A5078613274- Traditional Chinese Medicine Analysis
- Phytoestrogen effects and research
- Metabolomics and Mass Spectrometry Studies
- Autophagy in Disease and Therapy
- Biological and pharmacological studies of plants
- MicroRNA in disease regulation
- Mitochondrial Function and Pathology
- Atherosclerosis and Cardiovascular Diseases
- Plant-based Medicinal Research
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Cardiac Fibrosis and Remodeling
- Menopause: Health Impacts and Treatments
- Cardiovascular Function and Risk Factors
- Natural product bioactivities and synthesis
- Estrogen and related hormone effects
- Cardiac Ischemia and Reperfusion
- Circular RNAs in diseases
- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Neurological Disease Mechanisms and Treatments
- Traditional Chinese Medicine Studies
- Angiogenesis and VEGF in Cancer
- Cancer-related molecular mechanisms research
- Phytochemical Studies and Bioactivities
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2017-2025
Tianjin University of Traditional Chinese Medicine
2015-2024
Tianjin Conservatory of Music
2023
Huanggang Normal University
2021-2023
Tianjin University
2019
Tianjin International Joint Academy of Biomedicine
2013-2017
Tianjin Medical University
2016
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2000
Drug-loaded injectable hydrogels have been proven to possess huge potential for applications in tissue engineering. However, increasing the drug loading capacity and regulating release system adapt microenvironment after myocardial infarction face a challenge. In this research, an ROS-sensitive hydrogel strengthened by self-nanodrugs was constructed. A hyperbranched macromer (HB-PBAE) with multiacrylate end groups synthesized through dynamic controlled Michael addition. Meanwhile, simple...
Although Danhong injection (DHI) is the most widely prescribed Chinese medicine for both stroke and coronary artery disease (CAD), its underlying common molecular mechanisms remain unclear. An integrated network pharmacology experimental verification approach was used to decipher pharmacological of DHI on CAD treatment. A compound-target-disease & function-pathway constructed analyzed, indicating that 37 ingredients derived from DH (Salvia miltiorrhiza Bge., Flos Carthami tinctorii DHI)...
The traditional Chinese medicine Danshensu (DSS) has a protective effect on cardiac ischaemia/reperfusion (I/R) injury. However, the molecular mechanisms underlying DSS action remain undefined. We investigated potential role of in autophagy and apoptosis using I/R injury models cardiomyocytes isolated rat hearts. Cultured neonatal were subjected to 6 hrs hypoxia followed by 18 reoxygenation induce cell damage. hearts used perform global ischaemia for 30 min., 60 min. reperfusion....
Doxorubicin (DOX) is one of the most effective chemotherapy agents used in treatment hematological and solid tumors, however, it causes dose-related cardiotoxicity that may lead to heart failure patients. One major reasons was increased reactive oxygen species (ROS) production. Ginsenoside Rg3 (Rg3), powerful free radical scavengers possessed cardioprotective effects. Nevertheless, has low aqueous solubility oral bioavailability, limiting its Herein, we encapsulated through spontaneous...
Shuxuening injection (SXNI), one of the pharmaceutical preparations Ginkgo biloba extract, has significant effects on both ischemic stroke and heart diseases from bench to bedside. Its major active ingredients are ginkgo flavonol glycosides (GFGs) ginkgolides (GGs). We have previously reported that SXNI as a whole protected brain heart, but their contribution therapeutic remain unclear. Therefore, we combined experimental network analysis approach further explore specific underlying...
Background and Purpose Atherosclerosis is one of the underlying causes cardiovascular disease. Formation foam cells necrotic core in plaque a hallmark atherosclerosis, which results from lipid deposition, apoptosis, inflammation macrophages. Macrophage autophagy critical anti‐atherogenic process defective aggravates atherosclerosis by enhancing cell formation, inflammation. Hence, can be strategy for treatment. Calycosin, flavonoid Radix Astragali , displays anti‐oxidant anti‐inflammatory...