Ravikant Sharma

ORCID: 0000-0003-4341-5428
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Research Areas
  • Pancreatic function and diabetes
  • Histone Deacetylase Inhibitors Research
  • Cancer-related Molecular Pathways
  • Attention Deficit Hyperactivity Disorder
  • Diet and metabolism studies
  • Immune Cell Function and Interaction
  • Tryptophan and brain disorders
  • Diagnosis and treatment of tuberculosis
  • Arsenic contamination and mitigation
  • CAR-T cell therapy research
  • Virus-based gene therapy research
  • Cancer Mechanisms and Therapy
  • Diabetes Treatment and Management
  • Circular RNAs in diseases
  • Neurotransmitter Receptor Influence on Behavior
  • Parkinson's Disease Mechanisms and Treatments
  • Nuclear Receptors and Signaling
  • Diet, Metabolism, and Disease
  • Dietary Effects on Health
  • Genetics, Aging, and Longevity in Model Organisms
  • Metabolism, Diabetes, and Cancer
  • Pleural and Pulmonary Diseases
  • RNA Interference and Gene Delivery
  • Autophagy in Disease and Therapy
  • Circadian rhythm and melatonin

Sawai ManSingh Medical College and Hospital
2024

Oulu University Hospital
2024

University of Oulu
2023-2024

Science for Life Laboratory
2024

Uppsala University
2024

Imperial College London
2024

Istanbul Kent University
2024

National Institute of Pharmaceutical Education and Research
2023

Obesity is a risk factor for cardiometabolic diseases. Nutrients stimulate GLP-1 release; however, has short half-life (<2 min), and only <10–15% reaches the systemic circulation. Human L-cells are localized in distal ileum colon, while most nutrients absorbed proximal intestine. We hypothesized that combinations of amino acids fatty potentiate release via different L-cell receptors. secretion was studied mouse enteroendocrine STC-1 cells. Cells were pre-incubated with buffer 1 h...

10.3390/ijms25021087 article EN International Journal of Molecular Sciences 2024-01-16

Arsenic is present in above permissible safe limits groundwater, soil, and food, various areas of the world. This increasing exposure to humankind affecting health ways. Alternation cognition one among them. Epidemiological research has reflected impact arsenic on children form diminished cognition.Considering this fact, study reviewed amyloid precursor protein, which known cause commonest cognitive disorders such as Alzheimer's disease.The reviews role generation amyloid-beta from its that...

10.2174/0118761429272806231020045840 article EN cc-by Current Molecular Pharmacology 2023-11-06

Scope Diet and exercise are significant players in obesity metabolic diseases. Time‐restricted feeding (tRF) has been shown to improve responses by regulating circadian clocks but whether it acts synergically with remains unknown. It is hypothesized that forced alone or combined tRF alleviates its complications. Methods results Male C57bl6 mice fed high‐fat a control diet for 12 weeks either ad libitum 10 h during their active period. High‐fat (HFD)‐fed divided into (treadmill 1 at m min −1...

10.1002/mnfr.202300465 article EN cc-by Molecular Nutrition & Food Research 2024-02-22

Abstract: Anxiety is a common mental illness that affects large number of people around the world, and its treatment often based on use pharmacological substances such as benzodiazepines, serotonin, 5-hydroxytyrosine (MAO) neurotransmitters. MAO neurotransmitters levels are deciding factors in biological effects. This review summarizes current understanding system role modulation anxiety-related brain circuits behavior. The MAO-A polymorphisms have been implicated susceptibility to...

10.2174/1871527322666230412105711 article EN CNS & Neurological Disorders - Drug Targets 2023-04-14

Abstract Glucagon-like peptide (GLP)-1 is a hormone released by enteroendocrine L-cells after food ingestion. express various receptors for nutrient sensing including G protein-coupled (GPRs). Intestinal epithelial cells near the lumen have lower O 2 tension than at base of crypts, which leads to hypoxia in L-cells. We hypothesized that affects nutrient-stimulated GLP-1 secretion from cell line STC-1, most commonly used model. In this study, we investigated effect (1% ) on alpha-linolenic...

10.1007/s00424-024-02996-z article EN cc-by Pflügers Archiv - European Journal of Physiology 2024-07-29

Background: Tuberculosis is the leading etiology of pleural effusion in developing countries. Administration anti-tubercular therapy (ATT) cures tuberculous and reduces incidence subsequent TB, hence it important to establish diagnosis initiate proper treatment. This study aims assess treatment outcome tubercular patients treated under NTEP. Material & Methods: A prospective was done on 72 attending with at IRD, SMS Medical College, Jaipur after applying inclusion exclusion criteria from...

10.36106/ijsr/2909740 article EN International Journal of Scientific Research 2024-08-01
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