A5030653523- Parasitic Infections and Diagnostics
- Dermatological diseases and infestations
- Insects and Parasite Interactions
- Pharmacological Effects and Toxicity Studies
- Pediatric health and respiratory diseases
- Cancer therapeutics and mechanisms
- Polyamine Metabolism and Applications
- Drug Transport and Resistance Mechanisms
- Biochemical and Molecular Research
- Enterobacteriaceae and Cronobacter Research
Instituto Nacional de Pediatria
2015-2018
Toxocara canis is a nematode that parasitizes dogs, while humans are paratenic hosts. When infected the migrating larvae damage liver, lungs and even nervous system. Larva migrans diagnosis based on immunological techniques; however, commercial immunodiagnostic kits detect anti-T. antibodies which may cross-react with other parasites, mainly nematodes extra-intestinal migration. Moreover, do not necessarily reflect an active infection; so detection quantification of circulating antigens...
The microsporidia are a large group of intracellular parasites with broad range hosts, including humans. Encephalitozoon intestinalis is the second species most frequently associated gastrointestinal disease in humans, especially immunocompromised or immunosuppressed individuals, children and elderly. prevalence reported worldwide these groups ranges from 0 to 60%. Currently, albendazole commonly used treat microsporidiosis caused by species. However, results treatment variable, relapse can...
Multidrug resistance (MDR) commonly leads to cancer treatment failure because cells often expel chemotherapeutic drugs using ATP-binding cassette (ABC) transporters, which reduce drug levels within the cells. This study investigated clinical characteristics and single nucleotide variant (SNV) in ABCB1, ABCC1, ABCC2, ABCC4, ABCG2, their association with mortality pediatric patients central nervous system tumors (CNST). Using TaqMan probes, a real-time polymerase chain reaction genotyped 15...