A5030635153- Insect symbiosis and bacterial influences
- Insect and Arachnid Ecology and Behavior
- Insect and Pesticide Research
- Insect-Plant Interactions and Control
- Plant and animal studies
- Phytoplasmas and Hemiptera pathogens
- Cocoa and Sweet Potato Agronomy
- Hippo pathway signaling and YAP/TAZ
- Insects and Parasite Interactions
- Mosquito-borne diseases and control
- Neurobiology and Insect Physiology Research
- Trypanosoma species research and implications
- Wnt/β-catenin signaling in development and cancer
- Cellular transport and secretion
- Modular Robots and Swarm Intelligence
- CRISPR and Genetic Engineering
- CO2 Reduction Techniques and Catalysts
- Invertebrate Immune Response Mechanisms
- Insect behavior and control techniques
- Plant Parasitism and Resistance
- Cellular Mechanics and Interactions
- Microtubule and mitosis dynamics
- Hemiptera Insect Studies
National Institute of Advanced Industrial Science and Technology
2014-2025
Kyoto University
2010-2025
University of Tsukuba
2025
École Polytechnique Fédérale de Lausanne
2018
Japan Science and Technology Agency
2010
Kobe University
2005
Abstract Some symbiotic bacteria are capable of interfering with host reproduction in selfish ways. How such can manipulate host’s sex-related mechanisms is fundamental interest encompassing cell, developmental and evolutionary biology. Here, we uncover the molecular cellular underlying Spiroplasma -induced embryonic male lethality Drosophila melanogaster . Transcriptomic analysis reveals that many genes related to DNA damage apoptosis up-regulated specifically infected embryos. Detailed...
Abstract In most eukaryotes, biparentally inherited nuclear genomes and maternally cytoplasmic have different evolutionary interests. Strongly female-biased sex ratios that are repeatedly observed in various arthropods often result from the male-specific lethality (male-killing) induced by symbiotic bacteria such as Spiroplasma Wolbachia . However, despite some plausible case reports wherein viruses raised male-killers, it is not well understood how viruses, having much smaller than...
Some
Cassidine leaf beetles are associated with genome-reduced symbiotic bacteria
Male killing is a selfish reproductive manipulation caused by symbiotic bacteria, where male offspring of infected hosts are selectively killed. The underlying mechanisms and the process their evolution great interest not only in terms fundamental biology, but also potential applications. two bacterial Drosophila symbionts, Wolbachia Spiroplasma, have independently evolved male-killing ability. This raises question whether share some similarities or specific to each species. Here, we analyse...
Some symbiotic bacteria cause remarkable reproductive phenotypes like cytoplasmic incompatibility and male-killing in their host insects. Molecular cellular mechanisms underlying these symbiont-induced pathologies are of great interest but poorly understood. In this study, Drosophila melanogaster its native Spiroplasma symbiont strain MSRO were investigated as to how the host's molecular, morphogenetic pathways involved during embryogenesis. TUNEL (terminal deoxynucleotidyl transferase dUTP...
Microbial mutualists are pivotal for insect adaptation, which often entails the evolution of elaborate organs symbiosis. Addressing what mechanisms underpin development such is evolutionary interest. Here, we investigated stinkbug Plautia stali, whose posterior midgut transformed into a specialized symbiotic organ. Despite being simple tube in newborns, it developed numerous crypts four rows, inner cavity hosts specific bacterial symbiont, during 1st to 2nd nymphal instar stages....
Growth, patterning, and apoptosis are mutually interactive during development. For example, cells that select an abnormal fate in a developing field frequently removed by apoptosis. An important issue this process needs to be resolved is the mechanism used discern their correct from fate. In order examine issue, we developed animal model expresses dioxin receptor homolog Spineless (Ss) ectopically Drosophila wing. The presence of mosaic clones expressing ss results local transformation organ...
ABSTRACT Many insects are obligatorily associated with and dependent on specific microbial species as essential mutualistic partners. In the host insects, such mutualists usually maintained in specialized cells or organs, called bacteriocytes symbiotic organs. Hence, potentially exponential growth cannot be realized but must strongly constrained by spatial resource limitations within tissues. How endosymbiotic bacteria grow, divide proliferate is important for understanding interactions...
ABSTRACT Many insects are obligatorily associated with and dependent on specific microbial species as essential mutualistic partners. In the host insects, such mutualists usually maintained in specialized cells or organs, called bacteriocytes symbiotic organs. Hence, potentially exponential growth cannot be realized but must strongly constrained by spatial resource limitations within tissues. How endosymbiotic bacteria grow, divide, proliferate is important for understanding interactions...
Abstract The origin and mechanism of male-killing, an advantageous strategy employed by maternally transmitted symbionts such as Wolbachia , remain unclear. We compared genomes four strains derived from Homona magnanima a male-killing strain w Hm-t (1.5 Mb), three non-male-killing strains, Hm-a (1.1 Hm-b (1.3 Hm-c (1.4 Mb). A Hm-t-specific 76-kbp prophage region harboured two tandemly arrayed WO-mediated killing ( wmk ) gene homologs wmk-1 / wmk-2 wmk-3 wmk-4 ). Of these, or killed almost...
Maternally transmitted bacterium Wolbachia selfishly manipulates insect reproduction. A notable feature of is male killing, whereby the sons infected females are killed during embryogenesis1; however, origin and diversity Wolbachia-induced male-killing mechanisms unclear. Herein, we identified a 76 kbp prophage region specific to by comparing genomes closely related non-male-killing strains isolated from moth Homona magnanima. The encoded homolog oscar gene that induces killing in Ostrinia...
ABSTRACT A wide variety of bacterial endosymbionts in insects are associated with reproductive parasitism, whereby they interfere host systems to spread within populations. Recent successes identifying factors responsible for parasitism have highlighted the common appearance deubiquitinase domains, although their functional roles remain unknown. For example, Spiroplasma symbionts Drosophila selectively kill male progeny a male-killing toxin Spaid that encodes an OTU domain. Here I show...
ABSTRACT Microbial mutualists are pivotal for insect adaptation, which often entails the evolution of elaborate organs symbiosis. Addressing what mechanisms underpin development such is evolutionary interest. Here we investigated stinkbug Plautia stali whose posterior midgut transformed into a specialized symbiotic organ. Despite being simple tube in newborns, it developed numerous crypts four rows, inner cavity hosts specific bacterial symbiont, during 1 st to 2 nd nymphal instar....