectroscopy were used to measure the binding affinities between diclofenac sodium (DFS) bovine serum albumin (BSA) in this investigation. In ACE, DFS was injected into borate buffer containing various concentrations of BSA. Mobility ratio (M) deduce constant (K b ), which effectively eliminates effect electroosmotic flow (EOF). ACE measurements indicated two classes sites The K value for high (1.9 ± 0.2 × 105 M−1)...

10.1080/10826070802225338 article EN Journal of Liquid Chromatography &amp Related Technologies 2008-07-08

Single-stranded DNA oligonucleotides have been widely used to functionalize metal nanoparticles, and the nanoparticles are often assumed be stable. We herein communicate that can both protect etch silver nanomaterials, such as triangular plates (AgTPs). For moieties with a high affinity Ag polycytosine (poly-C) polyguanine (poly-G), they display concentration-dependent etching, length was vital. Etching less effective when is folded into more compact structures. Polythymine (poly-T) adsorbed...

10.1021/acs.jpcc.9b02653 article EN The Journal of Physical Chemistry C 2019-04-22

The Hg<sup>2+</sup> fluorescence sensor based on TdT isothermal amplification DNA templated CuNCs was successfully constructed.

10.1039/c9ay01214a article EN Analytical Methods 2019-01-01

While various DNA-functionalized nanomaterials and biosensors have been reported, most of them ignored the influence DNA on stability nanoparticles. We recently noticed that cytosine guanine rich oligonucleotides can etch silver nanoparticles (AgNPs). In this work, we communicated phosphorothioate (PS) modified (PS-DNA) could AgNPs quite independent sequence, suggesting thio modifications were playing major role etching. Compared to normal (e.g. poly-C DNA), required concentration decreased...

10.3389/fchem.2019.00198 article EN cc-by Frontiers in Chemistry 2019-04-16

Abstract Anodic stripping voltammetry (ASV) has been combined on‐line with inductively coupled plasma‐mass spectrometry (ICP‐MS) using both Bi‐coated reticulated vitreous carbon (RVC) and glassy (GC) disk electrodes. Because the same flow cell is used for RVC GC electrodes, analytical performances between these two types of electrodes can be accurately compared their utilizations in ASV‐ICP‐MS technique. Comparison includes signal enhancement, reproducibility, dynamic range, hydrodynamic...

10.1002/elan.200900485 article EN Electroanalysis 2010-06-28
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