Lihong Zhao

ORCID: 0000-0003-4343-0038
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About
Contact & Profiles
Research Areas
  • Advanced Battery Technologies Research
  • Advancements in Battery Materials
  • Enzyme Production and Characterization
  • Advanced Battery Materials and Technologies
  • Bacteriophages and microbial interactions
  • Listeria monocytogenes in Food Safety
  • Probiotics and Fermented Foods
  • Vibrio bacteria research studies
  • Aquaculture disease management and microbiota
  • Protease and Inhibitor Mechanisms
  • Low-power high-performance VLSI design
  • Microbial Metabolism and Applications
  • Electric Vehicles and Infrastructure

Ocean University of China
2022-2024

Henan Polytechnic University
2024

Fibrinolytic enzymes are important components in the treatment of thrombosis-associated disorders. A new bi-functional fibrinolytic enzyme, versiase, was identified from a marine-derived fungus Aspergillus versicolor ZLH-1. The enzyme isolated fungal culture through precipitation with ammonium sulfate at 90% saturation. Additionally, it further purified by DEAE-based ion-exchange chromatography, recovery 20.4%. presented as one band on both SDS-PAGE and fibrin-zymogram, molecular mass 37.3...

10.3390/md20060356 article EN cc-by Marine Drugs 2022-05-27

Phage therapy was taken as an alternative strategy to antibiotics in shrimp farming for the control of Vibrio species parahaemolyticus and alginolyticus, which cause substantial mortality significant economic losses. In this study, a new phage vB_ValM_PVA8 (PVA8), could efficiently infect pathogenic isolates V. alginolyticus parahaemolyticus, isolated from sewage water characterized by microbiological silico genomic analyses. The be member Straboviridae family with elongated head contractile...

10.3389/fmicb.2023.1105924 article EN cc-by Frontiers in Microbiology 2023-05-12

In this study, isolate Bacillus velezensis1-3 was selected out for its anti- Listeria potency, from which a novel circular bacteriocin, velezin, purified of the fermentate, and then characterized. Facilitated with broad antibacterial spectrum, velezin has demonstrated decent inhibitive activity against foodborne pathogen L. monocytogenes ATCC 19115. It exerted through damaging membrane integrity targeted cell causing leakage vital elements, including K+ ion. noteworthy that also inhibited...

10.1016/j.heliyon.2024.e29701 article EN cc-by-nc-nd Heliyon 2024-04-22

Vibrio alginolyticus is one of the major pathogens causing vibriosis to a variety aquatic animals as well bringing about severe food safety concerns. Nowadays, phage therapy has received increasing attention an alternative antibiotics that have being limited for use in aquaculture industries. In this work, potent bacteriophage, vB_ValM_PVA23 (PVA23), which efficiently infects pathogenic strains V. alginolyticus, was isolated from sewage water and characterized by microbiological genomic...

10.3390/v15010135 article EN cc-by Viruses 2022-12-31

Bacteriocins are a family of bacterial generated and ribosomally synthesized antimicrobial peptides active against closely related bacteria. Among them, the circular bacteriocins gaining close attention for their potentials to be used in food/feed industrial application. In this study, new bacteriocin velezin, was discovered from fermentate Bacillus velezensis1-3. Facilitated with broad antibacterial spectrum, velezin has demonstrated outstanding inhibition foodborne pathogen L....

10.2139/ssrn.4471865 preprint EN 2023-01-01
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