Kenneth Madden

ORCID: 0000-0003-4367-557X
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About
Contact & Profiles
Research Areas
  • Frailty in Older Adults
  • Heart Rate Variability and Autonomic Control
  • Nutrition and Health in Aging
  • Balance, Gait, and Falls Prevention
  • Physical Activity and Health
  • Health disparities and outcomes
  • Aging and Gerontology Research
  • Cerebral Palsy and Movement Disorders
  • Cardiovascular Syncope and Autonomic Disorders
  • Psychological Well-being and Life Satisfaction
  • Stroke Rehabilitation and Recovery
  • Cardiovascular Health and Disease Prevention
  • Health Systems, Economic Evaluations, Quality of Life
  • Obesity, Physical Activity, Diet
  • Attachment and Relationship Dynamics
  • Cardiovascular and exercise physiology
  • Mental Health Research Topics
  • Body Composition Measurement Techniques
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Stress Responses and Cortisol
  • Behavioral Health and Interventions
  • Diet and metabolism studies
  • Dementia and Cognitive Impairment Research
  • Chronic Disease Management Strategies
  • Blood Pressure and Hypertension Studies

University of British Columbia
2016-2025

Vancouver Coastal Health
2013-2025

Vancouver Coastal Health Research Institute
2019-2025

British Columbia Centre of Excellence for Women's Health
2015-2025

Stornoway Diamond (Canada)
2009-2024

SMART Reading
2024

Vancouver General Hospital
2013-2023

Amsterdam University Medical Centers
2022

University of British Columbia Hospital
2020-2022

University of Amsterdam
2022

<h3>Importance</h3> Whether exercise reduces subsequent falls in high-risk older adults who have already experienced a fall is unknown. <h3>Objective</h3> To assess the effect of home-based program as prevention strategy were referred to clinic after an index fall. <h3>Design, Setting, and Participants</h3> A 12-month, single-blind, randomized clinical trial conducted from April 22, 2009, June 5, 2018, among aged at least 70 years had within past 12 months recruited clinic....

10.1001/jama.2019.5795 article EN JAMA 2019-06-04

OBJECTIVE The relationship between increased arterial stiffness and cardiovascular mortality is well established in type 2 diabetes. We examined whether aerobic exercise could reduce older adults with diabetes complicated by comorbid hypertension hyperlipidemia. RESEARCH DESIGN AND METHODS A total of 36 (mean age 71.4 ± 0.7 years) diet-controlled or oral hypoglycemic–controlled diabetes, hypertension, hypercholesterolemia were recruited. Subjects randomly assigned to one two groups: an group...

10.2337/dc09-0149 article EN cc-by-nc-nd Diabetes Care 2009-06-09

Maintaining physical activity is an important goal with positive health benefits, yet many people spend most of their day sitting. Our Everyday Activity Supports You (EASY) model aims to encourage movement through daily activities and utilitarian walking. The primary objective this phase was test study feasibility (recruitment retention rates) for the EASY model.This 6-month took place in Vancouver, Canada, from May December 2013, data analyses February 2014. Participants were healthy,...

10.1186/2055-5784-1-4 article EN cc-by Pilot and Feasibility Studies 2015-01-12

Does spending money on others (prosocial spending) improve the cardiovascular health of community-dwelling older adults diagnosed with high blood pressure?In Study 1, 186 pressure participating in Midlife U.S. (MIDUS) were examined. In 2, 73 assigned to spend or themselves.In more people spent others, lower their was 2 years later. participants who for 3 consecutive weeks subsequently exhibited systolic and diastolic compared themselves. The magnitude these effects comparable interventions...

10.1037/hea0000332 article EN Health Psychology 2016-02-12

The Canadian Geriatrics Society (CGS) fosters the health and well-being of older Canadians adults worldwide. Although severe COVID-19 illness significant mortality occur across lifespan, fatality rate increases with age, especially for people over 65 years age. dichotomization patients by age has been proposed as a way to decide who will receive intensive care admission when critical unit beds or ventilators are limited. We provide perspectives evidence why alternative approaches should be...

10.5770/cgj.23.452 article EN Canadian Geriatrics Journal 2020-04-20

Abstract Pre-clinical and cell culture evidence supports the role of ketone beta-hydroxybutyrate (BHB) as an immunomodulatory molecule that may inhibit inflammatory signalling involved in several chronic diseases such type 2 diabetes (T2D), but studies humans are lacking. Therefore, we investigated anti-inflammatory effect BHB across three clinical trials. To investigate if suppressed pro-inflammatory cytokine secretion, treated LPS-stimulated leukocytes from overnight-fasted adults at risk...

10.1093/cei/uxad138 article EN Clinical & Experimental Immunology 2024-01-09

Background and aims Cardiovascular co-morbidities are prevalent after stroke, with heart disease, hypertension impaired glucose tolerance present in the majority of cases. Exercise has potential to mediate cardiovascular risk factors commonly people stroke. This single-blinded randomized controlled trial compared effects high versus low intensity exercise on fitness, factors, cardiac function Methods Fifty participants (age 50–80 y, &gt;1 y post-stroke) were a high-intensity Aerobic (AE) or...

10.1111/ijs.12156 article EN International Journal of Stroke 2013-10-22

Overall time spent in moderate-to-vigorous intensity physical activity (MVPA) and sedentary behavior are both correlated couples. Knowledge about the nature psychosocial correlates of such dyadic covariation could inform important avenues for promotion.The present study investigates hour-by-hour between partners (i.e., synchrony) MVPA as engage their daily lives links it with person-level MVPA/sedentary behavior, temporal characteristics, relationship variables.We used 7-day accelerometer...

10.1093/abm/kaz019 article EN Annals of Behavioral Medicine 2019-05-29

10.1016/j.ahr.2025.100220 article EN cc-by-nc-nd Aging and Health Research 2025-01-01

Abstract Objective Exercise is an evidence-based strategy for preventing falls. However, its efficacy may vary based on individual characteristics, like gait speed. The study examined whether baseline speed modified the effects of home-based exercise subsequent falls among older adults. Methods This a secondary analysis 12-month, randomized controlled trial in community-dwelling adults who were ≥ 70 years old and had fallen within previous 12 months. Participants to either months (n = 172)...

10.1093/ptj/pzaf008 article EN cc-by-nc-nd Physical Therapy 2025-01-29

This study examines intra- and interindividual differences in everyday goal pursuit older adults focusing on the role of emotions representations. Assuming a prioritization self-preservation old age, we expected that reduced negative (and elevated positive) would be associated with increased pursuit. These links were to moderated by representations such positive more strongly linked greater when goals represented as hopes, whereas less fears. We used up 21 surveys from 236 individuals...

10.1038/s44271-025-00213-w article EN cc-by-nc-nd Communications Psychology 2025-03-25

Abstract Background Predicting hospital length of stay (LOS) can potentially improve healthcare resource allocation. Recent studies suggest that point-of-care ultrasound (POCUS), specifically measurements muscle thickness (MT), may be valuable in assessing patient outcomes, including LOS. This study investigates the hypothesis quadriceps MT and echo intensity (EI) predict particularly Methods Quadriceps EI were measured using POCUS patients admitted to a hospital’s acute medical unit....

10.1093/ageing/afaf103 article EN cc-by-nc-nd Age and Ageing 2025-03-28

Corroborate and extend previous evidence on individual intentions self-efficacy for moderate-to-vigorous physical activity in a sample of stroke survivors. Examine associations between joint (with their romantic partner) activity. For up to 14 consecutive days, 88 survivors (Mage = 67.84, SD 10.79; 73% male; 35% with college degree; 82% White) reported the morning, minutes engaged evening wore monitors. Individual was not related activity, but were associated higher self-reported minutes....

10.1080/08870446.2025.2496226 article EN Psychology and Health 2025-04-28

Summary. The effect of different mental states on autonomic modulation the cardiovascular system was assessed in healthy, normotensive men (n=18) and women (n=12). Heart rate variability (HRV), systolic blood pressure (BPV) arterial baroreflex function were during 4 tests at rest ((10 min+5 min recovery)×4): Control (spontaneous breathing, (SB) Mental distraction (SB+word puzzle) Conscious control breathing (paced SB rate) stress (SB+computer quiz). There no significant gender differences...

10.1111/j.1475-097x.1995.tb00544.x article EN Clinical Physiology 1995-11-01

Objective: Lowered baroreflex sensitivity (BRS) predicts mortality and occurs with increasing age diabetes. We examined whether aerobic exercise could restore arterial BRS in adults at high cardiovascular risk (diabetes, geriatric group, hypercholesterolemia, hypertension). Design: Randomized, controlled, single-blind study. Setting: VITALiTY (Vancouver Initiative to Add Life Years) Research Laboratory. Participants: Thirty-nine older (mean age, 71.5 ± 0.7 years) diet-controlled or oral...

10.1097/jsm.0b013e3181ea8454 article EN Clinical Journal of Sport Medicine 2010-07-01

Individuals who live to 85 and beyond without developing major age-related diseases may achieve this, in part, by lacking disease susceptibility factors, or possessing resistance factors that enhance their ability avoid prolong lifespan. Healthy aging is a complex phenotype likely be affected both genetic environmental factors. We sequenced 24 candidate healthy genes DNA samples from 47 individuals aged eighty-five years older (the 'oldest-old'), characterize variation present this...

10.1371/journal.pone.0006641 article EN cc-by PLoS ONE 2009-08-13

There is a well-established relationship between increased arterial stiffness and cardiovascular mortality. We examined whether long-term aerobic exercise intervention (6 months) would increase compliance in older adults with hypertension complicated by Type 2 diabetes (T2DM) hyperlipidemia. A total of 52 (mean age 69.3±0.6 years, 30 males 22 females) diet/oral hypoglycemic-controlled T2DM, hypercholesterolemia were recruited. Subjects randomly assigned to one two groups: an group months...

10.1038/jhh.2012.38 article EN cc-by-nc-nd Journal of Human Hypertension 2012-09-06

Abstract: Exercise interventions are recommended in most guidelines for the treatment of type 2 diabetes. Although suggest a combination both aerobic and resistance training, exact benefits these remain unclear. either modality alone or seems to have an identical impact on glycated hemoglobin levels, training independent effects other parameters cardio-metabolic risk. This review examines current evidence glycemic control, lipid profile, body composition, vascular health, mental health...

10.2147/dmso.s32951 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2013-07-01
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