A5080060929- Muscle activation and electromyography studies
- Neuroscience and Neural Engineering
- EEG and Brain-Computer Interfaces
- Stroke Rehabilitation and Recovery
- Neural dynamics and brain function
- Transcranial Magnetic Stimulation Studies
- Balance, Gait, and Falls Prevention
- Motor Control and Adaptation
- Tactile and Sensory Interactions
- Prosthetics and Rehabilitation Robotics
- Advanced Sensor and Energy Harvesting Materials
- Cerebral Palsy and Movement Disorders
- Botulinum Toxin and Related Neurological Disorders
- Advanced Memory and Neural Computing
- Spinal Cord Injury Research
- Photoreceptor and optogenetics research
- Functional Brain Connectivity Studies
- Conducting polymers and applications
- Vestibular and auditory disorders
- Vagus Nerve Stimulation Research
- Nerve injury and regeneration
- Robot Manipulation and Learning
- Neurological disorders and treatments
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
Scuola Superiore Sant'Anna
2016-2025
Vita-Salute San Raffaele University
2024-2025
École Polytechnique Fédérale de Lausanne
2016-2025
Piaggio Aerospace (Italy)
2015-2024
Piaggio (Italy)
2014-2024
Wyss Center for Bio and Neuroengineering
2015-2024
Fondation Bertarelli
2022-2024
Azienda Ospedaliero-Universitaria Careggi
2024
Center for Micro-BioRobotics
2015-2023
Bioengineering (Switzerland)
2023
The mechanical mismatch between soft neural tissues and stiff implants hinders the long-term performance of implantable neuroprostheses. Here, we designed fabricated with shape elasticity dura mater, protective membrane brain spinal cord. electronic which call e-dura, embeds interconnects, electrodes, chemotrodes that sustain millions stretch cycles, electrical stimulation pulses, chemical injections. These integrated modalities enable multiple neuroprosthetic applications. extracted...
A multigrasp, bidirectional hand prosthesis delivers dynamic sensory feedback, allowing a user with amputation to achieve fine grasping force control and realistic object sensing.
Regaining Limb Movement Despite many years of intensive research, there is still an urgent need for novel treatments to help patients restore motor function after spinal cord injuries. van den Brand et al. (p. 1182 ) produced left and right hemisections at different levels the rat thoracic cause complete hind limb paralysis mimicking situation in humans with injury. Systemic application pharmacological agents, combined a multisystem rehabilitation program including robotic postural...
An anthropomorphic underactuated prosthetic hand, endowed with position and force sensors controlled by means of myoelectric commands, is used to perform experiments hierarchical shared control. Three different control strategies combined a vibrotactile feedback system have been developed tested able-bodied subjects through grasping tasks in activities daily living (ADLs). The first goal find good tradeoff between capabilities low attention required the user complete tasks, without...
This paper presents two robot devices for use in the rehabilitation of upper limb movements and reports quantitative parameters obtained to characterize rate improvement, thus allowing a precise monitoring patient's recovery. A one degree freedom (DoF) wrist manipulator two-DoF elbow-shoulder were designed using an admittance control strategy; if patient could not move handle, completed motor task. Two groups chronic post-stroke patients (G1 n = 7, G2 9) enrolled three week program including...
Epidural electrical stimulation (EES) of lumbosacral segments can restore a range movements after spinal cord injury. However, the mechanisms and neural structures through which EES facilitates movement execution remain unclear. Here, we designed computational model performed in vivo experiments to investigate type fibers, neurons, circuits recruited response EES. We first developed realistic finite element computer rat identify currents generated by To evaluate impact these on sensorimotor...
Motivation is an important factor in rehabilitation and frequently used as a determinant of outcome. Several factors can influence patient motivation so improve exercise adherence. This paper presents the design two robot devices for use upper limb movements, that motivate patients during execution assigned motor tasks by enhancing gaming aspects rehabilitation. In addition, regular review obtained performance reinforce patients' minds importance exercising encourage them to continue,...
Strong motivation for developing new prosthetic hand devices is provided by the fact that low functionality and controllability—in addition to poor cosmetic appearance—are most important reasons why amputees do not regularly use their hands. This paper presents design of CyberHand, a cybernetic anthropomorphic intended provide with functional replacement. Its was bio-inspired in terms its modular architecture, physical appearance, kinematics, sensorization, actuation, multilevel control...
Restoration of touch after hand amputation is a desirable feature ideal prostheses. Here, we show that texture discrimination can be artificially provided in human subjects by implementing neuromorphic real-time mechano-neuro-transduction (MNT), which emulates to some extent the firing dynamics SA1 cutaneous afferents. The MNT process was used modulate temporal pattern electrical spikes delivered median nerve via percutaneous microstimulation four intact and implanted intrafascicular...
Bionic hand provides accurate tactile and position information leads to improved performance during sensing tasks.
Recreated missing leg sensations, connected to the prosthesis sensors, restored functional abilities and promoted its cognitive integration.
According to amputees, sensory feedback is amongst the most important features lacking from commercial prostheses. Although restoration of touch by means implantable neural interfaces has been achieved, these approaches require surgical interventions, and their long-term usability still needs be fully investigated. Here, we developed a non-invasive alternative which maintains some advantages invasive approaches, such as somatotopic restitution scheme. We used transcutaneous electrical nerve...