A5083392956- Parasites and Host Interactions
- Global Maternal and Child Health
- Parasite Biology and Host Interactions
- Child Nutrition and Water Access
- Zoonotic diseases and public health
- School Health and Nursing Education
- Global Health and Surgery
- Economics of Agriculture and Food Markets
- Aquatic Invertebrate Ecology and Behavior
- Paleopathology and ancient diseases
- Community Health and Development
National Institute for Medical Research
2017-2024
Nelson Mandela African Institution of Science and Technology
2017-2024
Different populations of hosts and parasites experience distinct seasonality in environmental factors, depending on local-scale biotic abiotic factors. This can lead to highly heterogeneous disease outcomes across host ranges. Variable characterizes urogenital schistosomiasis, a neglected tropical caused by parasitic trematodes ( Schistosoma haematobium ). Their intermediate are aquatic Bulinus snails that adapted extreme rainfall seasonality, undergoing prolonged dormancy yearly. While have...
Significance Predicting how ecological interactions among vectors or intermediate hosts of human parasites influence transmission potential to humans remains challenging. Here, we focus on schistosomiasis and demonstrate resource competition snails profoundly alters the link between infected snails, target control, schistosome cercariae, cause infections. We integrated an individual-based bioenergetics model snail dynamics with experiments in artificial waterbodies field observations...
Schistosomiasis represents a major public health problem in Tanzania despite ongoing national control efforts. This study examined whether intestinal schistosomiasis is associated with malaria and assessed the contribution of on anaemia undernutrition school children Mara region, North-western Tanzania. Stool samples were collected from each 928 randomly selected 5 schools for using Kato Katz method. Finger prick blood parasites haemoglobin concentrations Giemsa stain Haemocue methods,...
Schistosomiasis is hyper-endemic in the Lake Victoria basin; with intestinal schistosomiasis plaguing communities adjacent to lake, where intermediate host snails live. The two species of Schistosoma mansoni Mwanza region are Biomphalaria sudanica, found on banks lakes, and B. choanomphala, lake itself. There few longitudinal surveys documenting changing abundance differential transmission patterns these across seasons years. We undertook 15 field at 26 sites over four years determine...
Administering more than one treatment may increase Praziquantel cure and egg reduction rates, thereby hastening achievement of schistosomiasis transmission control. A total 431
Schistosoma haematobium infection in endemic areas varies depending on the nature and complexity of transmission networks present. Studies micro-geographical S. indicate that discrepancy prevalence between households is associated with diverse water contact behaviors restricted to particular sites harboring snail intermediate hosts. Detection variations sources complex bodies required for optimization malacological control. Longitudinal parasitological surveys were conducted investigate...
In an effort to complement the current chemotherapy based schistosomiasis control interventions in Shinyanga district, community knowledge, perceptions and water contact practices were qualitatively assessed using focus group discussions semi structured interviews involving 271 participants one S. haematobium prevalent of Ikingwamanoti village, Northwestern, Tanzania.In October, 2016 we conducted 29 parent 16 with a total 168 informants. Adult conveniently selected from three sub-villages...
Globally school-age children, adolescents and young adults bear the highest burden of schistosomiasis. When developing a specific intervention to improve community's knowledge, attitudes, practices (KAPs), existing KAPs must be taken into account. Therefore, this study was designed determine schoolchildren's on schistosomiasis in area. A cross-sectional conducted Busanga Kibuyi villages involving 513 schoolchildren. pre-tested questionnaire used collect socio-demographic data assess KAP...
Schistosomiasis is a parasitic disease which spread through skin contact with water containing Schistosoma cercariae. Drug treatment has been the main control method, but it does not prevent reinfection. The use of soap can be complementary measure to reduce transmission. Therefore, this study investigates quantitative effect different soaps on mortality mansoni
Praziquantel (PZQ)-based mass drug administration (MDA) is the main approach for controlling schistosomiasis in endemic areas. Interventions such as provision and use of clean safe water, minimizing contacts with infested disposal human waste latrines, snail control provide additional key interventions to break transmission cycle could complement perhaps sustain benefits MDA. However, all deployed need be accepted by targeted communities. A qualitative study was conducted examine factors...
Mass drug administration of praziquantel becomes a less attractive strategy for elimination schistosomiasis in low-prevalence areas due to cost implications and low treatment compliance. We aimed determine the feasibility Test-Treat-Track-Test-Treat (5T) two villages; 5T has been successfully implemented diseases such as malaria. A total 200 school children aged 6-12 years were randomly selected from schools tested Schistosoma mansoni infection using point-of-care circulating cathodic...
Abstract Background There is growing recognition that mass drug administration must be complemented with environmental interventions to interrupt schistosomiasis transmission. Accurate mapping of snails and schistosome parasite distribution critical identify foci human exposure prioritize sites for interventions. Methodology We conducted longitudinal surveys schistosomes in 467 waterbodies across 86 villages northwestern Tanzania describe spatial temporal variation snail parasites presence...
Appropriate behaviour change with regard to safe water contact practices will facilitate the elimination of schistosomiasis as a public health concern. Various approaches effecting this have been trialled in field but limited sustainable outcomes. Our case study assessed effectiveness novel theatre-based technique (BCT), combination cohort awareness raising and capacity training intervention workshops. was carried out four rural communities Mwanza region Tanzania semi-urban town Kemise,...
Abstract Different populations of hosts and parasites experience distinct seasonality in environmental factors, depending on local-scale biotic abiotic factors. This can lead to highly heterogenous disease outcomes across host ranges. Variable characterizes urogenital schistosomiasis, a neglected tropical caused by parasitic trematodes ( Schistosoma haematobium ). Their intermediate are aquatic Bulinus snails that adapted extreme rainfall seasonality, undergoing dormancy for up seven months...