A5086964844- Inflammatory Bowel Disease
- Treatment of Major Depression
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Eosinophilic Esophagitis
- Environmental Toxicology and Ecotoxicology
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Nanoparticles: synthesis and applications
- Attention Deficit Hyperactivity Disorder
- Immunodeficiency and Autoimmune Disorders
- PI3K/AKT/mTOR signaling in cancer
- Helicobacter pylori-related gastroenterology studies
- Neurotransmitter Receptor Influence on Behavior
- Autism Spectrum Disorder Research
- Gastrointestinal disorders and treatments
- Body Contouring and Surgery
- Malaria Research and Control
- Travel-related health issues
- Trigeminal Neuralgia and Treatments
- Bipolar Disorder and Treatment
- Migraine and Headache Studies
- Psoriasis: Treatment and Pathogenesis
- Nursing Roles and Practices
- Pediatric health and respiratory diseases
North-West University
2016-2025
University of Pretoria
2020-2023
Sefako Makgatho Health Sciences University
2023
Symrise (Germany)
2022
Imperial College London
2022
University of Johannesburg
2019-2020
Nebraska Medical Center
2020
Health Sciences North
2016
LMU Klinikum
2004-2012
Ludwig-Maximilians-Universität München
2004-2009
Objective Co-morbid depression with post-traumatic stress disorder (PTSD) is often treatment resistant. In developing a preclinical model of treatment-resistant (TRD), we combined animal models and PTSD to produce an more severe as well depressive-like behaviours. Methods Male Flinders sensitive line (FSL) rats, genetic depression, were exposed re-stress [time-dependent sensitisation (TDS)] compared stress-naive controls. Seven days after TDS stress, coping behaviours hippocampal cortical...
Post-traumatic stress disorder (PTSD) displays high co-morbidity with major depression and treatment-resistant (TRD). Earlier work demonstrated exaggerated depressive-like symptoms in a gene×environment model of TRD an abrogated response to imipramine. We extended the investigation by studying behavioural monoaminergic multiple antidepressants, viz. venlafaxine ketamine with/without imipramine.Male Flinders sensitive line (FSL) rats, genetic depression, were exposed time-dependent...
Production, use and disposal of products containing nanomaterials can lead to an increased presence these particles in the environment exposure organisms found there. It is therefore becoming increasingly necessary develop methods for screening materials possible toxic effects. Behavioural analyses have proven be a dependable accurate measure ecotoxicological risk factors. The aim current study was investigate toxicological effect two types (carbon- metal-based) on zebrafish larvae....
Introduction: Cannabis has a historical role for pharmacological analgesia/anaesthesia, as well dental anxiety.Fast-forward to today's scientific literature, there are many considerations regarding the of cannabis in dentistry.We examine endocannabinoid system and its modulation from perspective.Whilst smoking been associated with poor health, tetrahydrocannabinol (THC) intoxication can result tachycardia acute hypertension, (which could cause drug-drug interaction sedation anaesthesia),...
Background and Aims: Very recently, a North American genome-wide association study identified three novel gene variants in PHOX2B, NCF4, FAM92B as well one SNP (rs224136) the intergenic region on chromosome 10q21.1 to be associated with Crohn's disease (CD) (Nat Genet 2007;39:596–604.). However, their role European patients inflammatory bowel is unknown. Therefore, we aimed replicate these CD susceptibility large cohort analyzed potential gene-gene interactions CARD15, IL23R, ATG16L1 genes.
Background: The extension of medicine prescription rights to other healthcare providers was proposed reduce pharmacotherapeutic service delivery challenges in the South African sector. scope practice physiotherapists is being reviewed possibly include promote delivery. Objectives: Our study assessed attitudes registered inclusion their practice, including enablers and challenges, drug classes they believe be most relevant. Method: A cross-sectional descriptive survey completed using an...
Major depressive disorder (MDD) is an insidious disease and affects up to 15% of the global population. Although MDD responds a wide range pharmacological treatment options, number factors, i.e. not adhering for at least 4–12 months, contribute antidepressants being highly effective. In attempt aid clinicians in improving adherence rates among patients, current paper will divulge more detail possible explanations why individuals with find it difficult adhere prescribed regimens.
Background: Patients suffering from environmentally related health disorders show a multitude of complaints uncertain origins and often with different psychopathological background. Therefore, the Basel environmental research project collected allergological-medical, psychological-psychiatric data sample 63 patients environment-related complaints. In this publication following questions were investigated: which physical symptoms do these exhibit how differ comparative samples same goal as...
No abstract available.