A5066699169- Bacterial Genetics and Biotechnology
- Marine Biology and Environmental Chemistry
- Bacteriophages and microbial interactions
- Polymer Surface Interaction Studies
- Ammonia Synthesis and Nitrogen Reduction
- Microplastics and Plastic Pollution
- Bacterial biofilms and quorum sensing
- Geological and Geophysical Studies
- Advanced Photocatalysis Techniques
- Enzyme Production and Characterization
- Metal-Organic Frameworks: Synthesis and Applications
- Geological formations and processes
- Microbial Metabolic Engineering and Bioproduction
- Enzyme Structure and Function
- Antimicrobial agents and applications
- Hydrocarbon exploration and reservoir analysis
- RNA and protein synthesis mechanisms
- Metal and Thin Film Mechanics
- Genomics and Phylogenetic Studies
- Biofuel production and bioconversion
- Advanced Adaptive Filtering Techniques
- Methane Hydrates and Related Phenomena
- Metamaterials and Metasurfaces Applications
- Marine Ecology and Invasive Species
- Gene Regulatory Network Analysis
University of Amsterdam
2019-2025
Northwestern Polytechnical University
2021-2024
Tongji University
2018-2024
University of Wisconsin–Madison
2022
University of Electronic Science and Technology of China
2016
Jiangnan University
2015
State Key Laboratory of Food Science and Technology
2015
The electrochemical synthesis of ammonia is highly dependent on the coupling reaction between nitrate and water, for which an electrocatalyst with a multifunctional interface anticipated to promote deoxygenation hydrogenation water. Herein, by engineering surface bimetallic Ni/Co-MOFs (NiCoBDC) hydrogen-substituted graphdiyne (HsGDY), hybrid nanoarray NiCoBDC@HsGDY has been achieved toward scale-up nitrate-to-ammonia conversion. On one hand, partial electron transfers from Ni2+...
Abstract Interfacial engineering of synergistic catalysts is one the keys to achieving multiple proton‐coupled electron transfer processes in nitrate‐to‐ammonia conversion. Herein, by joining ultrathin nickel‐based metal–organic framework (denoted Ni‐MOF) nanosheets with few‐layered hydrogen‐substituted graphdiyne‐supported copper single atoms and clusters HsGDY@Cu), a tandem catalyst Ni‐MOFs@HsGDY@Cu dual‐active interfaces was developed for concerted catalysis nitrate‐to‐ammonia. In such...
To infer the biological meaning from transcriptome data, it is useful to focus on genes that are regulated by same regulator, i.e., regulons. Unfortunately, current gene set enrichment analysis (GSEA) tools do not consider whether a activated or repressed regulator. This distinction crucial when analyzing regulons since regulator can work as an activator of certain and repressor other genes, yet both sets belong regulon. Therefore, simply averaging expression differences such regulon will...
Abstract Transmission electron microscopy of cell sample sections is a popular technique in microbiology. Currently, ultrathin sectioning done on resin-embedded pellets, which consumes milli- to deciliters culture and results randomly orientated cells. This problematic for rod-shaped bacteria often precludes large-scale quantification morphological phenotypes due the lack sufficient numbers longitudinally cut Here we report flat embedding method that enables observation thousands cells per...
Abstract The bactericidal activity of several antibiotics partially relies on the production reactive oxygen species (ROS), which is generally linked to enhanced respiration and requires Fenton reaction. Bacterial persister cells, an important cause recurring infections, are tolerant these because they in a dormant state. Here, we use Bacillus subtilis cells stationary phase, as model system show that pharmacological induction membrane depolarization enhances antibiotics’ also leads ROS...
Crop stand count plays an important role in modern agriculture as a reference for precision management and plant breeding. In this study, new network—IntegrateNet—was proposed to supervise the learning of density map local simultaneously thus boost model performance by balancing tradeoff between their errors. The IntegrateNet was trained validated with image set containing 124 maize images unmanned aerial vehicle. achieved excellent result 24 test root-mean-square error 2.28...
Abstract Interfacial engineering of synergistic catalysts is one the keys to achieving multiple proton‐coupled electron transfer processes in nitrate‐to‐ammonia conversion. Herein, by joining ultrathin nickel‐based metal–organic framework (denoted Ni‐MOF) nanosheets with few‐layered hydrogen‐substituted graphdiyne‐supported copper single atoms and clusters HsGDY@Cu), a tandem catalyst Ni‐MOFs@HsGDY@Cu dual‐active interfaces was developed for concerted catalysis nitrate‐to‐ammonia. In such...
Eeyarestatin 24 (ES24) is a promising new antibiotic with broad-spectrum activity. It shares structural similarity nitrofurantoin (NFT), yet appears to have distinct and novel mechanism: ES24 was found inhibit SecYEG-mediated protein transport membrane insertion in Gram-negative bacteria. However, possible additional targets not been explored. Moreover, its activity notably better against Gram-positive bacteria, for which mechanism of action had investigated. We used transcriptomic stress...
To mimic enzymes in nature, a set of hybrid nanoarrays Cu-MOFs sealed hydrogen-substituted graphdiyne has been developed order to serve as Lewis-acid-promoted catalysts. By regulating the electron-withdrawing capability ligands bridging Cu2+ sites, these provided different levels Lewis acidity toward nitrate affinity, feature crucial for nitrate-to-ammonia conversion.
Gallium-based liquid metal (GLM) has emerged as an potential marine antifouling agent endowed with extremely useful properties, such low toxicity and unique antibacterial ability. Predicated on the bio-adhesion strategy, we herein assembled tannic acid (TA) in-situ onto surface of GLM nanodroplets effectuating formation poly( TA/PEI) adhesive layer polyethyleneimine (PEI) via Schiff-base reaction and/or Michael addition to derive poly(TA/PEI)-functionalized (GLM-PEI). Subsequently,...
The bacterium Bacillus subtilis is extensively used for the commercial production of enzymes due to its efficient protein secretion capacity. However, efficiency varies greatly between enzymes, and despite many years research, optimization enzyme still largely a matter trial-and-error. Genome-wide transcriptome analysis seems useful tool identify relevant bottlenecks, yet this day, only limited number studies have been published that focus on in B. subtilis. Here, we examined effect...
Lipid A is the active center of lipopolysaccharide which also known as endotoxin. Monophosphoryl-lipid (MPLA) has less toxicity but retains potent immunoadjuvant activity; therefore, it can be developed adjuvant for improving strength and duration immune response to antigens. However, MPLA cannot chemically synthesized only obtained by hydrolyzing (LPS) purified from Gram-negative bacteria. Purifying LPS difficult time-consuming damage structure MPLA. In this study, Escherichia coli mutant...
To cope with sudden changes in their environment, bacteria can use a bet-hedging strategy by dividing the population into cells different properties. This so-called bimodal or bistable cellular differentiation is generally controlled positive feedback regulation of transcriptional activators. Due to continuous increase cell volume, it difficult for these activators reach an activation threshold concentration when are growing exponentially. one reason why primarily observed from onset...