A5029128378- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Genomics and Phylogenetic Studies
- Bartonella species infections research
- Advanced Battery Technologies Research
- Heart Failure Treatment and Management
- Plant and Fungal Species Descriptions
- Cardiac, Anesthesia and Surgical Outcomes
- Virus-based gene therapy research
- Sleep and Wakefulness Research
- Planarian Biology and Electrostimulation
- Computational Drug Discovery Methods
- Cardiac Fibrosis and Remodeling
- Intensive Care Unit Cognitive Disorders
- CRISPR and Genetic Engineering
- Viral Infections and Vectors
- Marine Ecology and Invasive Species
- Probiotics and Fermented Foods
- Natural product bioactivities and synthesis
- Enzyme Production and Characterization
- Genital Health and Disease
- Cardiovascular Function and Risk Factors
- Advanced Battery Materials and Technologies
- Listeria monocytogenes in Food Safety
- Anesthesia and Sedative Agents
Southern Medical University
2021-2025
Sichuan Agricultural University
2025
Ministry of Agriculture and Rural Affairs
2025
Lanzhou University
2025
Aerospace Center Hospital
2025
Guangdong Academy of Medical Sciences
2023-2024
Beijing Forestry University
2024
Anhui University of Technology
2024
Qinghai University
2023-2024
Dalian Medical University
2021-2024
Abstract Background The genus Caragana encompasses multiple plant species that possess medicinal and ecological value. However, some of are quite similar in morphology, so identifying this based on their morphological characteristics is considerably complex. In our research, illumina paired-end sequencing was employed to investigate the genetic organization structure tibetica turkestanica , including previously published chloroplast genome sequence 7 plants. Results lengths C. genomes were...
Patients with non-Hodgkin lymphoma (NHL) face heightened mortality and accelerated disease progression when persistently infected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This critical situation underscores the urgent need to identify risk factors establish early intervention strategies tailored this vulnerable population. The primary aim of study was investigate associated persistent SARS-CoV-2 infection in NHL patients during COVID-19 pandemic. A retrospective cohort...
Abstract Aims There is an emerging interest in elucidating the natural history and prognosis for patients with heart failure reduced ejection fraction (HFrEF) whom left ventricular (LVEF) subsequently improves. The characteristics outcomes were compared between recovered (HFrecEF) persistent HFrEF. Methods results This a retrospective study of adults who underwent at least two echocardiograms 3 months apart 1 November 2015 31 October 2019 initial diagnosis subjects divided into HFrecEF group...
In this study, isolate Bacillus velezensis1-3 was selected out for its anti- Listeria potency, from which a novel circular bacteriocin, velezin, purified of the fermentate, and then characterized. Facilitated with broad antibacterial spectrum, velezin has demonstrated decent inhibitive activity against foodborne pathogen L. monocytogenes ATCC 19115. It exerted through damaging membrane integrity targeted cell causing leakage vital elements, including K+ ion. noteworthy that also inhibited...
Despite the success of small interfering RNAs (siRNAs) in clinical settings, their fast clearance and poor delivery efficiency to target cells still hinder therapeutic effect. Herein, a new treatment system was constructed by combining thermosensitive liposomes with macrophage membrane, tumor-targeting cyclic Arg-Gly-Asp peptide, cell-penetrating thermotherapy. The found be stable; proteins were inherited from membrane. This combined thermotherapy displayed least uptake macrophages, greatest...
Pulmonary surfactant protein A1 (SFTPA1) is a member of the C-type lectin subfamily that plays critical role in maintaining lung tissue homeostasis and innate immune response. SFTPA1 disruption can cause several acute or chronic diseases, including cancer. However, little research has been performed to associate with cell infiltration response immunotherapy The findings our study describe expression profile multiple databases was validated BALB/c mice, human tumor tissues, paired normal...
Along with the recognized therapeutic outcomes of regenerative medicine, extracellular vesicles and their exosome subsets have become an alternative option for wound healing. Periplaneta americana L. (PA), ancient traditional medicinal insect, has been around 300 million years, displays magic formidable vitality environmental adaptive ability. The linkage between intrinsic amputation regeneration feature acknowledged healing benefit PA never revealed. Herein, inspired by ability exosomes to...
To investigate the effects of miR-9 on high glucose (HG)-induced cardiac fibrosis in human fibroblasts (HCFs), and to establish mechanism underlying these effects. HCFs were transfected with inhibitor or mimic, then treated normal HG. Cell viability proliferation detected by using Counting Kit-8 (CCK-8) assay Brdu-ELISA assay. differentiation collagen accumulation qRT-PCR Western blot assays respectively. The mRNA protein expressions transforming growth factor-β receptor type II (TGFBR2)...
Abstract Background Previous models for predicting delirium after cardiac surgery remained inadequate. This study aimed to develop and validate a machine learning-based prediction model postoperative (POD) in valve patients. Methods The electronic medical information of the surgical intensive care unit (CSICU) was extracted from tertiary major referral hospital southern China over 1 year, June 2019 2020. A total 507 patients admitted CSICU were included this study. Seven classical learning...
Abstract Background Numerous species within the genus Caragana have high ecological and medicinal value. However, identification based on morphological characteristics is quite complicated in genus. To address this issue, we analyzed complete plastid genome data for Results We obtained chloroplast genomes of two species, arborescens opulens , using Illumina sequencing technology, with lengths 129,473 bp 132,815 bp, respectively. The absence inverted repeat sequences indicated that they could...
Background Chimeric antigen receptor T (CAR-T) cells engineered with lentiviral and retroviral vectors have been successfully applied to treat patients B cell malignancy. However, viral integration in has the potential risk of mutagenesis, vector production demands effort is costly. Using non-integrative episomal such as minicircle generate integration-free CAR-T an attractive option. Methods results We established a novel method within few hours using simple molecular biology techniques....
Purpose Due to the existence of information opacity, there is a common problem adverse selection in process screening alternative technology start-ups (TSs) and determining investment targets by venture capital institutions, which does not reveal true value enterprises makes market inefficient. The aim this paper design an evaluation system help institutions select qualified TSs as their objective. Design A research framework four dimensions that include conception, technical innovation,...
This study investigates the adsorption and transport of nano-ZnO in Agrostis stolonifera , focusing on its effects plant physiology, biochemistry, root exudate, microbial community.
MicroRNAs let-7c and let-7f, two members of the let-7 family, were involved in regulating osteoblast differentiation have an important role bone formation. Let-7e-5p, which also belonged to presented adipose-derived stem cells mouse embryonic cells. However, let-7e-5p was unclear. Thus, this study aimed elucidate function its mechanism. Firstly, we found that mimic promoted but not proliferation MC3T3-E1 by positively expression levels osteogenic-associated genes ( RUNX2 , OCN OPN OSX ),...
Trollius, a genus in the Ranunculaceae family, has significant medicinal and ornamental value. It is widely distributed China with 16 different species accepted. However, due to lack of enough samples information sites, molecular phylogenetic relationships Trollius have been unresolved till now. Here we sequenced, assembled annotated plastomes investigate their genomic characteristics, inverted repeat (IR) boundaries, sequence repeats, hypervariable loci. In addition, this was reconstructed...
Experimental approaches to identify drug-target interactions (DTIs) among a large number of chemical compounds and proteins are still costly time-consuming. As an assistant, computational able rapidly infer potential drug or target candidates for diverse screenings on scale. The most difficult scenario (S4) tries explore the pairwise interacting between newly designed (new drugs) candidates). Few current can be applied inference DTIs in S4 because new drugs have no known existing at all. In...