Jie Liu

ORCID: 0000-0003-4388-5219
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About
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Research Areas
  • Bone and Joint Diseases
  • Tendon Structure and Treatment
  • Sports injuries and prevention
  • Bone fractures and treatments
  • Hip disorders and treatments
  • Acute Ischemic Stroke Management
  • Musculoskeletal pain and rehabilitation
  • Orthopedic Surgery and Rehabilitation
  • Hip and Femur Fractures
  • Sarcoma Diagnosis and Treatment
  • PI3K/AKT/mTOR signaling in cancer
  • Knee injuries and reconstruction techniques
  • Spine and Intervertebral Disc Pathology
  • Bone health and osteoporosis research
  • Winter Sports Injuries and Performance
  • Injury Epidemiology and Prevention
  • Collagen: Extraction and Characterization
  • Pancreatic function and diabetes
  • Liver Diseases and Immunity
  • Connexins and lens biology
  • Breast Lesions and Carcinomas
  • Infrared Thermography in Medicine
  • Dental Erosion and Treatment
  • Glycogen Storage Diseases and Myoclonus
  • Peripheral Nerve Disorders

Tianjin Medical University
2010-2024

Stomatology Hospital
2024

Tianjin Medical University General Hospital
2024

Tianjin People's Hospital
2022

Beijing Emergency Medical Center
2022

Tianjin Hospital
2022

Beijing Tongren Hospital
2022

Capital Medical University
2022

Hangzhou Normal University
2021

Affiliated Hospital of Hangzhou Normal University
2021

To study changes in the dendritic morphology of retinal ganglion cells (RGCs) cats with experimental chronic glaucoma.Chronic elevation intraocular pressure (IOP) was produced by injecting endogenous ghost red blood into unilateral anterior chamber feline eyes for 1 month. The morphologic features retrograde-labeled RGCs bilateral injection horseradish peroxidase (HRP) layers A and Aa1 lateral geniculate nucleus (LGN) were examined compared between normal glaucomatous eyes. Nissl staining...

10.1167/iovs.02-0620 article EN Investigative Ophthalmology & Visual Science 2003-06-24

Muscle contraction stimulates glucose uptake acutely to increase energy supply, but suitable cellular models that faithfully reproduce this complex phenomenon are lacking. To end, we have developed a model of contracting C 2 12 myotubes overexpressing GLUT4 with an exofacial myc-epitope tag (GLUT4 myc) and explored stimulation traffic by physiologically relevant agents. Carbachol (an acetylcholine receptor agonist) induced gain in cell surface myc was mediated nicotinic receptors. also...

10.1152/ajpendo.00773.2009 article EN AJP Endocrinology and Metabolism 2010-02-17

Metastasis is the main cause of lethality prostate cancer. Class I phosphatidylinositol 3-kinases (PI3Ks), which contain 4 isoforms, α, β, δ, and γ, are known to play important roles in cell growth, migration, invasion, so on. However, respective role each PI3K isoform cancer migration invasion remains unknown. In a study that aimed elucidate we investigated change migratory invasive ability DU145 cells after treatment with isoform-specific inhibitor. Both were potently blocked by PI3Kβ...

10.1096/fj.201800183r article EN The FASEB Journal 2018-05-24

To examine the effects of Jintiange on enhancing healing osteoporotic fractures in aged rats. An fracture model femur was established using 70 SD rats (aged > 12 months), which were randomly numbered and divided into an experimental group a control group, each with equal sample size (n = 35). The received capsule ingredients via intragastric administration, while volume saline same method. X-ray examinations conducted at 4th 12th weeks to evaluate After weeks, micro-CT scanning employed...

10.1186/s13018-024-05351-1 article EN cc-by-nc-nd Journal of Orthopaedic Surgery and Research 2024-12-18

The impact of hepatic steatosis on liver stiffness measurement (LSM) in both chronic hepatitis B(CHB) and metabolic-associated fatty disease (MAFLD) remains controversial.To determine whether LSM is affected by CHB-MAFLD.Hepatic fibrosis were assessed histological noninvasively methods. area under the receiver operating characteristic curve (AUROC) was used to evaluate diagnostic performance LSM.The prevalence MAFLD CHB patients (n = 436)was 47.5% 207). For with low amounts (F0-1 F0-2),...

10.1016/j.clinre.2022.101957 article EN cc-by-nc-nd Clinics and Research in Hepatology and Gastroenterology 2022-05-21

Beijing 2022 Olympic Winter Games was the second held amid COVID-19 pandemic.To a certain extent, it has altered way sporting activities operate.There is lack of knowledge on injury risk and illness occurrence in elite winter sport athletes pandemic.This study aimed to describe incidence injuries illnesses sustained during XXIV from February 4 20, 2022. METHODS:We recorded daily number among reported by medical staff polyclinic, venues, ambulance.We calculated as or occurring competition...

10.5847/wjem.j.1920-8642.2022.106 article EN World Journal of Emergency Medicine 2022-01-01

The utilization of intracanal medicaments is an indispensable procedure in root-canal treatment. However, the conventional still need improvement regarding antimicrobial efficacy and ease clinical operation. To address above issues, OCT/PECT@OCT + ALK composite hydrogel characterized by programming sequential release dual agents has been proposed. Thanks to self-assemble ability amphiphilic copolymer poly(ε-caprolactone-co-1,4,8-trioxa [4.6]spiro-9-undecanone)-poly(ethylene...

10.1093/rb/rbae031 article EN cc-by Regenerative Biomaterials 2024-01-01

Purpose: Foam rolling (FR) is widely used for post-exercise muscle recovery; yet, the effects of FR on skeletal inflammation and microvascular perfusion following prolonged exercise are poorly understood. We aim to address gap in knowledge by using magnetic resonance imaging (MRI) T2 mapping intravoxel incoherent motion (IVIM) sequences study acute hamstrings half-marathon running recreational runners. Methods: Sixteen healthy marathon runners were recruited. After running, was performed...

10.3389/fphys.2021.723092 article EN cc-by Frontiers in Physiology 2021-10-06

The proper cage positioning and height in lateral lumbar interbody fusion (LLIF). This study evaluated their effects on clinical radiographic outcome measures patients undergoing LLIF.This single-center retrospective analyzed the characteristics perioperative data of who underwent LLIF between January 2019 December 2020. Radiographic (lumbar lordosis [LL], foraminal height, disc [DH], segmental angle [SA], cross-sectional area [CSA] thecal sac) (Oswestry Disability Index Visual Analog Scale)...

10.1186/s12891-022-05893-7 article EN cc-by BMC Musculoskeletal Disorders 2022-12-09

The lethality of prostate cancer is mainly due to metastasis. Inhibition metastasis expected be a promising approach for therapy. Phosphatidylinositol 3-kinase (PI3K)/Akt pathway reported closely involved in cell growth, migration, etc. Objective: study investigated the antimetastatic activities pan-PI3K inhibitor ZSTK474 on DU145 cells.1. In vitro effect invasion and adhesion cells was determined with Transwell migration assay wound healing assay, Tranwell respectively. 2. signal proteins...

10.2174/1568009618666180911101310 article EN Current Cancer Drug Targets 2018-09-12

Pre-implantation sterilization procedures for tendons are important measures to reduce the risk of disease transmission, however these may compromise tendon microarchitecture and biomechanical properties varying degrees. We explore effects different on micro-histology, strength biochemical human allografts in vitro study.The were harvested from cadaveric donors after serologically screened by antibody or nucleic acid testing infectious agents. All samples divided into five groups, which...

10.1111/os.13465 article EN Orthopaedic Surgery 2022-08-24

To explore the potential effect of three allogenic bone substitute configurations on viability, adhesion, and spreading osteoblasts in vitro.Freeze-dried cortical were ground fractions divided into groups with different sizes shapes, defined as fiber (0.1 mm × 0.1 3 mm), powder (0.45-0.9 granule group (3-6 mm). MC3T3-E1 cells co-cultured within to induce cell adhesion. The configuration was captured by scanning electron microscopy confocal laser microscopy, substrate roughness values...

10.1111/os.13395 article EN cc-by-nc Orthopaedic Surgery 2022-12-01

Abstract Objective: To access the efficacy and safety of proximal femoral nail anti-rotation (PFNA) InterTAN for intertrochanteric fractures.Methods: According to Cochrane systemic analysis method, randomized control trials (RCTs) retrospective comparative observational studies which were related comparison PFNA in treatment elderly with fractures retrieved. Data independently extracted from included by two reviewers analyzed using RevMan 5.3 , quality was assessed.Results: Two RCTs seven...

10.21203/rs.3.rs-21889/v1 preprint EN cc-by Research Square (Research Square) 2020-04-24

Objective To clarify the morphological, biochemical, and biomechanical effects of peracetic acid-ethanol sterilization processing to human hamstring tendon allografts for different time periods. Methods Thirty-two fresh-frozen obtained from an allograft supplier were prepared incubated in solution (PES) containing 1% v/v acid 24% ethanol. Specimens randomly classified into four groups according PES (untreated as control group, 30 min PES30 120 PES120 240 PES240group). Light microscopy with...

10.1111/os.13030 article EN Orthopaedic Surgery 2021-09-03
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